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Results: 167


Elena Stanghellini
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STEM area: Mathematics

Competences: causal inference, with applications in medicine, finance and economics, development of multivariate statistical models, graphical Markov Models, statistics

Keywords: corporate social responsibility, credit scoring, models for forecasting the default event in Small and Medium Enterprises (SME), models for individual data in biomedicine and epidemiology

Region: Umbria


Position/Role

Full Professor of Statistics at the Università degli Studi di Perugia.

Professional career

Elena Stanghellini graduated in Economics at the Università degli Studi di Firenze in 1991, where she also completed in 1995 the Ph.D. in Applied Statistics. After a position as Research Fellow at the Open University in Milton Keynes (U.K.), in 1996 she awards a permanent position as Researcher in Statistics at the Università degli Studi di Perugia, where she became full professor in 2005.

In 2005 she is consultant to the Regional Institute of Economic Planning of Tuscany (I.R.P.E.T.) for a research about the analysis and forecasts of the regional tourist flows.

In 2007 she is Visiting Professor at the Center of Research in Statistical Methodology of the University of Warwick (U.K.). 

In 2007 she is consultant to the World Bank for a survey about the environmental perceptions and behaviours of the Teheran residents.

In 2008 consultant to IRPET for the analysis of competitiveness of the European Regions.

 In 2009 consultant to the Ministry of Treasure (Department UVAL) for the development of a methodology for the definition of urban and rural areas, based on socioeconomic variables.

From 2010 to 2012 she is a member of the Research Group for the Sustainable Investment Research Program (SIRP), funded by the Swedish Foundation MISTRA.

From 2011 to 2013 she participates in the research group “Identification of Graphical Markov Models with latent variables”, with annual meetings at the American Institute of Mathematics, Palo Alto.

From 2011 to 2014, she is a member of the Swedish research group SIMSAM, to study the long term effects on health of the exposure to risk factors during childhood. 

From 2013 to 2016 she is Director of the Ph.D. program in Mathematical and Statistical Methods for Economic and Social Sciences. 

From 2014 to 2019 she is appointed Deputy Rector for International Relationships. In this position, she was responsible of the relations with foreign Universities, Italian Ministries and the National University Council (CUN). Several missions abroad.

From 2015 to 2019 she is Affiliated Professor at the Umeå University (SE).  

In 2020 she is in the Advisory Board of the national Italian Bureau of Statistics (ISTAT) for the design and implementation of sample surveys to measure and monitor epidemiological parameters of COVID-19 pandemic. Currently, she is involved in two projects, in Lombardy and Tuscany, for the analysis of COVID-19 individual data.

In 2020 and 2021 she partecipates several times at the SKY TV program “The numbers of pandemic”. In 2020 she joined the Rotary E-Club “Due Mondi”, with meetings mainly online. Presently she teaches “Statistics” and “Statistical models for Credit Scoring” and “Graphical Markov Models”.

Scientific results

Her main scientific achievements concern (a) the extension of graphical models for continuous random variables to asymmetrically distributed random variables (b) the analysis of point or interval identifiability of statistical models with missing information and (c) causal inference. 

With reference to (a) she has derived the first extension of graphical models to include Extended Skew-Normal variates. With reference to point (b) she has derived condition of identifiability of graphical models for both Gaussian and discrete random variables with one dimensional confounding factor and condition for interval identification of continuous or binary response models under informative missingness of the outcome. With reference to point (c) she has derived the parametric decomposition of the total effect with binary mediators. 

All results have been derived in cooperation with researchers from Italian and foreign universities.  From the applied viewpoint, she has worked on micro econometric data to forecast the default event in SME, to study the relationship between Corporate Social Responsibility and profitability. In epidemiology, she has been involved in the evaluation of the efficacy of a treatment in a case-control study and in the estimate of the unknown numbers of individual of an elusive population via capture-recapture methods. 

 

Editorial work and publications

Since 2011, she participates in the Editorial Board of the International Journal “Statistical Papers”.

She has published numerous scientific contributions, including the following.

[2021] Raggi M., Stanghellini E., Doretti M. Path Analysis for Binary Random Variables. Sociological Methods and Research. Forthcoming.

[2019] Stanghellini E., Doretti M.. On marginal and conditional parameters in logistic regression models. Biometrika, 106(3):732-739. 

[2018] Doretti M., Geneletti S., Stanghellini E. Missing Data: A Unified Taxonomy Guided by Conditional Independence. International Statistical Review86: 189-204.

[2014] Genbäck, M., Stanghellini E., De Luna X. Uncertainty Intervals for regression parameters with non-ignorable missingness in the outcome. Statistical Papers, 56(3): 829-847.

[2014] Nicolosi M., Grassi S., Stanghellini E. Item Response Models to Measure Corporate Social Responsibility. Applied Financial Economics, 24(22):1449-1464.

[2013] Stanghellini E., Vantaggi B. On the identification of discrete concentration graph models with one hidden binary variable. Bernoulli, 19(5A): 1920-1937.

[2011]. Hutton J.L., Stanghellini E. Modelling bounded health scores with censored skew-normal distributions. Statistics in Medicine, 30: 368–376. 

[2009] Stanghellini E. Introduzione ai metodi statistici per il Credit Scoring. Springer Verlag Italia. Monografia.

[2005] Stanghellini E., Wermuth N. On the identification of path analysis models with one hidden variable. Biometrika92(2):337-350.

[2004] Stanghellini E., Van der Heijden P.G.M. A multiple-record systems estimation method that takes observed and unobserved heterogeneity into account. Biometrics, 60: 510-516. 

[2003] Capitanio A., Azzalini A., Stanghellini E. Graphical Models for skew-normal variates. Scandinavian Journal of Statistics, 30: 129-144.

[1997] Stanghellini E. Identification of a single-factor model using graphical Gaussian rules. Biometrika 84: 241-244.

Awards and prizes

1997: Ex-aequo winner of the Prize for the best PhD Thesis in Statistics (VII Cycle) by the Italian Statistical Society.

1999: Recipient of the Jemolo Fellowship at the Nuffield College of the University of Oxford. 

2010 to date: Elected Member of the International Statistical Institute.

2011: Winner of the Square Grant by the American Institute of Mathematics.

 

Giuseppina Marilia Tantillo
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STEM area: Clinical sciences and nutrition science

Competences: food safety, veterinary medicine

Keywords: apiculture, biomolecular analysis, chemical risk, commercial frauds, coronavirus, Covid-19, Covid-19: impact on the food packaging, Covid-19: persistence of the virus on the industries, food technology, nutritional quality, sanitary controls

Region: Apulia


Position/Role

Full Professor at the Department of Interdisciplinary of Medicine (DIM) of University of Bari within the Scientific-Disciplinary Sector VET/04 “Food Safety”. Disciplines Taught including “Food Laboratory and Food Industry practices”, “Chemical analysis of foods and food products”, “Technology and hygiene of milk, meat, fish, eggs and honey”, “Food microbiology”.

Lecturer in various research PhD courses. Formerly lecturer in various Italian Public Institutes specialized in “Public  Health Services”, “Food Science”, “Meat Hygiene and Technology”

Formerly Lecturer in Food Processing Training Programmes (courses held in local Health Agencies, Desease Prevention Institutes and Food Industries)

Professional career

From 2004  to 2014 Director of Specialisation School in “Hygiene and Technology of milk and dairy products” at the University of Bari and from 2014 to 2017 Director of the Specialisation School “Food inspection” at the University of Bari.

From 2002 to 2010 Coordinator of the Doctoral School “Produzione, qualità e sicurezza degli alimenti di origine animale”.

From 2002 to 2005 President of the 1st degree course in “Scienze zootecniche e Sanità degli alimenti”.

From 2005 to 2008 President of the 2nd degree course in “Igiene e Qualità degli alimenti”.

 

Scientific results

Professor Tantillo leads many specialistic academic courses on:

-      microbiological, biomolecular and chemical characterization of food products;

-      Good Practices and HACCP procedures in food chain production.

Professor Tantillo is expert in food safety control by DNA-based, microbiological and chemical methods.

The research fields include: detection of xenobiotic compounds (mycotoxins, dioxins, PCBs, PAHs, Marine Biotoxins) in foodstuff by advanced chemical techniques; development of analytical techniques for the analysis of mycotoxins in food and feed; food microbiology; quality of honey and beehive products; hygienic-sanitary quality of traditional products.

Professor Tantillo is Scientific Coordinator of several national and international Research Projects, aimed to guarantee food safety, to assess the nutritional and functional quality of food, to develop technological innovations for food preservation, and to detect food frauds using molecular-based technologies.

 

Editorial work and publications

[2018 ] Terio, Valentina, Bottaro, Marilisa, Di Pinto, Angela, Fusco, Giovanna, Barresi, Teodosio, Tantillo, Giuseppina, Martella, Vito (2018). Occurrence of Aichi virus in retail shellfish in Italy. FOOD MICROBIOLOGY, vol. 74, p. 120-124, ISSN: 0740-0020, doi: 10.1016/j.fm.2018.02.013

 

-          [2017 ] Terio V, Bottaro M, Pavoni E, Losio M N, Serraino A, Giacometti F, Martella V, Mottola A, Di Pinto A, Tantillo G. Occurrence of hepatitis A and E and norovirus GI and GII in ready-to-eat vegetables in Italy. International Journal of Food Microbiology, 249:61-65, ISSN: 0168-1605, doi: 10.1016/j.ijfoodmicro. 2017.03.008.

-           

-          2017] Di Pinto A, Terio V, Marchetti P, Bottaro M, Mottola A, Bozzo G, Bonerba E, Ceci E, Tantillo G. DNA-based approach for species identification of goat-milk products,Food Chemistry, 229:93-97, ISSN: 0308-8146, doi: 10.1016/j.foodchem. 2017.02.067.

 

[2016] Mottola A, Bonerba E, Bozzo G, Marchetti P, Celano G V, Colao V, Terio V, Tantillo G, Figueras M J, Di Pinto A. Occurrence of emerging food-borne pathogenic Arcobacter spp. isolated from pre-cut (ready-to-eat) vegetables. International Journal of Food Microbiology, 236:33-37, ISSN: 0168-1605, doi: 10.1016/j.ijfoodmicro. 2016.07.012

 

[2015] Di Pinto A, Bottaro M, Bonerba E, Bozzo G, Ceci E., Marchetti P, Mottola A, Tantillo G. Occurrence of mislabeling in meat products using DNA-based assay, Journal of Food Science and Tecnology, 52:2479-2484, ISSN: 0022-1155, doi: 10.1007/s13197-014-1552-Y.

 

 

 

Stefania Tarquini
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STEM area: Engineering

Competences: aerospace engineering, spacecraft operations

Keywords: ESA (European Space Agency), space, Spacecraft

Region: ABROAD


Position/Role

LEO Spacecraft Operations Engineer in EUMETSAT, the European Meteorological Satellite Organization

Professional career

Stefania Tarquini graduated from Politecnico di Milano in Aerospace Engineering in 2010 and in 2012 she obtained a Master of Science is Space Engineering, including a study experience abroad to develop her Master thesis in the United States at the Pennsylvania State University.

