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Results: 23


Patrizia Azzi
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STEM area: Physics

Competences:

Keywords:

Region: Veneto


Position/Role

Staff researcher for INFN(Istituto Nazionale di Fisica Nucleare), Italy, Section of Padua

 

Professional career

After completion of her Physics Diploma at the University of Padua in 1992, she pursued a PhD in Physics in 1996. Immediately after she wins a grant for continuing her studies as a post-doctoral scientist at the INFN Section in Padua. In 2008, 2012 and 2014 is awarded several grants for collaboration as a Scientific Associate at the CERN laboratory in Geneva(CH) and the Fermilab National Laboratory in Chicago (USA). Currently she is leading studies for the prospects physics measurements in the context of future projects for new particle colliders to be realised after the end of the LHC. 

Scientific results

In 1996, as a member of the CDF collaboration, observes for the first time the decay of the top quark (the heaviest fundamental particle in the Standard Model) and measures its production rate and and mass developing original analysis methods of background estimate from real data. In 2004 becomes a member of the CMS collaboration at the LHC of CERN laboratory in Geneva (CH). She has participated to the discovery of the Higgs boson in the role of responsabile of the data quality to be used for the analysis. Throughout her career Patrizia Azzi has focused her interest on particle physics and their properties to explain the fundamental law of physics. Azzi has been also coordinating several research projects: from 2002-2004 she has been leading the Top physics group for the CDF collaboration at Fermilab to plan and realise the measurements of the top quark properties during the Run 2 of the Tevatron collider, coordinating a group of about 200 physicist from all countries. As a member of the CMS experiment she has been coordinating various groups, among which the "Physics Performance and Dataset" that insured the data quality for physics in 2012/2013 and the physics group "B2G" that focuses on searches for new physics beyond the Standard Model in 2014/15. Currently she is leading the physics group that studies the future prospects for the project High Luminosity LHC that will start in 2024. 

--questo sarebbe aggiunto per aggiornamento ma non c'e' in italiano, non so se volete metterlo-- 

Patrizia Azzi is also an active proponent of the Future Circular Collider project (FCC) where she studies in particular the potential for the most precise measurement of the top quark mass at a new lepton collider.

 

Editorial work and publications

She is author of vaste number of publication national and international, we quote here some of the most relevant: 


(2016) CMS Collaboration, Khachatryan S, [...] Azzi P, et al. Search for vectorlike charge 2/3 T quarks in pp collisions at √s=8 TeV.Physical Review D, 93:012003. 
(2014) CMS Collaboration. Search for top-quark partners with charge 5/3 in the same-sign dilepton final state.Physical Review Letters, 112:171801. 
(2014) Bicer M, [...] Azzi P, et al. First Look at the Physics Case of TLEP. The Journal of High Energy Physics, 01:164. 
(2012) The CMS Collaboration. Observation of a new boson at a mass of 125 GeV with the CMS experiment at the LHC.Physics Letters B, 716:30-61. 
(2009) CMS Tracker Collaboration, Adam W, [...] Azzi P, et al. Performance studies of the CMS Strip Tracker before installation.Journal of Instrumentation, 4. 
(1999) CDF Collaboration, Abe F, [...] Azzi P, et al. Measurement of the top quark mass with the Collider Detector at Fermilab.Physical Review Letters, 82:271-276. 
(1997) CDF Collaboration, Abe F, [...] Azzi P, et al. First observation of the all hadronic decay of t pairs. Physical Review Letters, 79:1992-1997. 
(1995) CDF Collaboration, Abe F, [...] Azzi P, et al. Observation of top quark production in p collisions. Physical Review Letters, 74:2626-2631. 
(1994) CDF Collaboration, Abe F, [...] Azzi P, et al. Evidence for top quark production in pcollisions at √s = 1.8 TeV.Physical Review Letters, 73:225-231. 
(1994) Amidei D, Azzi P, et al. The Silicon Vertex Detector of the Collider Detector at Fermilab. Nuclear Instruments and Methods in Physics Research Section A, 350:73-130.

Awards and prizes

2014-2015: Scientific Associate  at CERN(Switzerland)

2013 European Physical Society High Energy and Particle Physics Prize, for an outstanding contribution to High Energy Physics, awarded to the ATLAS and CMS collaborations, “for the discovery of a Higgs boson, as predicted by the Brout-Englert-Higgs mechanism” 

2012-2013     LHC Physics Center Fellow at Fermilab (USA)

 

2008-2009: Scientific Associateat CERN(Switzerland) 

 

Daniela Bortoletto
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STEM area: Physics

Competences:

Keywords:

Region: ABROAD


Position/Role

Head of Particle Physics at the University of Oxford (September 2018-to present)