During her studies, she worked in her free time for an extra-curricular project, the European Student Moon Orbiter (ESMO). The spacecraft ESMO was a project of the European Space Agency, managed in cooperation with the English company Surrey Satellite Technology Ltd (SSTL), the first lunar spacecraft to be designed, built and operated by students across ESA Member States and ESA Cooperating States. Stefania Tarquini worked for one year as a technical engineer for the propulsion subsystem, before becoming in charge of the whole team of Politecnico di Milano, leading more than 10 students with engineering tasks for the propulsion sub-system and coordinating the activities with the industry.

Only four months after graduation, Stefania Tarquini is hired by Telespazio Vega Deutschland (Finmeccanica group) as Spacecraft Controller in Darmstadt, Germany, where she was executing routine and contingency operations for the GEO satellites Meteosat 7, 8, 9 and 10 and their relative ground stations.

During the two years as Spacecraft Controller, Stefania Tarquini was noticed for her technical and managerial skils and in 2015 she was hired directly by EUMETSAT as Spacecraft Operations Engineer for the Metop series of satellites, part of the EUMETSAT Polar System (EPS) program, which provides direct observations about ocean, land and atmospheric parameters to be used for weather forecast and climate monitoring.

In 2018 she had a leading role for the launch of Metop-C, the last satellite of the series. Stefania Tarquini was acting as Customer Representive and interface between EUMETSAT and the European Space Agency, which was in charge of the Launch and Early Operation Phase (LEOP) activities. She was also coordinating the activities of the team for the Spacecraft In-Orbit Verification (SIOV) phase, when all the satellite instruments are switched on, tested and operated for the first time.

After the Metop-C launch in November 2018, Stefania Tarquini now follows the routine operations of the Metop series of satellites as platform expert and she leads an End-Of-Life Technological Test project on the Metop-A satellite, which includes as well finding stable solutions to de-orbit the satellite in a “clean” way with no space debris.

In the following years Stefania Tarquini will participate as well to the operations preparation of the EPS-SG constellation, the second generation of more modern Metop satellites to be launched in 2023.

Scientific results

During the research experience in the United States to develop her Master thesis, Stefania Tarquini worked for the selection of a new superhydrophobic material with anti-icing properites to be used on helicopter rotor blades. The work included design of aerodynamic profiles and testing of the specimens on real rotor blades in an icing chamber at the “Penn State Vertical Lift Research Center of Excellence”, developing afterwards several publications on the topic.

Throuought the ESMO project she acquired an extensive knowledge of satellite propulsion subsystems, focusing especially on liquid propellants but not forgetting as well solid and hybrid combustion materials, the latter the main focus of the research for her Bachelor thesis about new materials for innovative hybrid propellants.

Nowadays ’s main area of expertise is in the field of Spacecraft Operations for a Low Earth Orbit satellite, with three-axis stabilization and with focus on Earth Observation. She specializes in satellite platforms, with focus on attitude and orbit control, power and thermal subsystems.

As Spacecraft Operations engineer, her strengths are also about quick problem solving and spacecraft anomaly handling: the Metop satellites have short windows of commandability and the team has to be able to react quickly in case of need.

As Metop Platfrom Team Leader for EUMETSAT, She is also in charge of coordination with the Industry Spacecraft Provider Airbus and aftr additional studies to obtain the PRINCE2 certification in Project Management, she is now the Project Manager for Metop-A End of Life. 

Editorial work and publications

[2018] S. Tarquini,”Planning an End-Of-Life Technology Test Campaign for the Metop-A satellite”, Proceeding of SpaceOps Conference 2018, Marseille.

[2014] S. Tarquini, C. Antonini, A. Amirfazli, M. Marengo & J. Palacios, “Investigation of Ice Shedding Properties of Superhydrophobic Coatings on Helicopter Blades”, Cold Regions Science&Technology, 100, 50–58.

[2013] S. Tarquini, Carlo Antonini, A. Amirfazli, J. Palacios, M. Marengo, “Assessing Icephobicity Of Superhydrophobic Surfaces As Passive Coating Icing Mitigation Strategy On Helicopter Blades”, Proceeding of ILASS 2013, Chania, Crete, 1-4 September 2013. 

[2012] S. Tarquini, L. Ferrario, A. Devereaux, L. Rossettini, “Design and Development of a Dual Mode Bipropellant Propulsion System for the European Student Moon Orbiter”, Proceeding of 3AF-ESA-CNES Space Propulsion 2012, Bordeaux, 7-10 May 2012.

Awards and prizes

Prize "PoMiLIA-61" for the most outstanding dissertation of 2012 in the topic of innovative solutions to save energy in the aerospace sector (Jul 2013).

Ines Testoni
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STEM area: Psychology and neurosciences

Competences: dignity therapy, end-of-life education, Photo-Therapy

Keywords: coronavirus, Covid-19, critical incidents in prison, death, living will, media communication, moral distress among physicians, mourning, palliative care, resilience and spirituality, social denial of death, suicide

Region: Veneto


Position/Role

Associate professor of Social Psychology and Director of the Master in Death Studies & The End of Life at University of Padua

Professional career

After graduating in Applied Psychology at University of Padua in 1989, she continued her studies for a Specialization in "Clinic and Theory of Systemic Therapy" at the "Gregory Bateson Center", Niguarda Ca' Granda Hospital in Milan. In 1995 she graduated in Theoretical Philosophy with Professor Emanuele Severino at Ca' Foscari University, in Venice. In 1996 she obtained the specialization in "Cultural and Social Anthropology" at the University of Padua. In 1991 she was appointed as assistant under command from the Ministry of Education to the chair of Social Psychology at University of Padua, where she became a researcher in 1999 and associate professor in 2003. In 2017 she obtained the national qualification as full professor.

During her activity she leaded countless national and international projects, among which two European ones. She was Visiting Professor at the Universidade De Caxias do Sul (UCS), at the Semmelweiss University of Budapest (Hungary).

At University of Padova, she has been teaching at the Doctoral School in "Social Sciences. Interactions, Communication, Cultural Constructions"; teaches "Psychology of group and system relations" and "Fundamentals of Social Psychology" at the SPGI Department, and "Psychology of end-of-life relationships, bereavement, loss and death" at the FISPPA department, where she created and has been leading the Master in “Death Studies and the End of Life”, continually since 2008. Since 2018 she has been a research fellow at the Emili Sagol Creative Arts Therapies Research Center, University of Haifa (Israel).

Scientific results

She is affiliated to numerous research organizations among which: the Italian Society of Palliative Care (SICP) and of the parallel European Association of Palliative Care (EACP), she is part of the Steering Group of the Bereavement Network in Europe (BNE); International Society for Research on Aggression (ISRA); Federation of European Psychodrama Training Organizations (FEPTO). Furthermore, she is a member of the National Conference of Masters in Palliative Care and Pain Therapy, established by the Ministry of University and Research (MIUR), and has been scientific director of about ten international conferences on the topics of death, dying and palliation.

Her research is centred on Severin's concept of "nihilism", in particular on the representations of death as annihilation, on which her fundamental themes are pivoted among which: psycho-thanatology, Death Education, grief processing and treatment, human death attitudes/behavior and pathological suffering (suicide, drug addiction, anorexia and suicide, gender-based violence); loss, grief and mourning; social construction of bio-political and bio-ethical management of death; Dignity Therapy; Informed consent; Mind-brain conceptualization and social representation of death; Self-determination and biological will; Death/spirituality/religiousness; Coping with death and dying; Terror Management Theory; Counselling and therapy;  Professional training; Psychodrama and photo-voice/photo-therapy for mourners; Death and "sociatry" in social violence (gender based violence and discrimination; mafia dynamics).

Editorial work and publications

Ines Testoni is the author of about ten volumes and curator of about as many texts, about a hundred articles and contributions to collective works of national and international importance, including:

Testoni, I., Piscitello, M., Ronconi, L., Zsák, É., Iacona, E., Zamperini, A. (2019) Death Education and the Management of Fear of Death Via Photo-Voice: An Experience Among Undergraduate Students, Journal of Loss and Trauma, doi: 10.1080/15325024.2018.1507469

Testoni, I., Ronconi, L. Noppe Cupit, I., et al. (2019) The effect of death education on fear of death amongst Italian adolescents: A nonrandomized controlled study, Death Studies, doi: 10.1080/07481187.2018.1528056

Testoni I., Mariani C., Zamperini A. (2018). Domestic Violence Between Childhood Incest and Re-victimization: A Study Among Anti-violence Centers in Italy, Frontiers in Psychology,  doi: 10.3389/fpsyg.2018.02377

Testoni, I., Ronconi, L., Palazzo, L., Galgani, M., Stizzi, A., Kirk, K.(2018). Psychodrama and moviemaking in a death education course to work through a case of suicide among high school students in Italy. Frontiers in Psychology, doi:10.3389/fpsyg.2018.00441

Testoni, I., De Cataldo, L., Ronconi, L., & Zamperini, A. (2017). Pet loss and representations of death, attachment, depression, and euthanasia. Anthrozoös, doi:10.1080/08927936.2017.1270599

Luisa Torsi
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STEM area: Chemistry

Competences: analytical chemistry, bioelectronics, diagnostics, materials science and technology

Keywords: analytical chemistry, bioelectronics, biosensors, coronavirus, Covid-19, environment, hiv, inventions, materials science, nanotechnologies, odor machine, sensors, virus detection, women and science

Region: Apulia


Position/Role

Full professor of Chemistry at the University of Bari (Italy) and adjunct professor at the Abo Academy University in Finland.

Professional career

She holds a degree in Physics and a PhD in Chemistry from UNIBA and was a post-doctoral fellow at Bell Labs in the USA. In 2010 Torsi was awarded the H.E. Merck Prize by the well-known multinational company, and to date she is still the only woman to have received this prestigious international award. In 2019, she was awarded the Distinguished Women Award by the International Union of Pure and Applied Chemistry - IUPAC. She was also the only woman president of the European Material Research Society which, with more than 4000 members, is the largest of its kind in Europe. Torsi is the author of more than 200 papers, some of which have been published in high impact journals such as Science and Nature. Her work has garnered almost 13,000 citations, contributing to an h-index of 54 (google scholar). Research funding of more than €26 million includes several national and European projects, of which Torsi is often the coordinator. Luisa Torsi is also highly engaged as a role model for young female scientists. In a recent Bracco Foundation campaign, she starred in a TOPOLINO story as Louise Torduck, a successful scientist from the Calisota Valley.

Scientific results

Luisa Torsi's research focuses on bio-electronic transistor systems capable of detecting a single protein marker or a single virus in a real, non-pretreated sample of blood or saliva (10 zeptomolar concentration). The interface of the device, which responds in a few minutes and can be manufactured at low cost, is orders of magnitude larger than the single protein to be detected. This is a world record based on the Single-Molecule with a large Transistor -SiMoT technology patented by Torsi and his group in 2018. The prospect is the development of ultra-sensitive, fast, low-cost and high-reliability diagnostics for ultra-early screening of progressive diseases such as cancers and both viral and bacterial infections.