Professional career

Daniela Bortoletto graduated in Physics from the University of Pavia, Italy in 1982. She earned her MA (1986) and PhD (1989) from Syracuse University. In 1989 she joined the Faculty of Purdue University as Postdoctoral Research Associate (1989-1992), Assistant Professor (1992-1995), Associate Professor (1995-2001), and Full Professor (2001). She became the Edward M. Purcell Distinguished Professor of Physics in 2010. In 2013 she joined the University of Oxford where she is now the Head of the sub department of particle physics. Daniela is passionate about increasing female participation in Physics and other sciences. She has enabled efforts aimed at giving young women the resources, motivation, and confidence to pursue careers in Physics. This includes the creation of the Purdue Women in Physics Organization, the development of Purdue Sciencescape, and leadership in the APS Conference Undergraduate Women in Physics (CUWiP). She has taken CUWiP in the UK where the conference has been extraordinarily successful.

Scientific results

She has made important contributions to heavy flavour physics at CLEO (Cornell, USA) and CDF (Fermilab USA). She is a co-discoverer of the Higgs boson (CERN, 2012) and the top quark (CDF, Fermilab, 1995). She is currently studying the properties of the Higgs boson and searching for new physics at the LHC with the ATLAS experiment at CERN. She is also searching for new physics in very rare decays of muons with the mu3e experiment at the Paul Sherrer Institut. Daniela played an important role in the construction of the muon system for the CLEO detector, the SVX II silicon system for CDF, and the CMS Forward Pixel detector.  She was the US CMS Upgrade coordinator for over 7 years and led the activities of over 40 US Universities for the phase 1 and phase 2 upgrade of CMS. She is currently participating in the construction of the ATLAS ITK for the High Luminosity LHC, high voltage CMOS sensors, and ultra-radiation hard silicon sensors. She is the Deputy Scientific Coordinator of the Advanced European Infrastructures for Detectors at Accelerators (AIDA 2020)

Editorial work and publications

Editor of Nuclear Instrument and Methods. Author of over 1500 publications.

 

Awards and prizes

She is a fellow of the American Physical Society (2004), American Association for the Advancement of Science (2013) and the Institute of Physics (2015). She has received the Purdue University Ruth and Joel Spira for Excellence in Undergraduate Education (2004). She was awarded the Alfred P. Sloan Fellowship (1994), the Early Career Award of the US National Science Foundation (1997) and the US NSF Career Advancement Award (1994). She has been a member of the UK STFC grants panel (2018), the UK STFC Detectors Strategic Review Panel (2018), US Particle Physics Projects Prioritization Panel (P5, 2005-2007, 2008, 2010), the High Energy Physics Advisory Panel (HEPAP, 2005-2008) to the US DOE and NSF, and the Mathematical and Physical Science Advisory Committee (MPSAC, 2008-2014) to the NSF and the chair of the Fermilab Program Advisory Committee (2014-2017).

Maria Antonia Brovelli
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STEM area: Physics

Competences:

Keywords:

Region: Lombardy


Position/Role

Full Professor and former Vice Rector of Politecnico di Milano for the Como Campus.

Professional career

After obtaining a degree in Physics at the University of Milan in 1986, she continued her education with a PhD in Geodetic and Topographical Sciences that she obtained in 1991 at the Interuniversity Consortium of Milan, Turin and Pavia. From 1992 to 1994, she was Researcher at the National Institute of Geophysics and Volcanology, where she helped create the International Geoid Service (IGeS) of the International Geodesy Association (IAG) and became part of the IGeS Bulletin committee, becoming its chief editor. In 1994, she became a researcher at the Politecnico di Milano, and four years later an associate professor. In 1997, she founded and coordinated the Geomatics Laboratory at the Como Campus of the Politecnico di Milano. From 2006 to 2011, she was a lecturer of GIS at the Federal Polytechnic of Zurich (ETH). Since 2010, she has been Full Professor of Digital Mapping and Geographic Information Systems (GIS) at the Politecnico di Milano and from 2011 to 2016 she was Vice Rector of Politecnico for the Como Campus.

Scientific results

After obtaining a degree in Physics at the University of Milan in 1986, she continued her education with a PhD in Geodetic and Topographical Sciences that she obtained in 1991 at the Interuniversity Consortium of Milan, Turin and Pavia. From 1992 to 1994, she was Researcher at the National Institute of Geophysics and Volcanology, where she helped create the International Geoid Service (IGeS) of the International Geodesy Association (IAG) and became part of the IGeS Bulletin committee, becoming its chief editor. In 1994, she became a researcher at the Politecnico di Milano, and four years later an associate professor. In 1997, she founded and coordinated the Geomatics Laboratory at the Como Campus of the Politecnico di Milano. From 2006 to 2011, she was a lecturer of GIS at the Federal Polytechnic of Zurich (ETH). Since 2010, she has been Full Professor of Digital Mapping and Geographic Information Systems (GIS) at the Politecnico di Milano and from 2011 to 2016 she was Vice Rector of Politecnico for the Como Campus.