Editorial work and publications

Torsi has authored almost 200 ISI papers, including papers published in Science, Nature Materi-als, Nature Communications, PNAS and is co-inventor of several awarded international patents. Her works gathered almost 11.000 Google scholar citations resulting in an h-index of 50 (ISI h-index: 43).

(2020) Macchia E., Picca R.A., Manoli, K., Di Franco, C., Blasi, B., Sarcina, L., Ditaranto, N., Cioffi, N., Österbacka, R., Scamarcio, G., Torricelli, F., Torsi L.* About the amplification factors in organic bioelectronic sensors. Materials Horizons, 7, 999 – 1013. 2020 Materials Horizons most popular article.

(2019) Macchia, E., Tiwari, A., Manoli, K., Holzer, B., Ditaranto, N., Picca, R.A., Cioffi, N., Di Franco, C., Scamarcio, G., Palazzo, G., Torsi, L.*Label-free and selective single-molecule bioelectronic sensing with a millimeter-wide self-assembled monolayer of anti-immunoglobulins. Chemistry of Materials, 31, 6476-6483.

(2018) Macchia, E., Manoli, K., Holzer, B., Di Franco, C., Ghittorelli, M., Torricelli, F., Alberga, D., Mangiatordi, G.F., Palazzo, G., Scamarcio, G., Torsi, L.* Single mo-lecule detection with a millimetre-sized transistor. Nature Communications, 9, 3223; Highlighted in Nature: https://www.nature.com/articles/d41586-018-05950-z

(2017) Holzer., B., Manoli, K., Ditaranto, N., Macchia, E., Tiwari, A., Di Franco, C., Scamarcio, G., Palazzo, G., Torsi, L. Characterization of Covalently Bound Anti-human Immunoglobulins on Self-assembled Monolayer Modified Gold Elec-trodes. Advanced Biosystem, 1, 1700055.

(2016) Macchia E, Alberga D, Manoli K, Torsi L, et al. Organic bioelectronics probing conformational changes in surface confined proteins. Scientific Reports, 6, 28085

(2015) Macchia E, Giordano F, Magliulo M, Torsi L, et al. An analytical model for bio-electronic organic field-effect transistor sensors.Applied Physics Letters, 106(2). 

(2015) Afzal A, Di Franco C, Mesto E, Torsi L, et al. Au/In2O3 and Au/ZrO2 composite nanoparticles via in situ sacrificial gold electrolysis.  Materials Express, 5(3):171-179

(2015) Mulla M Y, Tuccori E, Magliulo M, Torsi L, et al. Capacitance-modulated transistor detects odorant binding protein chiral interactions, Nature Communications, 6,6010

(2015) Palazzo G, De Tullio D, Magliulo M, Torsi L, et al. Detection Beyond Debye's Length with an Electrolyte-Gated Organic Field-Effect Transistor. Advanced Materials, 27(5):911-916. 

(2013) Torsi L et al. Organic field-effect transistor sensors: a tutorial review. Chemical Society Reviews, 42(22):8612-8628. 

(2008) Torsi L, et al. A sensitivity-enhanced field-effect chiral sensor. Nature Materials, 7(5): 412-417. 

(1995) Dodabalapur A, Katz EH, Torsi L, et al. Organic Heterostructure Filed-Effect Transistors.Science, 269 (5230):1560-1562. 

(1995) Dodabalapur A, Torsi L, Katz EH. Organic Transistors - 2 dimensional transport and improved electrical characteristics. Science, 268 (5208):270-271.

Awards and prizes

In 2010, she was the first Italian and the first woman to win the Henrick Emmanuel Merck Prize for Analytical Sciences, an international award given to scientists who have invented a method of analysis capable of improving the quality of life of citizens. She received it for the invention of the bio-electronic sensor that can be printed on plastic or paper.

In 2013 she was awarded the itwiin prize as "Best Italian inventor of 2013" by the Italian Association of Women Inventors and Innovators.

In 2015 Euwiin International 2015 (European Union WomenInventors&Innovators Awards) awarded her the title of Best European Inventor in the "Inventor" section (first place overall).

In 2015 she was the President of the European Material Research Society, the first woman to hold this position.

In 2021, it was awarded the Wilhelm Exner Medal, a prestigious award conferred since 1921 in the presence of the Austrian President by the Austrian Association of Small and Medium-sized Enterprises to celebrate excellence in research and science.

 

 

Daniela Trabattoni
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STEM area: Biomedical sciences and biotechnology

Competences: clinical cardiology, invasive cardiology

Keywords: coronavirus, Covid-19, Covid-19: acute coronary syndromes, Covid-19: gender medicine, gender-specific medicine, preventive medicine

Region: Lombardy


Position/Role

Chief, Invasive Cardiology Unit;

Director,  Women Heart Center

Centro Cardiologico Monzino, IRCCS- Milan

 

Professional career

Graduation in Medicine at the University of Milan in 1992; board in Cardiology at the University of Milan in 1997.

Visiting fellow in the Intravascular Ultrasound Laboratory, Catheterization Lab, Washington Hospital Center (1997-1998).

In 1998 she becomes staff member of the Cath Lab at the Centro Cardiologico Monzino and Assistant Director in 2014. She is elected Chief of the Invasive Cardiology Unit at the same Institute in October 2017 and Director of the Women Heart Center, she founded in 2017, focused on cardiovascular prevention in women. 

Teaching clinical cardiology at the postgraduate cardiology school, University of Milan.

She is elected committee member of the National Superior Institute of Health (ISS) for cardiovascular devices evaluation in 2011 and member of the ISS committee for a ministerial consensus document on gender-based medicine.

 

Scientific results

Daniela Trabattoni focuses her research interests in interventional cardiology section, evaluating factors possibly affecting PCI outcomes, according to different coronary devices use. She has studied cardioprotective tools adopted during primary angioplasty as adjunctive therapy for a faster left ventricle function recovery, after acute myocardial infarction.

She has studied potential correlations between patent foramen ovale and migraine and compared different occluder devices in PFO closure.

She actively contributed to the writing of the national consensus document on antiplatelet treatment management in patients with previous coronary stenting addressed to any surgery, by the GISE (Italian Society of Invasive Cardiology).

She has studied safety and efficacy of short-term antiplatelet therapy after drug-eluting and drug-coated stents in high-bleeding risk patients.

 

Actively working at international collaborative research projects:

 

1.      Acute and 30-day outcomes in women after TAVR: Results from the WIN-TAVI (Women’s International Transcatheter Aortic Valve Implantation) Real World Registry. JACC Cardiovasc Interv.2016

 

2.     Perioperative management of antiplatelet therapy in patients with coronary stents undergoing cardiac and non-cardiac surgery: a consensus document from Italian cardiological, surgical and anesthesiological societies.  Eurointervention, 2014;

 

3.      Acute procedural and six-month clinical outcome in patients treated with a dedicated bifurcation stent for left main stem disease: the TRYTON LM multicentre registry. EuroIntervention, 2013

 

Editorial work and publications

She is reviewer of national and international cardiology journals (G Ital di Cardiologia, J Cardiovasc Medicine, International J Cardiology, Cathet Cardiovasc Interv, Cephalalgia, Circulation Cardiovasc Interventions)

 

Editorial Board member: J Endovasc Therapy (2010-2013); Journal of Hypertension and Immunotherapy (2017); BMC Cardiovascular Disorders (2017)

 

 

She authored and co-authored 518 papers (114 peer-review manuscripts, 400 abstracts, 4 chapters book) on national and international journals.

 

                                              

                                                                                             

1)    D. Trabattoni, AL. Bartorelli, F. Fabbiocchi, P. Montorsi, P. Ravagnani, M. Pepi, F. Celeste, A. Maltagliati, G. Marenzi, W.O’Neill. Hyperoxemic perfusion of left anterior descending coronary artery after primary angioplasty in anterior ST-elevation myocardial infarction. Cathet and Cardiovasc Interv, 2006; 67:859-865.DOI:10.1002/ccd.20704

 

                                                                                                                                             

2)    D. Trabattoni, F. Fabbiocchi, P. Montorsi, S. Galli, G. Teruzzi, L. Grancini, P. Gatto, A.L. Bartorelli. Sustained long-term benefit of PFO closure on migraine. Cath Cardiovasc Interv, 2011; 77 (4):570-574.doi: 10.1002/ccd.22826                                                                                                          

                                                                                              

3)    D. Trabattoni,A. Bartorelli.IVUS in bifurcation stenting: what have we learned? Eurointervention suppl 2010; 6: J88-J93. doi: 10.4244/EIJV6SUPJA14                                 

4)    D. Trabattoni,F. Fabbiocchi,S. Galli, P. Montorsi, A. Lualdi, L. Grancini, Ravagnani, A.L. Bartorelli. Sex difference in long-term clinical outcome after sirolimus-eluting stent implantation. Coron Artery Dis, 2011; 22(6):442-6. DOI 10.1097/MCA.0b013e3283475056                                                             

 

5)    Trabattoni D, Gaspardone A, Sgueglia GA, Fabbiocchi F, Gioffrè G, Montorsi P, Calligaris G, Iamele M, De Santis A, Bartorelli AL. AMPLATZER versus Figulla occluder for transcatheter patent foramen ovale closure. EuroIntervention. 2017;12(17):2092-2099. doi: 10.4244/EIJ-D-15-00499.

 

6)    Trabattoni D, Fabbiocchi F, Montorsi P, Galli S, Ravagnani P, Calligaris G, Teruzzi G, Grancini L, Troiano S, Ferrari C, Bartorelli AL. A Long-term Single-center Registry of 6,893 Patients Undergoing Elective Percutaneous Coronary Intervention With the Xience Everolimus-Eluting Stent.J Invasive Cardiology, 2019; in press

 

 

Awards and prizes

Fellow of the Italian Society of Cardiology  (1995-present).

Fellow of the European Society of Cardiology (2001-present)

Member of the Italian Group of Invasive Cardiology  (2001-present)

Fellow of the American College of Cardiology (2005-present)

Member of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) (2007-present)

Rosa Camuna award – by Regione Lombardia (2009)

 

 

Clara Troncon
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STEM area: Physics

Competences: nuclear physics, particle physics

Keywords: CERN, geneva, higgs boson, nuclear physics, standard model

Region: Lombardy


Position/Role

Senior researcher at the Istituto Nazionale di Fisica Nucleare (INFN), Milano section.

 

Professional career

Graduated in Physics at the University of  Trieste in 1977. In 1978 Summer Student at CERN, Geneva (CH) and then PHD student in Trieste. In 1979 I have been awarded an Amelia Earhart Fellowship from the Zonta International Foundation. The Amelia Earhart Fellowship was established in 1938 as a way to support women interested in aerospace-related sciences and engineering and is awarded annually through an international competition to 30 women pursuing Ph.D./doctoral degrees in this area.

In 1980 I have been awarded a Research Grant from the Fondazione “Angelo Della Riccia”. The grants are intended to subsidize research periods abroad for Italian young postdoctoral researchers or advanced graduate students in Physics. The recipients are selected annually,  through a competition at a National level.  The “Angelo Della Riccia” grant contributed funding my first postdoctoral position at CERN.

I became staff researcher in INFN (Istituto Nazionale di Fisica Nucleare) in Trieste in 1983 and then moved to Milano.