Editorial work and publications

Maria Antonia Brovelli is editor of the Applied Geomatics journal published by Springer, co-author of three textbooks on the statistical processing of data, of a volume on orthophotos, i.e. geometrically correct and georeferenced aerial and satellite imagery, and digital terrain models, and author of over 150 scientific publications including:

(2018) Brovelli MA, Zamboni G, A new method for the assessment of spatial accuracy and completeness of OpenStreetMap building footprints, ISPRS International Journal of Geo-Information 7(8),289.

 

(2016) Brovelli MA, Minghini M, Zamboni G, Public Participation in GIS via Mobile Applications, ISPRS Journal of Photogrammetry and Remote Sensing 114, pp. 306-315.

 

(2015) Brovelli MA, Molinari ME, Hussein E, Chen J, Li R. The First Comprehensive Accuracy Assessment of GlobeLand30 at a National Level: Methodology and Results. Remote Sensing, 7(4):4191-4212. 


(2008) Brovelli MA, Crespi M, Fratarcangeli F, Giannone F, Realini E. Accuracy assessment of high-resolution satellite imagery orientation by leave-one-out method. ISPRS Journal of Photogrammetry and Remote Sensing, 63(4):427-440. 


(2004) Brovelli MA, Cannata M, Longoni UM. LIDAR Data Filtering and DTM Interpolation Within GRASS. Transactions in GIS, 8(2), 155-174. 



Awards and prizes

In September 2015 she was awarded the Sol Katz Award 2015 for her contribution to Free Software and Open Source Geospatial during the FOSS4G 2015 conference in Seoul, South Korea. Maria Antonia Brovelli was one of the Directors of OSGeo (International GIS Open Foundation). She is  Chair of the working group IV / 4 "Collaborative Crowdsourced Cloud Mapping (C³M)" of the International Society of Photogrammetry and Remote Sensing (ISPRS), member of UN-GGIM Italy, Chair of the "Capacity Building" working group of the United Nations "UN OpenGIS", Deputy chair and member of the International Task Team (single woman) with the task of supporting the United Nations for the geospatial aspects (UN-GGIM). She was co-organizer of the annual "Europa NASA World Wind Challenge" event, which involved students and professionals in developing applications based on the virtual globe of NASA. Finally, she is a member of ACEO, the Advisory Committee for Earth Observation (ACEO), which is the main interpreter of the views and needs of the European scientific community on access to space experimentation and data exploitation in Earth science programs.

Marta Burgay
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STEM area: Physics

Competences:

Keywords:

Region: Sardinia


Position/Role

Researcher at the Cagliari Astronomical Observatory of the Italian National Intitute for Astrophysics (INAF)

Professional career

After graduating in Astronomy at the University of Bologna in 2000, Marta Burgay continued her studies at the same university where she obtained her PhD in 2004. A few months later she became a researcher at the INAF - Cagliari Astronomical Observatory, where she works on compact objects (studying ultra-dense stars). In particular she is an expert in observations and studies of radio pulsars (one of the manifestations of the compact neutron stars, so called because they are observed through pulses of radiation appearing at short regular intervals). Since 2012 she is part of the scientific  team operating the new 64-m Sardinia Radio Telescope. She is also a member of the European and the International Pulsar Timing Array experiments for the detection of gravitational waves from supermassive black holes, and of the GRAWITA (GRAvitational Wave Inaf TeAm) collaboration to search for the electromagnetic counterparts of gravitational wave events.

Scientific results

The scientific activity of Marta Burgay is focused mainly on neutron star studies and in particular on observations and investigations of pulsars. Her name is linked to the important discovery of the binary system J0737-3039A / B, the first and, to date, the only system formed by two pulsars. Thanks to its many peculiarities, thisdouble pulsar represents a unique laboratory in several fields (nuclear physics, plasma physics, relativistic gravity...): in the field of general relativity, for example, the study of the times of arrival of the pulses of the two stars allowed her team to test the validity of the theory of general relativity with a precision of 99.95%. Continued observations of this system, still underway, will allow to further improve this limit and to test alternative theories of gravity.
Since 2008 Marta Burgay has been part of the High Time Resolution Universe Survey project for pulsars and transients searches, and since 2013 of the SUPERB survey (Survey for Pulsars and Extragalactic Radio Bursts). Thanks to these projects almost 200 new pulsars have been discovered, including more than 30 extremely fast rotating millisecond pulsars, a magnetar (a different type of neutron star with a huge magnetic field) emitting radio waves, a pulsar with a "diamond" planet, and a new class of transient sources, the Fast Radio Bursts (FRBs), of yet unknown origin.

Editorial work and publications

Marta Burgay is (co-)author of 140 refereed articles published in international journals (including 4 in Nature and 5 in Science) that have received a total of more than 9000 citations. She is (co-)author of 22 telematic scientific communications (Astronomer's Telegram, GCN Circulars) and (co-)author of 58 conference proceedings. She is editor in chief of a volume of conference proceedings.

[2016] Keane E F, Johnston S, Bhandari S, Barr E, Bhat NDR, Burgay M, Caleb M, Flynn C, Jameson A, Kramer M, Petroff E, Possenti A, van Straten W, Bailes M, Burke-Spolaor S, Eatough RP, Stappers BW, Totani T, Honma M, Furusawa H, Hattori T, Morokuma T, Niino Y, Sugai H, Terai T, Tominaga N, Yamasaki S, Yasuda N, Allen R, Cooke J, Jencson J, Kasliwal MM, Kaplan DL, Tingay SJ, Williams A, Wayth R, Chandra P, Perrodin D, Berezina M, Mickaliger M, Bassa C. The host galaxy of a fast radio burst, Nature, 530:453. [2013] Papitto A, Ferrigno C, Bozzo E, Rea N, Pavan L, Burderi L, Burgay M, Campana S, di Salvo T, Falanga M, Filipovic MD, Freire PCC, Hessels JWT, Possenti A, Ransom SM, Riggio A, Romano P, Sarkissian JM, Stairs I H, Stella L, Torres DF, Wieringa MH, Wong G F. Swings between rotation and accretion power in a binary millisecond pulsar, Nature, 501:517.
[2013] Thornton D, Stappers B, Bailes M, Barsdell B, Bates S, Bhat N D R, Burgay M, Burke-Spolaor S, Champion D J, Coster P, D'Amico N, Jameson A, Johnston S, Keith M, Kramer M, Levin L, Milia S, Ng C, Possenti A, van Straten W. A Population of Fast Radio Bursts at Cosmological Distances, Science, 341:53.
[2011] Bailes M, Bates SD, Bhalerao V, Bhat NDR, Burgay M, Burke-Spolaor S, D'Amico N, Johnston S, Keith MJ, Kramer M, Kulkarni SR, Levin L, Lyne AG, Milia S, Possenti A, Spitler L, Stappers B, van Straten, W. Transformation of a Star into a Planet in a Millisecond Pulsar Binary, Science, 333:1717.
[2006] Kramer M, Stairs IH, Manchester RN, McLaughlin MA, Lyne AG, Ferdman RD, Burgay M, Lorimer DR, Possenti A, D'Amico N, Sarkissian J M, Hobbs G B, Reynolds J E, Freire PCC, Camilo F. Tests of General Relativity from Timing the Double Pulsar, Science, 314:97.
[2003] Burgay M, D'Amico N, Possenti A, Manchester RN, Lyne AG, Joshi BC, McLaughlin MA, Kramer M, Sarkissian JM, Camilo F, Kalogera V, Kim C, Lorimer DR. An increased estimate of the merger rate of double neutron stars from observations of a highly relativistic system, Nature, 426:531.

Awards and prizes

Marta Burgay has received several awards, from the beginning of her career, in addition to covering important scientific and institutional roles. Her PhD thesis "The Parkes High-Latitude Pulsar Survey and the Discovery of the First Double Pulsar" received the 2005 Tacchini Prize of the Italian Astronomical Society (SAIt). In 2005 she also received the Descartes Prize for excellence in scientific collaborative research, as a member of the  group PulSE (Pulsar Science in Europe). In 2006 she was awarded with two important prizes, the Italian Society of General Relativity and Gravity Physics (SIGrav) Award for young researchers, and the International Union  for Pure and Applied Physics (IUPAP) Award for young physicists. In 2010 she won the Marsden Prize of the European Astrosky Network and the Vainu Bappu Award of the Astronomical Society of India. In 2011, the XXIII edition of the Marisa Bellisario Award dedicated to Women, Innovation and Human Capital assigned her a prize in the special awards section for young talents in research fields. In 2014 she was named "Chevalier de l'autonomie" of the Valle d'Aosta region and in 2015 she was designated "Sardinian woman of the year" by the Lyones Club of Cagliari. In 2017 the International Astronomical Union attributed to the asteroid n. 198634 the name Burgaymarta.

 

Laura Cadonati
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STEM area: Physics

Competences:

Keywords:

Region: ABROAD


Position/Role

Associate professor at theGeorgia Institute of Technology, Atlanta, United States.

Professional career

After graduating in Physics at the University of Milan, she continued her studies at the Princeton University, earning first a master's degree in 1998 and then a PhD in Physics in 2001. In the same year she became a post doc member at Princeton University, while, from 2002 to 2004 she held the same position at MIT (Massachusetts Institute of Technology).