I am scientific associate at CERN since 1978.

Scientific results

I have participated to an important discovery and to prominent measurements in the field of Elementary Particle Physics with accelerators,  i.e.  studies of properties of Heavy Flavours,   precision measurements of Standard Model, including the search and then discovery of Higgs boson and search for new physics beyond the Standard Model. My research activity starts at CERN, where in 1979-1986 I studied charm physics within the experiments of European Hybrid Spectrometer (EHS) at the Super Proton Syncrotron (SPS) accelerator. In 1986-2000, I participated to DELPHI experiment at the Large Electron Positron (LEP) accelerator, where I contributed to precision measurements of Z0 and W bosons, to tests of Standard Model and search for Higgs boson, as well as to the construction, operation and upgrade of its silicon vertex detector. In 1997 I joined the project to construct the ATLAS experiment at the Large Hadron Collider (LHC) at CERN, playing an important role in the construction of the pixel detector. After the installation of this detector, (2008-present), I dedicated to the search, discovery  and study of Higgs boson and to the search of SUSY particles and BSM physics.

Regarding Instrumentation I work (1986-present) in the development of silicon detectors, both microstrip and pixel detectors, as well as in the construction, commissioning and operation of vertex detectors.

 

Editorial work and publications

Member of the INFN Evaluation Panel working group (2012-present)

Italian delegate in the CERN Advisory Committee of CERN Users (2013-present)

ACCU representative in the CERN Scientific Information Policy (2015-present)

Member of GEV02 (Gruppo Esperti della Valutazione per le Scienze Fisiche) (2015-2017) for the VQR 2011-2014 (Valutazione della qualita’ della Ricerca)  (ANVUR-MIUR) and coordinator of subGEV02 (Fisica sperimentale, Particelle e Nucleare)

Elected member of the INFN CSN1 (Commissione Scientifica Nazionale 1 –   Particle physics with accelerators) (2006-2012)

Referee of Babar experiment (INFN) (2006-2012) in CSN1

Awards and prizes

more than 1100 publication.

-         h-index in Google Scholar: 164

-         H-index ISI/Web of Science: 88

-         H-index SCOPUS : 86

Most prominent publications:

(2013) ATLAS Collaboration, Aad G, Troncon C, et al. Evidence for the spin-0 nature of the Higgs boson using ATLAS data. Physical Review Letters B, 726, 120-144.

(2012) ATLAS Collaboration, Aad G, Troncon C, et al. Observation of a new particle in the search for the Standard Model Higgs boson with the ATLAS detector at the LHC. Physical Review Letters B, 716, 1-29.

(2010) ATLAS Collaboration, Aad G, Troncon C, et al. Observation of a Centrality-Dependent Dijet Asymmetry in Lead-Lead Collisions at √sNN=2.77 TeV with the ATLAS Detector at the LHC. Physical Review Letters, 105, 252303.
(2008) ATLAS Collaboration, Aad G, Troncon C, et al. The ATLAS Experiment at the CERN Large Hadron Collider. JINST 3: S08003.
(1998) Accomando E, Troncon C, et al. Physics with e+ e- colliders. Physics Report C, 299, 1. Amsterdam (Olanda).

Katia Varani
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STEM area: Biomedical sciences and biotechnology

Competences: cellular pharmacology

Keywords: anxiety, cancer, chronic diseases on an inflammatory basis, chronic pain, Huntington's korea, multiple sclerosis

Region: Emilia-Romagna


Position/Role

Associate Professor of Pharmacology,Department of Medical Sciences and University Center for Studies on Gender Medicine, University of Ferrara, Italy

Professional career

After graduating in Biological Sciences at the University of Ferrara in 1988, she continued her studies obtaining a Ph.D. in Cellular and Molecular Pharmacology in 1996. After that, she became Assistant Researcher in Pharmacology and from 2009 to date is Associate Professor in Pharmacology, Department of Medical Sciences, University Center for Studies on Gender Medicine, University of Ferrara.

Scientific results

The research themes of Katia Varani and her group are well represented by the pharmacological, biochemical and molecular study of adenosine receptors that have an important role in the central nervous system, the cardiovascular system and the immune response. The interaction of adenosine receptors is studied in neurodegenerative diseases (Huntington's chorea, Parkinson's disease and Multiple Sclerosis), in chronic and neuropathic pain, in cardiovascular disorders such as hypertension and heart failure, inflammatory diseases and cancer. Some studies show that A3 adenosine receptors represent a possible therapeutic target for preventing the development of mesothelial pleural tumors after exposure to asbestos. Other studies have shown that stimulated A2A adenosine receptors have an anti-inflammatory role in chronic inflammatory diseases, such as rheumatoid arthritis. Recently, preclinical studies have shown that allosteric modulators of A1 adenosine receptors are endowed of analgesic and anxiolytic properties. The development of new potential drugs acting on adenosine receptors could constitute a valid and innovative pharmacological tool that could be very useful in clinical therapy.

Editorial work and publications

Katia Varani contributed of 232 full scientific publications on international refereed journals with impact factor (total IF: 1234). She is included in the Top Italian Scientists of the VIA Academy with a ranking of 68. Google Scholar: H index = 61; Sum of the citations: 10288.

5 Selected Publications:

 

-Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K (2018). Pharmacology of Adenosine Receptors: The State of the Art. Physiology Review 98(3):1591-1625.

-Borea PA, Gessi S, Merighi S, Vincenzi F, Varani K (2017). Pathologic overproduction: the bad side of adenosine. British J Pharmacology174:1945-1960.

-Tabrizi M, Baraldi PG, Borea PA, Varani K (2016). Medicinal chemistry, pharmacology, and potential therapeutic benefits of cannabinoid CB2receptor agonists. Chemical Reviews 116:519-560.

- Borea PA, Gessi S, Merighi S, Varani K (2016). Adenosine as a multi-signalling guardian angel in human diseases: when, where and how does it exert its protective effects? Trends in Pharmacological Sciences, S0165-6147(16)00041-9.

- Preti D, Baraldi PG, Moorman AR, Borea PA, Varani K (2015). History and perspectives of A2Aadenosine receptor antagonists as potential therapeutic agents. Medicinal Research Reviews, 35(4):790-848.

Ersilia Vaudo
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STEM area: Physics

Competences: astrophysics, cosmology, international relations, strategy

Keywords: diversity and inclusion, ESA (European Space Agency), international relations, space programs, strategy, women and science, Women in STEM

Region: ABROAD


Position/Role

Chief Diversity Officer, European Space Agency

Professional career

Ersilia Vaudo Scarpetta has a degree in physics from Università La Sapienza in Rome, where she started working at the Department of Cosmology on experiments on the measurement of anisotropy in the cosmic background radiation. She has been working at the European Space Agency since 1991 and she is currently Chief Diversity Officer. 

During her career at ESA, she held several positions i.a. in international relations, elaboration of high level strategies, preparation of decisions at Member States’ ministerial meetings, network with think tanks. She supported the creation of the European Space Policy Institute in Vienna. She participated to the formulation of the first ESA Exploration programme, worked as coordinator of Science and Human Spaceflight activities and had the responsibility as Executive Secretary of the Science and Technology Advisory Group on Exploration in charge of selecting experiments for exploration missions, including ExoMars. She spent four years at the ESA Washington Office ensuring relations with NASA and US stakeholders, and was Member of the Board of Directors of Women in Aerospace USA. Currently she is member of the International Women’s Forum, of the Women’s Forum for the Economy and Society Daring Circle, and of Women in Aerospace – Europe.

Scientific results

Ersilia Vaudo has a long experience in space programmes, in particular in science and explorations, European space strategy, relationships with NASA. In addition, she works to encourage the advancement of girls and women in STEM education and careers and to promote the values of diversity and inclusiveness.

Editorial work and publications

2019 – Più donne di scienza per vincere la sfida della competitività - Il Sole 24 Ore 

2018 – Simply into science, how to tear down the STEM gender- Worldcrunch.com 

2018 – La Scienza delle Donne- Wired 2018 –Why women in space are developing science ‘superpowers’, becoming smarter and shooting higher, Womenthology.co.uk

2017 – Lunar glow: what is driving the new space race to the Moon, Worldcrunch.com 

2016 – Space and its Links to Economic Theory and Public Support, in Theorising Space, Washington DC:Rowman & Littlefield 

2016 – Il futuro del lavoro ai tempi del determinismo tecnologico, Il Menabo’ di Etica ed Economia 

2015 – The role of space in support of the common objectives of the European Nordic countries, 66th International Astronautical Congress, Jerusalem, Israel

2014 – Rosetta, the comet Hunter, Il Menabo’ di Etica ed Economia 

2002 –Assessing ESA’s Current Voting Rules and Practice and Potential Weighted Voting Systems in the Perspective of Enlargement, ESA Bulletin

2015 - TEDX Bari, 2015: L’Universo è resiliente?

2015 - TEDX Roncade, 2015: La sfida della conoscenza

2018 - TEDX Matera, 2018: Donne, Scienza e Superpoteri

2019 - TEDX THBrandenburg: La prima volta che..

Awards and prizes

1983 - Accademia dei Lincei Fellowship Enrico Persico

1986 - Amelia Earhart Fellowship in recognition of distinctive merit in Astrophysics studies

2016 - Awarded Premio Cajeta in the category Science and Scientific Research

2019 - Nomination for the European Diversity Awards in the category Head of Diversity of the Year 

2019 - Included in the list of Unstoppable Women from StartupItalia which acknowledges women’s commitment to technology in Italy

2019 - Lectio Magistralis at Opening 157th Academic Year Politecnico di Milano

Marinela Vavla
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STEM area: Psychology and neurosciences

Competences: clinical neurology, neuroimaging in neurodenegeration

Keywords: cerebellar ataxia, cerebral palsy in children, clinical assessment, clinical trial conduction, Friedreich's Ataxia, glycogen storage disorders, Hereditary Spastic Paraplegia, motor control, motor rehabilitation, movement disorders, neuromodulation, rare neurodegenerative disorders

Region: Apulia


Position/Role

Lecturer at MSc Neuroscience at King’s College, University of London. Resident in Respiratory Medicine at the University of Foggia.

Professional career

After graduating in Medicine and Surgery in 2007 from the University of Florence, she undertook a scientific training path with a Master of Science in Neuroscience at the Institute of Psychiatry, Psychology & Neuroscience of the King's College, University of London. In the years 2012-2015 she obtains a PhD in Developmental Medicine and Programming Sciences at the University of Padua and works at the IRCCS "Eugenio Medea" in Conegliano Veneto. In 2019-2020 she completes a Post-Doctoral Fellowship at the University of Padua. In 2021 she begin her residency training in Respiratory Medicine at the University of Foggia. Since 2010 she has been a lecturer for the Master of Neuroscience programme at IOPPN of King's College in London.

Scientific results

Since the beginning of her research in the neuroscience field, she has approached the study of the neurological disorders, starting with Multiple Sclerosis and Amyotrophic Lateral Sclerosis with clinical and laboratory approaches. While carrying out a project on SOD-1 toxicity in experimental models and acquiring laboratory technical skills, she also developed a particular interest in movement disorders.