In 2005 she was a research scientist at MIT, a role she held until 2007, when she became assistant professor at the University of Massachusetts Amherst. At the same university she worked as associate professor from 2012 until 2015. In 2014 she has been visiting scholar of Cardiff University for about six months. Since 2015 she is associate professor at the Georgia Institute of Technology.

Scientific results

Her scientific research concerns gravitational waves, specifically it deals with identifying, characterizing and interpreting those of short duration produced by huge astrophysical events such as the collapse of the supernova core or the collisions of black holes. In February 2016 a press conference was held to present the discovery (which took place in September 2015) which changed the way astrophysics is understood: Laura Cadonati and her international research team showed the existence of gravitational waves theorized by Albert Einsten in the Theory of General Relativity. The discovery was carried out by the LIGO gravitational observatory in the United States, in collaboration with an international team of a thousand scientists, including those responsible for the Italian experiment Virgo, in Cascina. Thanks to this result there will be new applications in the field of theoretical physics and applied physics: indeed the discovery is not limited to providing a better understanding of the theory of relativity, but it offers new possibilities for scientific research in the field of the birth of the universe, and of the understanding of the forces that surround us. Laura Cadonati’s previous research activity included the detection of solar neutrinos with the Borexino experiment and participation in the DarkSide project for the research of Dark Matter, both experiments took place in the Gran Sasso National Laboratories.

 

Editorial work and publications

Laura Cadonati is the author of numerous presentations of international conferences and workshops, as well as seminars and parts of university books such as:

 

“Listening to Space with LIGO.” L. Cadonati. State of the Universe 2007 - New Images, Discoveries, and Events, 2006 Springer Praxis Books, Popular Astronomy Series. Ratcliffe Editor.

 

Moreover, she is author of numerous scientific publications, including:

 

(2016) LIGO-Virgo Collaboration. GW151226: Observation of Gravitational Waves from a 22 Solar-mass Binary Black Hole Coalescence. Physical Review Letters ,116, 241103.

(2016) LIGO-Virgo Collaboration. Observation of Gravitational Waves from a Binary Black Hole Merger. Physical Review Letters, 116, 061102.

(2016) LIGO-Virgo Collaboration. Characterization of transient noise in Advanced LIGO relevant to gravitational wave signal GW150914. Classical & Quantum Gravity, 33, 134001.

(2016) LIGO-Virgo Collaboration. Observing gravitational-wave transient GW150914 with minimal assumptions. Physical Review D, 93, 122004.

(2016) LIGO-Virgo Collaboration. Prospects for Observing and Localizing Gravitational-Wave Transients with Advanced LIGO and Advanced Virgo. Living Reviews in Relativity, 19, 1.

(2014) Clark J, Bauswein A, Cadonati L, Janka HT, Pankow C, Stergioulas N. Prospects For High Frequency Burst Searches Following Binary Neutron Star Coalescence With Advanced Gravitational Wave Detectors. Physical Review D, 90, 062004.

(2014) LIGO-Virgo Collaboration. Methods and results of a search for gravitational waves associated with gamma-ray bursts using the GEO600, LIGO, and Virgo detectors. Physical Review D, 89,122004.

(2014) LIGO Scientific Collaboration, Virgo Collaboration, NINJA Collaboration. The NINJA-2 project: Detecting and characterizing gravitational waveforms modelled using numerical binary black hole simulations. Classical & Quantum Gravity, 31, 115004.

(2014) Borexino Collaboration. Neutrinos from the primary proton–proton fusion process in the Sun. Nature, 512, 383–386.

(2008) Borexino Collaboration. Direct Measurement of the Be 7 Solar Neutrino Flux with 192 Days of Borexino Data. Physical Review Letters, 101, 091302.

 

Awards and prizes

She has been working for the LIGO Scientific Collaboration since 2002. In 2010 she received the Career Award from the National Science Foundation (NSF), in the same year she was elected to the executive committee of the Topical Group on Gravitation of the American Physical Society. In 2014 she was chosen in the Chair-line of the APS Topical Group on Gravitation (currently called “Division of Gravity”). The following year she joined the Fellow of the American Physical Society. In 2016 she became a member of the Advisory Board of the Classical and Quantum Gravity Journal.

 

 

 

 

Patrizia Caraveo
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STEM area: Physics

Competences:

Keywords:

Region: Lombardy


Position/Role

She has the rank of Research Director  and works at the Istituto di Astrofisica Spaziale e Fisica Cosmica (INAF)  in Milano. She is also Professor of “Introduction to Astronomy” at the University of Pavia.

Professional career

PATRIZIA CARAVEO got her degree in physics in 1977 at the Milano University. Since 2002 she has the rank of Research Director  and works atthe Istituto di Astrofisica Spaziale e Fisica Cosmica (INAF)  in Milano. She is also Professor of “Introduction to Astronomy” at the University of Pavia

She took part in several international space missions dedicated to high energy astrophysics, starting from the European mission COS-B. Currently, she is involved in the exploitation of ESA’s Integral, of NASA’s Swift, of the Italian Agile and of the NASA Fermi missions, all fully operational in orbit. She also represents INAF within the CTA (Cherenkov Telescope Array) Collaboration Board.

Scientific results

She is a recognized leader in the study of neutron stars behavior at different wevelengths. Her work lead to the discovery (and to the understanding) of Geminga, the first radio quiet neutron star. Indeed, her career in astronomy was based in an interdisciplinary approach, using data from space and ground instruments.

Editorial work and publications

Her list of publication can be seen  at   http://www.iasf-milano.inaf.it/~pat/WEBpage/pat-pub.pdf .   It features:

Ø  432  papers published on international referee journals

Ø  150 conference papers (several invited papers)

Ø  Hundreds of  papers for the general public

Ø  2 books

However measured, her impact factor is very high. ADS, the system widely used by the astronomical community, quotes an h index >110, with more than 47,300 citations.

Awards and prizes

Owing to the Geminga success story, she won the Premio Nazionale Presidente della Repubblica in 2009. Moreover, she shared with her Swift, Fermi and Agile colleagues the Bruno Rossi prizeof the American Astronomical Society in 2007, 2011 and 2012

In 2014 she received the Outstanding Achievement Awardfrom the Women in Aerospace European Society and was included by Thomson Reuters in the list of Highly Cited Researchers for Space Science

In 2017 she was awarded the title of Commendatore dell’Ordine al Merito della Repubblica Italiana

 

Isabella Castiglioni
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STEM area: Physics

Competences:

Keywords:

Region: Lombardy


Position/Role

Researcher at the IBFM-CNR (Institute of Molecular Bio-images and Physiology - National Research Council) in Milan.

Professional career

After graduating in Physics at the University of Milan in 1993, she received a scientific education in the field of physics applied to medicine, (more recently to cultural heritage and the environment), in particular in applications of imaging diagnostics combined with advanced computational techniques. Since 1997 she is Researcher at the Institute of Molecular Bioimaging and Physiology of the National Research Council (IBFM-CNR), where, since 2011, she is also a member of the Council of the Institute. From 2010 to 2016 she was professor on contract at the University of Milano-Bicocca. She gained experience in research responsibility through the creation and management of her own research group at the IBFM-CNR, which was consolidated in 2011 in a research laboratory (Integration & Innovation Laboratory in Molecular Imaging, INLAB www.inlab.ibfm.cnr.it), which currently hosts 10 researchers with expertise in the field of bioimaging, computer science, biology and biotechnology.

 

Scientific results

She obtained important scientific results in: 1) physical characterization of diagnostic imaging systems, in particular positron emission tomography (PET), single photon emission tomography (SPECT), computed tomography (CT), magnetic resonance (MRI), fluorescence imaging/bioluminescence and near-infrared spectroscopy (fNIRS),                                  2) development of methods of acquisition and processing of diagnostic images for medical and cultural applications, 3) development of methods and models for the correction of physical effects, noise sources in diagnostic imaging studies (eg attenuation, dispersion, partial volume effect), 4) development of methods of quantification and extraction of characteristics from diagnostic images (for example analysis of statistical parametric mapping, radiomics, analysis of main components, machine learning), 5) creation of databases of synthetic medical images for the validation of processing methods and quantification of medical images. Since 2010 she has coordinated 13 scientific research projects financed on competitive tenders or through contracts, for a total non-repayable net grant of 2M €, and 12 research projects in agreement with IRCCS and Hospitals. She showed her research achievements in more than 50 seminars and lectures at national and international conferences, universities and research institutes. She is co-inventor of four softwares for the extraction and quantification of biomarker images and biomedical data in use at national and foreign health facilities. From 2012 to 2015 she was Mentor of two spin offs in the biomedical technology sector.

 

Editorial work and publications

She is credited with 112 scientific publications in ISI scientific journals, including:

Science, Nucleic Acids Research, Theranostics, European Journal of Nuclear Medicine and Molecular Medicine, Cerebral Cortex; she is in pole position (with the role of first, corresponding or last author) in more than 70% of her publications.

[2005] Berti A, Bottini G, Gandola M, Pia L, Smania N, Stracciari A, Castiglioni I, Vallar G. Shared cortical anatomy for motor awareness and motor control. Science, 309(5733):488-91.

[2014]Picchio M, Kirienko M, Mapelli P, Dell'Oca I, Villa E, Gallivanone F, Gianolli L, Messa C, Castiglioni I. Predictive value of pre-therapy (18)F-FDG PET/CT for the outcome of (18)F-FDG PET-guided radiotherapy in patients with head and neck cancer.Eur J Nucl Med Mol Imaging, 41(1):21-31.