The main research project that she has explored is the study of cerebellar ataxias, and in particular of Friedreich's ataxia. She has explored the clinical aspects and also the brain volume, diffusion and cerebral-cerebellar activation characteristics in this pathology with advanced neuroimaging techniques. This research was followed by an important clinical and neuroradiological follow-up which also generated an international collaboration for rare cerebellar diseases (ENIGMA-Ataxia).

Furthermore, she has been interested into exploring and developing treatment proposals, such as experimental clinical studies and their design, application of neuromodulation and rehabilitation strategies in Friedreich’s Ataxia.

She is engaged in postgraduate teaching and in the supervision of graduate students within health professional areas.

The results of her research have been published in international scientific journals and have been presented as contributions in national and international conferences.

Editorial work and publications

[2020] Vavla M, Arrigoni F, Toschi F, Peruzzo D, Maria Grazia D'angelo MG, Gandossini S, Russo A, Diella E, Tirelli S, Salati R, Rufini A, Condo I, Testi R, Martinuzzi A. Sensitivity of neuroimaging indicators in monitoring the effects of interferon gamma treatment in Friedreich’s Ataxia. Front. Neurosci. doi: 10.3389/fnins.2020.00872.

[2021] Pizzighello S, Vavla M, Minicuci N, Pellegri A, Martinuzzi A. Trends observed in bilateral cerebral palsy during a thirty-year period: A cohort study with an ICF-based overview. Pediatr Neonatol. Feb 5:S1875-9572(21)00018-8. doi: 10.1016/j.pedneo.2021.01.016. Online ahead of print. PMID: 33663988

[2020] Scalco RS, Lucia A, Santalla A, Martinuzzi A, Vavla M, Reni G, Toscano A, Musumeci O, Voermans NC, Kouwenberg CV, Laforêt P, San-Millán B, Vieitez I, Siciliano G, Kühnle E, Trost R, Sacconi S, Stemmerik MG, Durmus H, Kierdaszuk B, Wakelin A, Andreu AL, Pinós T, Marti R, Quinlivan R, Vissing J; EUROMAC Consortium. Data from the European registry for patients with McArdle disease and other muscle glycogenoses (EUROMAC). Orphanet J Rare Dis. Nov 24;15(1):330. doi: 10.1186/s13023-020-01562-x. PMID: 33234167

[2020] Vavla M, Montanaro D, Pizzighello S, Frijia F, Arrigoni F, Baratto A, Piccoli G, Paparella G, Martinuzzi A. Brain Magnetic Spectroscopy Imaging and Hereditary Spastic Paraplegia: A focused Systematic Review on Current Landmarks and Future Perspectives. Front Neurol. Jul 14;11:515. doi: 10.3389/fneur.2020.00515. eCollection 2020. PMID: 32765386

[2020] Montanaro D, Vavla M, Frijia F, Aghakhanyan G, Baratto A, Coi A, Stefan C, Girardi G, Paparella G, De Cori S, Totaro P, Lombardo F, Piccoli G, Martinuzzi A. Multimodal MRI longitudinal assessment of White and Grey Matter in different SPG types of Hereditary Spastic Paraparesis Front Neurosci. Jun 4;14:325. doi: 10.3389/fnins.2020.00325. eCollection 2020. PMID: 32581663

[2020] Paparella G, Vavla M, Bernardi L, Girardi G, Stefan C, Martinuzzi A. Efficacy of a combined treatment of botulinum toxin and intensive physiotherapy in Hereditary Spastic Paraplegia. Front. Neurosci. Doi: 10.3389/fnins.2020.00111

[2020] Vavla M, D'Angelo MG, Arrigoni F, Toschi N, Peruzzo D, Gandossini S, Russo A, Diella E, Tirelli S, Salati R, Scarpazza P, Luffarelli R, Fortuni S, Rufini A, Condò I, Testi R, Martinuzzi A. Safety and efficacy of interferon γ in friedreich's ataxia. Mov Disord. 35(2):370-371. doi: 10.1002/mds.27979. Epub 2020 Jan 13. PMID: 31930551

[2020] Vavla M, Paparella G, Papayannis A, Pascuzzo R, Girardi G, Pellegrini F, Capello G, Prosdocimo G, Martinuzzi A. Optical Coherence Tomography in a cohort of genetically defined Hereditary Spastic Paraplegia: A brief research report. Front. Neurol. | doi: 10.3389/fneur.2019.01193

[2019] Vavla M, Paparella G, Merotto V, Comiotto J, Piai J, Martinuzzi A. Combining Transcranial Direct Current Stimulation and Intensive Physiotherapy in Patients with Friedreich’s Ataxia: A Pilot Study. Acta Scientific Neurology 2.1: 03-10.

[2018] Vavla M, Arrigoni F, Nordio A, De Luca A, Pizzighello S, Petacchi E, Paparella G, D'Angelo MG, Brighina E, Russo E, Fantin M, Colombo P, Martinuzzi A. Functional and Structural Brain Damage in Friedreich's Ataxia. Front Neurol. Sep 6;9:747. doi: 10.3389/fneur.2018.00747. ECollection 2018. PMID: 30237783.

[2016] Martinuzzi A, Montanaro D, Vavla M, Paparella G, Bonanni P, Musumeci O, Brighina E, Hlavata H, Rossi G, Aghakhanyan G, Martino N, Baratto A, D'Angelo MG, Peruch F, Fantin M, Arnoldi A, Citterio A, Vantaggiato C, Rizzo V, Toscano A, Bresolin N, Bassi MT. Clinical and Paraclinical Indicators of Motor System Impairment in Hereditary Spastic Paraplegia: A Pilot Study. PLoS One. Apr 14;11(4): e0153283. doi: 10.1371/journal.pone.0153283.

[2014] Aghakhanyan G, Martinuzzi A, Frijia F, Vavla M, Hlavata H, Baratto A, Martino N, Paparella G, Montanaro D. Brain White Matter Involvement in Hereditary Spastic Paraplegias: Analysis with Multiple Diffusion Tensor Indices.AJNR Am J Neuroradiol. Aug;35(8):1533-8. doi: 10.3174/ajnr.A3897.

Awards and prizes

In 2011 Marinela Vavla won a PhD scholarship and in 2019 another Post-Doctoral research scholarship, both at the University of Padua. During 2015-2020 she received research fundings from the Association Ogni Giorno per Emma to carry out research in the field of cerebellar ataxias and Friedreich's Ataxia.

 

Paola Velardi
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STEM area: Computer science

Competences: computer technology, electronic engineering

Keywords: artificial intelligence, coronavirus, machine learning, mathematical models, natural language, social networks, web, web semantics, women and science

Region: Lazio


Position/Role

President of the Degree Course and Professor of Computer Science at the “Sapienza” University of Rome.

Professional career

After graduating in Electronic Engineering at the “Sapienza” University of Rome in 1978, she worked as a researcher at the Ugo Bordoni Foundation until 1982. In 1983 she was a visiting scholar at Stanford University and, from 1984 to 1986, was a researcher at the IBM science centre in Rome. From 1986 to 1996 she is associate professor at the Faculty of Engineering of the University of Ancona. Since 1996 she is a professor at the Computer Science Department of the S.MM.FF.NN faculty of the “Sapienza” University of Rome. In 2001 she won a first class competition and became a full professor at the same university, where from 2011 to 2013 she was President of the Degree Course in Computer Science, a position she took on again in November 2016. Since 2013 she has been responsible for the Master’s degree course in Computer Science, distance learning. She teaches Machine Learning and Web and Social Information Extraction at the Master’s degree in Computer Science (in English), and from 2017, also the Business Intelligence course in Management Master's Degree taught in English. She is involved in gender issues, and she has been coordinating the NERD orientation project for six years in order to increase the number of girls enrolled in computer courses.

Scientific results

In the first years of scientific activity, Paola Velardi was involved in Computer Architecture and Reliability to then address her studies to Artificial Intelligence. Later, her main research interests concerned natural language processing, machine learning, semantic modeling and semantic web, i.e. the transformation of the web into an environment where published documents are associated with information and data which specify the semantic context in a format suitable for interrogation and interpretation (for example, through search engines) and, more generally, for automatic word processing. More recently, she has been involved in the analysis of social networks, applying her studies to user profiling, the detection of trending topics (topics of discussion that become popular among users of social networks), and the study of female leadership in social networks companies, epidemiological surveillance and e-health.

Editorial work and publications

She is author of over 150 national and international publications, including:

(2021) Aragona D, Podo L, Prenkaj B, Velardi P. CoRoNNa: A Deep Sequential Framework to Predict Epidemic Spread. SAC '21 Proceedings of the 36th Annual ACM Symposium on Applied Computing. 3.

(2016) Stilo G, Velardi P. Hashtag Sense Clustering based on Temporal Similarity. Computational Linguistics, 43-1. 

(2016) Stilo G, Velardi P. Efficient Temporal Mining of Micro-blog Texts and its application to Event Discovery. Data Mining and Knowledge Discovery, 30(2):372-402.

(2015) Faralli S, Stilo G, Velardi P. Recommendation of micro-blog users based on hierarchical interest profiles. Social Network Analysis and Mining, 5, 25. 

(2015) Gesualdo F, Stilo G, D’Ambrosio A, Carloni E, Pandolfi E, Velardi P, et al. Can Twitter be a source of information on allergy? Correlation of pollen counts with tweets reporting symptoms of allergic rhinoconjunctivitis and names of antihistamine drugs. PloS One, 10(7):e0133706 

(2015) Faralli S, Stilo G, Velardi P. Large Scale Homophily Analysis in Twitter using a Twixonomy. Proceedings of International Joint Conference on Artificial Intelligence (IJCAI 2015) Buenos Aires. 

(2015) Faralli S, Stilo G, Velardi P. What Women Like: A Gendered Analysis of Twitter Users' Interests based on a Twixonomy. Ninth International AAAI Conference on Web and Social Media Workshop: Wikipedia, a Social Pedia: Research Challenges and Opportunities, Oxford. 

(2015) Di Tommaso G, Stilo G, Velardi P. Women leadership in enterprise social networks: A SNA toolkit to foster the emergence of informal leaders in organizations. International Conference on Information Society (i-Society 2015), IEEE, London. 

(2014) P. Velardi P, G. Stilo G, E. Tozzi E, Gesualdo F. Twitter mining for fine-grained syndromic surveillance. Artificial Intelligence in Medicine, 61(3):153-63. 

(2013) Velardi P, S. Faralli S, Navigli R. OntoLearn Reloaded: A Graph-based Algorithm for Taxonomy Induction. Computational Linguistics, 39(3), MIT Press.

(2013) Gesualdo F, Stilo G, Agricola E, Gonfiantini MV, Pandolfi E, Velardi P, Tozzi AE. Influenza-like illness surveillance on Twitter through automated learning of naïve language. PLoS One, 8(12):e82489.