[2015] Bertoli G, Cava C, Castiglioni I. MicroRNAs: New Biomarkers for Diagnosis, Prognosis, Therapy Prediction and Therapeutic Tools for Breast Cancer. Theranostics, 5(10):1122-43.

[2015] Salvatore C, Cerasa A, Battista P, Gilardi MC, Quattrone A, Castiglioni I; Alzheimer's Disease Neuroimaging Initiative. Magnetic resonance imaging biomarkers for the early diagnosis of Alzheimer's disease: a machine learning approach. Front Neurosci, 9:307. doi: 10.3389/fnins.2015.00307. eCollection 2015.

[2016] Colaprico A, Silva TC, Olsen C, Garofano L, Cava C, Garolini D, Sabedot TS, Malta TM, Pagnotta SM, Castiglioni I, Ceccarelli M, Bontempi G, Noushmehr H. TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data. Nucleic Acids Res, 44(8):e71. doi: 10.1093/nar/gkv1507.

[2017] Antunovic L, Gallivanone F, Sollini M, Sagona A, Invento A, Manfrinato G, Kirienko M, Tinterri C, Chiti A, Castiglioni I. [18F]FDG PET/CT features for the molecular characterization of primary breast tumors. Eur J Nucl Med Mol Imaging, 44(12):1945-1954.

[2017] Berti A, Della-Torre E, Gallivanone F, Canevari C, Milani R, Lanzillotta M, Campochiaro C, Ramirez GA, Bozzalla Cassione E, Bozzolo E, Pedica F, Castiglioni I, Arcidiacono PG, Balzano G, Falconi M, Gianolli L, Dagna L. Quantitative measurement of 18F-FDG PET/CT uptake reflects the expansion of circulating plasmablasts in IgG4-related disease. Rheumatology,56(12):2084-2092. 

[2018] Gargano M, Galli A, Bonizzoni L, Alberti R, Aresi N, Caccia M, Castiglioni I, Interlenghi M, Salvatore C, Ludwig N, Martini M. The Giotto's workshop in the XXI century: looking inside the “God the Father with Angels” gable. Journal of cultural heritage: https://doi.org/10.1016/j.culher.2018.09.016

[2019] Cantini L, Bertoli G, Cava C, Dubois T, Zinovyev A, Caselle M, Castiglioni I, Barillot E, Martignetti L. Identification of microRNA clusters cooperatively acting on Epithelial to Mesenchymal Transition in Triple Negative Breast Cancer. NAR, in press (Published on-line).

[2019] Musazzi L, Sala N, Tornese P, Gallivanone F, Belloli S, Conte A, Di Grigoli G, Fenghua C, Treccani G, Bazzini C, Castiglioni I, Nyengaard JR, Wegener G, Moresco RM, Popoli P. Acute inescapable stress rapidly increases synaptic energy metabolism in prefrontal cortex and alters working memory performance. Cerebral Cortex, in press.

Awards and prizes

From 2007 to 2009 she was Foreign Scientific Visitors Tutor for the International Atomic Energy Agency (IAEA). She is a scientific evaluator of research projects for International Institutions (Engineering in the Medical and Biology Society, Fundacao para a Cienca and in Technology FCT – Portugal, French Institute National du Cancer, Poland National Science Center, Horizon2020). She is a scientific reviewer in international scientific journals in the field of bioimaging and molecular diagnostics and carries out publishing activities, as Associate Editor and Guest Editor. In particular she was Lead Guest Editor of the Special Issue "Frontiers in Biomarkers for Theranostics" in Frontiers in Bioscience - Landmark, of the Special Issue "Frontiers from Radiomics in Molecular Imaging" in Contrast Media and Molecular Imaging, and of the Special Issue "Imaging biomarkers for the diagnosis and prognosis of neurodegenerative diseases” in Frontiers in Neuroscience.

 

 

 

Paola Corradi
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STEM area: Physics

Competences:

Keywords: smart city

Region: Lombardy


Position/Role

Full professor of pharmacology at the University of Bari

Professional career

After graduating in Medicine and Surgery at the University of Bari in 1979, she specialized in Neurology at the same university. She then obtained a scholarship from the Mario Negri Institute in Milan and, in 1984, moved as a researcher to Duke University Medical Center, Durham in the United States, in the group of Dr. R.J. Lefkowitz, Nobel Prize in Chemistry in 2012. Her academic career continued as Research Assistant Professor at the same Duke University and, since 1992, as professor of Pharmacology at the University of Lausanne in Switzerland. In 2007 she returned to Italy definitively and became professor of Pharmacology at the University of Bari.

Scientific results

Susanna Cotecchia has always been committed to basic research as an indispensable tool for understanding the mechanisms of disease and drug action. Her research focuses on the study of membrane receptors and site-directed mutagenesis, a particular technique used in molecular biology to study the structure-function relationship of proteins. This line of research aims to address the fundamental questions of molecular pharmacology, providing rapid screening methods and useful information to understand the mechanism of action of medicines. The goal is to build new molecules with selective and targeted pharmacological properties, the so-called drug design, which avoids side effects in the treatment of numerous diseases.

Editorial work and publications

She is the author of more than 100 national and international scientific papers, including:

 

(2006) Stanasila L, Abuin L, Diviani D, Cotecchia S. Direct interaction of ezrin with the alpha1b-adrenergic receptor regulates recycling of the internalized receptors. Journal of Biological Chemistry, 281:4354-63.

(2005) Hosoda C, Koshimizu TA, Tanoue A, Nasa Y, Oikawa R, Tomabechi T, Fukuda S, Shinoura H, Oshikawa S, Takeo S, Kitamura T, Cotecchia S, Tsujimoto G. Two alpha1-adrenergic receptor subtypes regulating the vasopressor response have differential roles in blood pressure regulation. Molecular Pharmacology, 67:912-22.

(2005) Novi F, Stanasila L, Giorgi F, Corsini GU, Cotecchia S, Maggio R. Paired activation of two components within muscarinic M3 receptor dimers is required for recruitment of beta-arrestin-1 to the plasma membrane. The Journal of Biological Chemistry, 280:19768-76.

(2005) Costa T and Cotecchia S. Historical Perspective: The discovery of inverse efficacy and the constitutive activity of GPCRs. Trends in Pharmacological Sciences.

(2005) Hosoda C, Tanoue A, Shibano M, Tanaka Y, Hiroyama M, Koshimizu TA, Cotecchia S, Kitamura T, Tsujimoto G, Koike K. Correlation between vasoconstrictor roles and mRNA expression of alpha(1) adrenoceptor subtypes in blood vessels of genetically engineered mice. British Journal of Pharmacology 146:456-66.

(2005) Sarang Z, Molnar P, Nemeth T, Gomba S, Kardon T, Melino G, Cotecchia S, Fesus L, Szondy Z. Tissue transglutaminase (TG2) acting as G protein protects hepatocytes against Fas-mediated cell death in mice. Hepatology 42:578-87.

(2004) Diviani D, Abuin L, Cotecchia S and Pansier L. Anchoring of both PKA and 14-3-3 inhibits the Rho-GEF activity of the AKAP-Lbc signaling complex, EMBO Journal 23:2811-20.

(2004) Cotecchia S, Stanasila L, Diviani D, Bjorklof K, Rossier O and Fanelli F. Structural determinants involved in the activation and regulation of G protein-coupled receptors: lessons from the alpha1-adrenegic receptor subtypes. Biology of the Cell, 96:327-33.

(2005) Zhang H, Cotecchia S, Thomas SA, Tanoue A, Tsujimoto G and Faber JE. Gene deletion of dopamine beta-hydroxylase and alpha1-adrenoceptors demonstrates involvement of catecholamines in vascular remodeling. American Physiological Society Journals, Heart and Circulatory Physiology, 287:H2106-H2114.

(2004) Townsend SA, Jung AS, Gillian Hoe YS, Lefkowitz RY, Khan SA, Lemmon CA, Harrison RW, Lee K, Barouch LA, Cotecchia S, Shoukas AA, Nyhan D, Hare JM and Berkowitz DE. Critical role for the alpha-1B adrenergic receptor at the sympathetic neuroeffector junction. Hypertension, 44:776-82.

 

Awards and prizes

Susanna Cotecchia received the award of the European Federation of Biochemical Societies (FEBS) in 1995. In 2001 she obtained the "Receptor Research Prize" of Perk.

 

 

Maria Cristina De Sanctis
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STEM area: Physics

Competences:

Keywords: dawn, exomars

Region: Lazio

Anna Di Ciaccio
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STEM area: Physics

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Region: Lazio

Simonetta Di Pippo
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STEM area: Physics

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Region: ABROAD

Roberta Fantoni
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STEM area: Physics

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Region: Lazio

Simonetta Gentile
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STEM area: Physics

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Region: Lazio

Sandra Leone
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STEM area: Physics

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Region: Tuscany

Rita Lorenzini
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STEM area: Physics

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Region: Emilia-Romagna

Giulia Manca
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STEM area: Physics

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Region: Sardinia

Giuseppina Micela
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STEM area: Physics

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Region: Sicily

Federica Migliardo
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STEM area: Physics

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Keywords: parkinson

Region: Sicily

Rosa Maria Montereali
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STEM area: Physics

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Region: Lazio

Paola Santini
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STEM area: Physics

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Region: Lazio

Sandra Savaglio
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STEM area: Physics

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Region: Calabria

Clara Troncon
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STEM area: Physics

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Region: Lombardy

Lucia Votano
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STEM area: Physics

Competences:

Keywords:

Region: Lazio