Awards and prizes

She participated as a partner, associate partner or coordinator in various national and European projects. Among others, the national projects (MIUR law 297) CHAT, on multimodality topics, and LC3, a public-private research laboratory on the topic of communication of cultural knowledge; the SimiTur 2.0 (POR FESR 2007/2013 - CO-RESEARCH) regional projects on the theme of tourism; PARTICIPATE (Research Projects presented by Research Institutes LR 13/2008) on topics of e-collaboration and participatory interfaces in the tourist / cultural field; HomeCare4All (POR FERS Lazio 2007/2013) on issues of public health and multilingual interaction with users; and finally Fiordaliso (POR FERS Lazio 2007/2013) on the topic of analysis of female leadership in corporate social networks. She was a member of the governing committee of the European INTEROP Network of Excellence (2003-2007), on enterprise interoperability issues and the scientific committee of the "EU Virtual Laboratory for Enterprise Interoperability", an European research institute legally established in Belgium in 2007. She is a reviewer of the European community, reviewer and member of the most important conferences and journals on the topics of interest (ACL, EACL, EMNLP, ESWC, IJCAI, ICWSM, TKDD, TKDE, CL, AIIM, BIBM, WWW, etc.). She is Associate Editor of Knowledge and Information Systems.

 

 

Margherita Venturi
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STEM area: Chemistry

Competences: supermolecular electrochemistry, supermolecular photochemistry

Keywords: chemical computers, disclosure, energetic conversion, energy, molecular machines, nanosciences, nanotechnologies, shows

Region: Emilia-Romagna


Position/Role

Full professor of General Chemistru at University of Bologna

Professional career

After graduating in Chemistry at the University of Bologna in 1971, she continued her education first as a fellow, then a contractor and finally a researcher at the Faculty of Pharmacy at the University of Bologna until 1992. In the same year she became associate professor in the faculty of Mathematical Sciences , Physics and Natural of the same university, and is confirmed again in 1995. Since 2005 she is full professor of General Chemistry of the University of Bologna.

Scientific results

From 1972 to 1991 she worked at National Research Council of Bologna where her main research activity was focused on the field of Radiation Chemistry. In particular, she studied the electron-transfer processes involved in model systems for the conversion of solar energy in chemical energy. Her present research activity is in the field of Supramolecular Photochemistry and Electrochemistry; specifically she is involved in the realization of systems made by two or more molecules capable of performing useful functions. The aims of the research are the following. 1. The desing and construction of chemical systems where the molecular components display changes in their relative positions as a result of some external stimulus, that can be photochemical, chemical and electrochemical in nature. Such systems are called molecular machines and their importance is testified by the fact that this research topic was awarded the Nobel Prize in Chemistry 2016. 2. The design and construction of systems capable of transferring, switching, collecting, storing, and elaborating photochemical, chemical and electrochemical signals. Up to now several systems of this kind have been obtained, like molecular antennae, wires, plug/socket and extension devices. The results of her research are of great importance in the fields of nanosceince and nanotechnology; for example the developed systems can lead to the construction of molecular devices able to convert solar energy in chemical energy and to elaborate information (chemical computer); they can also find applications in the field of medicine, for example, to develop drug delivering systems that can open new perspectives to treat tumors.

Editorial work and publications

She is co-author of more than 250 scientific papers, including several reviews, published in the most relevant international journals. Five of them are listed below.

1.    (2015) D’Agostino S, Bergamini G, Ceroni P, Comotti A, Sozzani P, Bassanetti I, Grepioni F, Hernandez TM, Silvi S, Venturi M, Credi A. Photoinduced reversible switching of porosity in molecular crystals based on star-shaped azobenzene tetramers. Nature Chemistry, 7:634-640.

2.    (2015) Ragazzon G, Baroncini M, Silvi S, Venturi M, Credi A. Light-powered autonomous and directional molecular motion of a dissipative self-assembling system. Nature Nanotechnology, 10:70-75.

3.    (2008) Balzani V, Credi A, Venturi M. Photochemical conversion of solar Energy. ChemSusChem, 1:26-58.

4.    (2008) Balzani V, Credi A, Venturi M. Molecular Devices and Machines – Concepts and Perspectives for the Nanoworld. Wiley-VCH: Weinheim, 1-546.

5.    (2006) Balzani V, Clemente-León M, Credi A, Ferrer B, Venturi M, Flood A H, Stoddart J F. Autonomous artificial nanomotor powered by sunlight. Proc. Natl. Acad. Sci. USA, 103:1178-1183.

Awards and prizes

In 2014 she received the Gold Medal Gabriello Illuminati from the Italian Chemical Society because of her contribution and involvement in teaching and spreading Chemistry as author of articles and books, as coordinator and partner of national and European projects, and as organizer of seminars, scientific exhibits, and teacher training courses. In addition, the medal recognized the fact that in 2000 she began to organize at the Department of Chemistry “Giacomo Ciamician” a show entitled Sounds, Lights, Colors and Other Special Effectsduring which the attending students (from primary to high schools) and citizens can see chemical demonstrations and understand the importance, utility, and beauty of Chemistry.

 

 

Antonella Viola
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STEM area: Biomedical sciences and biotechnology

Competences: biology, immunology

Keywords: cancer cure, coronavirus, Covid-19, immune system, immunology, immunotherapy, inflammation, stamina cells

Region: Veneto


Position/Role

Full Professor of General Pathology at the University of Padua

Scientific Director at Istituto di Ricerca Pediatrica (IRP), Padua

Professional career

After graduating in Biological Sciences at the University of Padua in 1991, prof. Viola continued her education with a PhD in Evolutionary Biology, which she obtained in 1995 at the same university. She then joined the scientific community of the Basel Institute of Immunology (BII), first as visiting scientist and then as BII scientific member. In 2001 she went back to Padua as assistant professor and head of the Immunology Laboratory at the Venetian Institute of Molecular Medicine (VIMM). In 2007, she moved to Milan to direct the Adaptive Immunity Laboratory at the Humanitas Research Center. In 2014 she became full professor of General Pathology at the University of Padua and in 2017 scientific director of the Pediatric Research Institute (IRP). She has been a member of the scientific committee of the Italian Association for Cancer Research (AIRC) and a reviewer for the European Commission (FP7 and ERC). She has coordinated international (Prostate Cancer Research Program), European (E-rare) and national projects (AIRC, Telethon, MIUR, Ministry of Health) and has been partner of two ambitious projects of the European community, SYBILLA and MERLIN.

Scientific results

After the studies on T lymphocytes (capable of killing virus-infected cells or helping B cells in the production of antibodies), prof. Viola has expanded her research in the field of tumor immunology and, subsequently, of mesenchymal stromal cells. More recently, she decided to focus on the study of macrophages (cells responsible for phagocytizing pathogens and involved in all inflammatory processes) and she proposed to the European Commission the project “STePS”, which was awarded the ERC Advanced Grant. The results of her research are of great importance in basic research but also in other areas, from cancer immunotherapy (ability to exploit our own immune system to directly and focused treat certain diseases) to autoimmune diseases (diseases caused by improper activation of our immune system).

Editorial work and publications

Author of numerous scientific publications, including:

(2011) Molon B, Ugel S, Del Pozzo F, Soldani C, Zilio S, Avella D, De Palma A, Mauri PL, Monegal A, Rescigno M, Savino B, Colombo P, Jonjic N, Pecanic S, Lazzarato L, Fruttero R, Gasco A, Bronte V, Viola A. Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells. The Journal of Experimental Medicine,208(10):1949-62.

(2010) Contento RL, Campello S, Trovato AE, Magrini E, Anselmi F and Viola A. Adhesion shapes T cells for prompt and sustained T cell receptor signaling. EMBO Journal, 29:4035-47.

(2008) Viola A & Luster AD. Chemokines and Their Receptors: Drug Targets in Immunity and Inflammation. Annual Review of Pharmacology and Toxicology, 48:171-197.

(2007) Viola A & Gupta N. Tether and Trap: Regulation of membrane rafts by actin-binding proteins. Nature Reviews Immunology, 7:889-96.

(2006) Campello S, Lacalle RA, Bettella M, Manes S, Scorrano L & Viola A. Orchestration of leukocyte chemotaxis by mitochondrial dynamycs. The Journal of Experimental Medicine, 203:2879-2886.

(2006) Tavano R, Contento RL, Baranda SJ, Soligo M, Tuosto L, Manes S & Viola A. CD28 interaction with filamin-A controls lipid raft accumulation at the T cell immunological synapse. Nature Cell Biology, 8:1270-1276.

(2005) Molon, Gri G, Bettella M, Goumez-Mouton C, Lanzavechia A, Martinez-A C, Manes S & Viola A. T cell costimulation by chemokine receptors. Nature Immunology, 6:465-71.

(2005) Bronte V, Kasic T, Gri G, Gallana K, Borsellino G, Marigo I, Battistini L, Iafrate M, Prayer-Galetti T, Pagano F & Viola A. Boosting anti-tumor responses of T lymphocytes infiltrating human prostate cancers. The Journal of Experimental Medicine, 201:1257-68.

(1999) Viola A, Schroeder S, Sakakibara Y & Lanzavecchia A. T lymphocyte costimulation mediated by reorganization of membrane microdomains. Science, 283:680-2.

(1996) Viola A & Lanzavecchia A. T cell activation determined by T cell receptor number and tunable thresholds. Science, 273:104-6.

Awards and prizes

In 2010 she won the Cancer Reseach Institute Investigator Award (CRI, New York) and in 2008 the "Donne Eccellenti" award and the prestigious "Chiara D'Onofrio" award. In 2013 Antonella Viola received the ERC Advanced Grant and a € 2.5 million financing to continue her STEPS project. In 2016 she was elected member of the European Molecular Biology Organization (EMBO), a prestigious recognition that was preceded in 2006 by the appointment as EMBO Young Investigator.

Lucia Votano
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STEM area: Physics

Competences: experimental physics of astroparticlesm, experimental physics of particles

Keywords: astroparticles, gran sasso workshops, infn, juno, neutrinos, nuclear physics, particle physics, particles, work

Region: Lazio


Position/Role

Research Director, associate to Frascati National Laboratory of INFN (Istituto Nazionale di Fisica Nucleare).

 

Professional career

Born in Calabria, Italy, in November 1947, LV graduated with summa cum laude in Physics at University 'La Sapienza' (Roma) in 1971.

She became staff research scientist at INFN - Frascati National Laboratory (LNF) in 1975, Senior Researcher in 1988 and Research Director in 2000.

As an experimental particle and astroparticle physicist, she has been active at Frascati National Laboratory, CERN-Geneva, DESY-Hamburg, Gran Sasso Laboratory, performing physics studies as well as constructing and running large detector systems.

From 1999 through 2004 she was the Director of the LNF Research Division.

From 2009 to 2012 she was the Director of the Gran Sasso Laboratory (LNGS) in Italy, first woman to be appointed in this position.

LNGS is the largest (17800 m2) underground laboratory in the world for astroparticle physics and the most advanced in terms of length, complexity and completeness of its infrastructures, hosting 20 cutting edge international experiments. More than 950 scientists from 29 different Countries take part in the LNGS experimental activities and constitute its large international scientific community.

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Scientific results

The research activity of Lucia Votano concerns astroparticle physics, a field at the intersection of astronomy, particle physics and cosmology, addressing questions relating to the micro-cosmos of elementary particles and their fundamental interactions and, at the same time, the macro-cosmos, the birth and evolution of the universe.

In particular her main interest turned to neutrinos, the most mysterious, enigmatic and mystifying particle among the ones that make up the Universe. The neutrino’s interaction with matter is truly tiny and one the most intriguing results of the last decades is the evidence, by measuring the phenomenon of neutrino oscillations, that they do have a mass, although very small.

In order to properly comprehend the mechanism of the oscillation; various neutrino sources, both natural (the Sun or other stars) and artificial (particle accelerators or nuclear power plants) can be used.

LV started working for the Large Volume Detector (LVD) experiment at LNGS, designed to detect neutrinos from gravitational stellar collapses within our entire Galaxy.

Afterwards she has joined the OPERA experiment that has provided the first and firm direct evidence of the muon-neutrino oscillation into tau-neutrino. The detector was located in the underground Gran Sasso Laboratory, 730 km away from the neutrino source at Geneva and exposed to the CNGS (Cern neutrinos to Gran Sasso) pure muon-neutrino beam.

The study of the intrinsic properties of neutrino is of prime interest in particle physics and has provided by now the only direct and undisputed experimental evidence of the inadequacy of the successful Standard Model of elementary particles and interactions.

Presently she is member of JUNO (Jiangmen underground Neutrino Observatory) Collaboration, a giant multi-purpose neutrino experiment under construction in Kaiping, Jiangmen, Guangdong Province (South China), 53 km far from two nuclear power plants, and aiming at the determination of the neutrino mass hierarchy. The 20 kton liquid scintillation detection volume, together with the excellent energy resolution, will allow JUNO to address many physics goals related to the observations of neutrino events of astrophysical and terrestrial origin

Editorial work and publications

The research activities have resulted in about 300 papers on international scientific journals and in presentations at international conferences. Among them:


(2018) M. Reguzzoni et al., GIGJ: a crustal gravity model of the Guangdong Province for predicting the geoneutrino signal at the JUNO experiment.
arXiv:1901.01945 [physics.geo-ph].

(2018) N. Agafonova et al. Final Results of the OPERA Experiment on nt Appearance in the CNGS Neutrino Beam.
Phys.Rev.Lett. 120 (2018) no.21, 211801, Erratum: Phys.Rev.Lett. 121 (2018) no.13, 139901.

(2018) N. Agafonova et al. Final results of the search for nm  n oscillations with the OPERA detector in the CNGS beam.
JHEP 1806 (2018) 151.

(2018) N. Agafonova et al. Measurement of the cosmic ray muon flux seasonal variation with the OPERA detector.
arXiv:1810.10783 [hep-ex].

(2018) F. Riggi et al. Time and orientation long-distance correlations between extensive air showers detected by the MRPC telescopes of the EEE Project
Nuovo Cim. C40 (2018) no.6, 196.

(2018) M. Grassi et al. Charge reconstruction in large-area photomultipliers
JINST 13 (2018) no.02, P02008.

(2018) A. Paoloni, A. Mengucci, M. Spinetti, M. Ventura, L. Votano.

Streamer studies in Resistive Plate Chambers

arXiv:1806.03443 [physics.ins-det].

(2016) Fengpeng An et al. Neutrino Physics with JUNO.
J.Phys. G43 (2016) no.3, 030401.

(2015) N. Agafonova et al. Discovery of $\tau$ Neutrino Appearance in the CNGS Neutrino Beam with the OPERA Experiment
Phys.Rev.Lett. 115 (2015) no.12, 121802.
(2015) N. Agafonova et al. Limits on muon-neutrino to tau-neutrino oscillations induced by a sterile neutrino state obtained by OPERA at the CNGS beam
JHEP 1506 (2015) 069.

 

Lucia Votano has also published two scientific books for general public:

“Il fantasma dell’universo-Che cos’è il neutrino”, Collana La Città della Scienza, Carocci editore 2015 and 

“La via della seta. La fisica da Enrico Fermi alla Cina” Collana i Dialoghi, Di Renzo editore 2017.

In April 2010 has been awarded by the President of the Italian Republic of the official title of

 ” Commendatore al merito Della Repubblica Italiana” for scientific services.

 

Ann Zeuner
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STEM area: Biomedical sciences and biotechnology

Competences: cellular biology, molecular biology

Keywords: cancer, cancer stem cells, chemotherapy, disclosure, school, stamina cells

Region: Lazio


Position/Role

Biotechnology Group Leader, Department of Oncology and Molecular Medicine, Istituto Superiore di Sanità (National Institute of Health), Rome, Italy

Professional career

Dr. Ann Zeuner is a 49 years old researcher who dedicated more than half of her life to cancer research. Combining her two passions, biology and science communication (for which she obtained a MS at the International School of Advanced Studies in Trieste)

Scientific results

Dr. Zeuner carries out a biomedical research of high translational relevance flanked by an active commitment in research dissemination. Dr. Zeuner's major achievements reflect her constant effort to translate basic research in useful tools to improve the knowledge and treatment of cancer.

1) Mirroring the success of a professional life devoted to cancer research, the PI has published 48 papers in  high level journals including Nature, Science, Blood, Cancer Research, Cell Stem Cell. Importantly, 13 of these publications (excluding reviews) are research papers where the PI is first, last or corresponding author, indicating a profound personal commitment in the projects.

2) The PI dedicated great effort to scientific challenges having practical implications for the treatment and quality of life of cancer patients. Specifically, she has patented a new method to prevent chemotherapy-induced anemia and thrombocytopenia in cancer patients (Zeuner A. et al. Pat. N. US7994125 B2, 8/9/2011) and she recently developed a new class of compounds with anti-cancer stem cell activity and minimal toxicity against normal tissues (Zeuner A. et al. Pat. N. 102014902292046, approved Jan. 2017).

3) The PI has a strong commitment in promoting international cooperation among research and clinical groups in the field of oncology. For this reason, she was appointed by the Italian Ministry of Health as leader of the COLOMED (COLOrectal cancer in MEDiterranean countries) project, with the goal of creating a network of research and clinical centers working on colorectal cancer (CCR) in Mediterranean countries. COLOMED (www.colomed.it) has been actively involved in creating strategic partnerships, broadening scientific cooperation, promoting the investments of resources in CCR research and fostering the transfer of technology and personnel among Mediterranean centers.

4) The PI strongly believes in the importance of science communication as a fundamental link between academic research, patients and the general public. She takes an active part in this commitment by writing articles for journals and magazines and by providing support to educational and charity initiatives in the field of cancer and cord blood donation.

5) The PI is particularly devoted to scientific dissemination toward schools. Every year she hosts in her laboratory high-school students within Ministry of Education projects (PON and Alternanza Scuola-Lavoro) and she published a book for schools on stem cells (“Le cellule staminali”, 80 pages, edited by the italian National Institute of Health and freely distributed on print and web, http://www.iss.it/binary/publ/cont/Dispensa_11_1_web.pdf), which encountered a considerable success not only among students but also among the general public. The book was reprinted several times and is now undergoing an updated re-edition together with publication of an English version.

Editorial work and publications

(2017)   Colorectal cancer: towards new challenges and concepts of preventive healthcare. Colace L, Boccia S, De Maria R, Zeuner A. Ecancer medical science. 2017 Nov 28;11:ed74. doi: 10.3332/ecancer.2017.ed74. eCollection 2017.

(2015) Francescangeli F, Contavalli P, Gambara G, De Angelis ML, Baiocchi M, Pagliuca A, Fiorenzano A, Prezioso C, Boe A, Todaro M, Stassi G, Castro NP, Watanabe K,         Salomon DS, De Maria R, Minchiotti G, Zeuner A. Dynamic regulation of the cancer stem cell compartment by Cripto-1 in colorectal cancer. Cell Death Differ. 2015 Oct;22(10):1700-13.

(2014)  Zeuner A, Todaro M, Stassi G, De Maria R. Colorectal Cancer Stem Cells: From the Crypt to the Clinic. Cell Stem Cell. 2014 Dec 4;15(6):692-705.

(2014) Zeuner A, Francescangeli F, Contavalli P, Zapparelli G, Apuzzo T, Eramo A, Baiocchi M, De Angelis ML, Biffoni M, Sette G, Todaro M, Stassi G, De Maria R. Elimination of quiescent/slow-proliferating cancer stem cells by Bcl-XL inhibition in non-small cell lung cancer. Cell Death Differ. 2014, 105.

(2013) Todaro M, Turdo A, Bartucci M, Iovino F, Dattilo R, Biffoni M, Stassi G, Federici G, De Maria R, Zeuner A. Erythropoietin activates cell survival pathways in breast cancer stem-like cells to protect them from chemotherapy. Cancer Res. 2013 Nov 1;73(21):6393-400.

(2012)  Francescangeli F, Patrizii M, Signore M, Federici G, Di Franco S, Pagliuca A, Baiocchi M, Biffoni M, Vitiani LR, Todaro M, De Maria R, Zeuner A. Proliferation State and Polo-like Kinase1 Dependence of Tumorigenic Colon Cancer Cells. Stem Cells. 2012 Sep;30(9):1819-30.

(2011) Bartucci M, Dattilo R, Martinetti D, Todaro M, Zapparelli G, Di Virgilio A, Biffoni M, De Maria R, Zeuner A. Prevention of chemotherapy-induced anemia and thrombocytopenia by constant administration of stem cell factor. Clin. Cancer Res. 2011 Oct 1;17(19):6185-91.

(2009) Zeuner A., Pedini F., Francescangeli F., Signore M., Girelli G., Tafuri A., De Maria R. Activity of the BH3 mimetic ABT-737 on polycythemia vera erythroid precursor cells Blood, 2009, vol 113, pag. 1522-5.

(1999) De Maria R*, Zeuner A*, Eramo A, Domenichelli C, Bonci D, Grignani F, Srinivasula SM, Alnemri ES, Testa U, Peschle C. Negative regulation of erythropoiesis by caspase-mediated cleavage of GATA-1. Nature, 1999, vol. 401, pag. 489-493. *Equal contribution

(1997) De Maria R, Lenti L, D'Agostino F, Zeuner A, Tomassini B, Rippo MR, Testi R. Requirement for GD3 ganglioside in CD95- and ceramide- induced apoptosis. Science, 1997, vol. 277, pag. 1652-1655.

 

Monica Zoppé
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STEM area: Biomedical sciences and biotechnology

Competences: grafical representation of cellular, molecular and structural biology, interdisciplinary research, molecular biology, structural biology, women and science

Keywords: 3D Computer Graphic, gender and science, molecular animation, structural biology

Region: Lombardy


Position/Role

Researcher at Institute of BioPhysics of the Italian National Council of Research, Milan

Professional career

After graduating in Biology, in 1987 in Milan, she moves for a series of post-docs in different laboratories in Italy (CNR, ICGEB of Trieste) and abroad (UK, Biochemistry Department at the University of Birmingham, and USA, at the Salk Institute, in the laboratory of Inder Verma).

After 15 years in several laboratories, she gets a position as a researcher at the Institute of Clinical Physiology (IFC) of the Italian National Research Council (CNR) of Pisa. Here after a short period, following a serious accident, of which she is not responsible, she is forced to leave the laboratory.

She then embarks on a new phase of her scientific career, dedicating to Biological Representation, with the idea of virtually recreating the cellular world using the techniques developed in the field of Computer Graphics (film, video and video games). Today the discipline is recognized as 'Molecular Graphics'. In 2006 she founded the Scientific Visualization Unit at IFC, and obtained the first funding, with which she obtained the scientific results listed below. In 2019 she moves to Milan at the Institute of BioPhysics of the CNR. In this period, she starts a collaboration with groups of Cuban computer scientists, bioinformaticians and biologists, with whom she has active and funded projects, always related to the visualization, in this case of the Dengue virus.

Today Monica Zoppé is considered a pioneer of the 'Art and Science of Scientific Visualization', and is recognized as one of the major theorists of the field, often invited to mostly international conferences and meetings.

In parallel, she also actively participates in the Donne e Scienza (Women and Science) association, she is a member of the board since few years. It is in the context of this activity that she contributed substantially to the organization of the European #WeTooInScience congress, held in Pisa in 2018.

Scientific results

The results obtained in the experimental biology field are documented in the publications available online on the ORCID website.

For the works in the 'Molecular Graphics' field, the main result is the transposition into a graphic system, therefore visible, of the molecular world which is a very rich world, indeed in cells operate specific and different forces: for example, gravity does not count while thermal vibration counts, and many of the forces at play can be calculated as potentials (electrical, lipophilic, osmotic and thermodynamic flows), for which we have no visual perception. 

In detail, the main results obtained in this area can be summarized as follows:

  • development of the theoretical and operative bases of the new discipline, scientific visualization, dedicated to the narrative of the cellular and molecular biology
  • foundation of the interdisciplinary working group Scientific Visualization: www.scivis.it;
  • development and release of multiple versions of BioBlender, a tool that allows one to introduce rigorous scientific data in Blender, one of the most advanced Computer Graphics tools, and the only completely Open Source, developed for cinema and video games;
  • Production of a series of short cellular animations, all freely available on the website www.scivis.it and on the major channels, which have obtained important awards both in the scientific, cinematographic and technical fields (see list);
  • introduction to the concept of a visual code with which to represent invisible, not unknown, elements.

Editorial work and publications

[2019] Zoppè, Monica G. Improving Gender Diversity in ScienceIn #WeTooInScience - Sexual Harassment in Higher Education Institutions and Research Organizations, CNR-IRPPS e-Publishing 235–41. Rome, Italy.

[2019] Zoppè, M., Loni,T., Carlone,I., Cianchetta,S.. Making of The Dark Anim: Technical and Scientific Notes. In 2019 International Conference on Cyberworlds (CW), 45–52. Kyoto, Japan: IEEE, 2019

[2018]  Caudai, C., Salerno, E., Zoppè, M. and Tonazzini, A.  ChromStruct 4: A Python Code to Estimate the Chromatin Structure from Hi-C Data. IEEE/ACM Transactions on Computational Biology and Bioinformatics. 

[2017] Zoppè, M  Towards a perceptive understanding of cellular biology.  Nat Meth 14(7): 662-665 .

[2015] Zoppè, M  La sindrome dell’impostore: Non sono davvero brava come sembra. In: Scienza, genere e società. Prospettive di genere in una società che si evolve. S. Avveduto, M. L. Paciello, T. Arrigoni, C. Mangia, L. Martinelli (eds.). Roma: CNR-IRPPS e-Publishing. 

[2015] Zoppè, M. and Loni, T. The Representation of Electrostatics for Biological Molecules. In: W. Rocchia and M. Spagnuolo (eds.), Computational Electrostatics for Biological Applications, Springer International, Switzerland. 215-225.

[2014] Zoppè, M. Comunicare l’invisibile. La rappresentazione visiva di concetti biofisici / Communicating the Invisible. The Visual Representation of Biophysical Concepts. In: Scrittura e immagini nel dominio della scienza / Text and Image in the sicentific realm. A cura di/Edited by: R. Falcinelli, A. Filippini, G. Liberti, L. Perondi e L. Romei. Progetto Grafico, 25:50 

[2012] Andrei, R., Callieri, M., Zini, M.F., Loni, T., Maraziti, G. and Zoppè, M. Intuitive representation of surface properties of proteins using BioBlender. BMC Bioinformatics, 13(Suppl 4):S16

[2011] Zoppè, M. Vedere l'invisibile. Le Scienze – Italian version of Scientific American. Roma, 515: p. 64-9. 

Selection of VIDEO

[2015] The Dark Anim, (5', 23''). A description of the serotoninergic synapse, and its activity in the healthy and depressed states. With subtitles in English, French and Italian.

[2012] TSH receptor on Red Blood cells, 2011 (3', 48''). Thyrotropin is a hormone that elicit response from thyroid gland. However, its receptor is also found on the surface of red blood cells. After binding, the dimeric receptor splits into two subunits, each of which leaves the lipid raft to associate with other proteins of the cellular surface. 

[2010] PROTEIN EXPRESSIONS - Study N.3 (5', 01''). The video, also produced in 3D, is the final one in a series of tests in the development of BioBlender. It shows several moments of cellular life, from the surface to the cytoplasm and back to cell periphery and out. Watched >70.000 times (Vimeo statistics).

Awards and prizes

The video PROTEIN EXPRESSIONS- Study n.3  has been awarded in several occasions:

[2009] Suzanne Award of the  Blender Foundation, Amsterdam 2009

[2010] Prize of the Jury, at Melzo Film Festival, Milan. Italy. 2010

[2011] Selected as finalist at DogVille-Viladecan Film Festival, Barcelona, Spain. 2011

[2012], First prize.  NANOPLANET was awarded the First Prize in the  ‘Art&Science contest’ at BioPhysical Society meeting, San Francisco (CA. USA).

[2013]  The video The Challenge of HIV Research, reached the Fourth classification in the 'AutoPACK visualization contest’ by the Computer Graphics Society – Autodesk.

[2018] Invitation to the restricted Shonan Meeting on ‘Web Molecular Graphics: Emerging

Technologies & Standards’, Japan. 

Francesca Zoratto
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STEM area: Biomedical sciences and biotechnology

Competences: behavioural neuroscience, ethology

Keywords: animal behaviour, basic research, collective anti-predator behaviours, gamble, human behaviour, preclinical research, predation, risk appetite

Region: Lazio


Position/Role

Researcher (fixed term) at the Centre for Behavioural Sciences and Mental Health of the Italian National Institute of Health (Istituto Superiore di Sanità; Rome, Italy)

Professional career

My main expertise pertains to the study of animal behaviour and closely related disciplines (e.g. psychobiology, neuroethology, psychopharmacology). I graduated at the University of Parma (Italy) in 2008 with a thesis in Ethology and subsequently obtained a PhD in Ethology at the University of Florence (Italy) in 2013 with a research project on impulsivity and gambling proneness in rats. In 2014 I had a 14-month contract at the Bambino Gesù Paediatric Hospital (Rome, Italy) within the research area “Multifactorial diseases and complex phenotypes”. The following year I received a scholarship from the Noopolis Foundation to perform research activities at the section of Behavioural Neuroscience of the Italian National Institute of Health (Istituto Superiore di Sanità; Rome, Italy). Thanks to a L’ORÉAL-UNESCO For Women in Science 2016 Award, I carried out research activities as a postdoctoral research fellow at the Unit of Cognitive Primatology and Primate Centre, where I focused my research on the social modulation of risky decision-making in non-human primates and rodents. Currently, I am working as a research scientist at the Centre for Behavioural Sciences and Mental Health of the Italian National Institute of Health (Istituto Superiore di Sanità; Rome, Italy), within a group that has a consolidated experience and tradition in the behavioural phenotyping of animal models, with a special focus on critical periods such as infancy and adolescence.

Scientific results

My primary interest is the study of animal behaviour in a functional and evolutionary perspective. For my research projects, I have dealt with multidisciplinary research topics at the intersection between laboratory work and natural settings, studying different species and combining data from different fields.

Currently, my research is mainly devoted to the development and validation of animal models of human neurobehavioural disorders, with particular reference to conduct and impulse control disorders and behavioural addictions (i.e. gambling disorder). The propensity to risk and gamble is not only found in human beings, and the study of animal behaviour can help to better understand the psychobiological mechanisms on which our addictions are based. Increasing the knowledge in this field is intended to provide more elements of understanding to the medical community, but also to develop proposals for the political class to study more effective strategies in the prevention and treatment of pathological gambling.

 

Editorial work and publications

Up to now (January 2019), I have co-authored about 40 papers in international peer-reviewed scientific journals including:

-          Zoratto F., Sbriccoli M., Martinelli A., Glennon J.C., Macrì S., Laviola G. 2018. Intranasal oxytocin administration promotes emotional contagion and reduces aggression in a mouse model of callousness. Neuropharmacology 143:250-267

-          Zoratto F., Oddi G., Gori E., Micucci A., De Petrillo F., Paglieri F., Adriani W., Laviola G, Addessi E. 2018. Social modulation of risky decision-making in rats (Rattus norvegicus) and tufted capuchin monkeys (Sapajus spp.). Behavioural Brain Research 347:37-48.

-          Zoratto F., Cordeschi G., Grignani G., Bonanni R., Alleva E., Nascetti G., Mather J.A., Carere C. 2018. Variability in the “stereotyped” prey capture sequence of male cuttlefish (Sepia officinalis) could relate to personality differences. Animal Cognition 21(6):773-785.

-          Zoratto F.*, Romano E.*, Pascale E., Pucci M., Falconi A., Dell’Osso B., Maccarrone M., Laviola G., D’Addario C., Adriani W. 2017. Down-regulation of serotonin and dopamine transporter genes in individual rats expressing a gambling-prone profile: a possible role for epigenetic mechanisms. Neuroscience 340:101-116. (*equally contributed to this work as co-first authors)

-          Canese R.*, Zoratto F.*, Altabella L., Porcari P., Mercurio L., De Pasquale F., Butti E., Martino G., Lacivita E., Leopoldo M., Laviola G., Adriani W. 2015. Persistent modification of forebrain networks and metabolism in rats following adolescent exposure to a 5-HT7 receptor agonist. Psychopharmacology 232(1):75-89. (*equally contributed to this work as co-first authors)

-          Zoratto F., Laviola G., Adriani W. 2013. Gambling proneness in rats during the transition from adolescence to young adulthood: a home-cage method. Neuropharmacology 67:444-454.

-          Koot S.*, Zoratto F.*, Cassano T., Colangeli R., Laviola G., van den Bos R., Adriani W. 2012. Compromised decision-making and increased gambling proneness following dietary serotonin depletion in rats. Neuropharmacology 62(4):1640-1650. (*equally contributed to this work as co-first authors)

-          Zoratto F., Carere C., Chiarotti F., Santucci D., Alleva E. 2010. Aerial hunting behaviour and predation success by peregrine falcons Falco peregrinus on starling flocks Sturnus vulgaris. Journal of Avian Biology 41(4):427-433.

 

Awards and prizes

Francesca Zoratto has received numerous awards and recognitions for her academic career. In 2016 she received a L’ORÉAL-UNESCO For Women in Science 2016 Award from the “Fondation L’ORÉAL” in collaboration with L’ORÉAL Italia and the Italian National Commission for UNESCO.