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Results: 149


Francesca Dominici
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STEM area: Biomedical sciences and biotechnology

Competences: biostatistics

Keywords: big data, environment, medical statistics, medicine, pollution, scientific data analysis, statistics, women

Region: ABROAD


Position/Role

Professor of Biostatistics at Harvard T.H. Chan School of Public Health

 

Professional career

After graduating in Statistics at La Sapienza University in Rome, she continued her education with a PhD at the University of Padua in 1997. After moving abroad, she became a Visiting Assistant Professor at the John Hopkins Bloomberg School of Public Health, homonymous university in Baltimore. She continued her academic career at John Hopkins and became Professor of the biostatistics department in 2007. She later moved to Harvard T.H. Chan School of Public Health, of the university of the same name, until she fulfilled the role not only of Professor of biostatistics but also of Senior Associate Dean for Research. Francesca Dominici's main interest is focused on the development of statistical methods for the analysis of large and complex data samples (Big Data), coming from heterogeneous sources, so that they can be combined to obtain important information that can be applied to different disciplines such as climate change, environmental sciences, cancer comparative research and public health policies.

 

Scientific results

Francesca Dominici is engaged in the development of new statistical methods for the analysis of large amounts of data (big data) detected and stored in massive databases (data warehouses) such as those of Medicare and SEER-Medicare. Her challenge is to develop new methods of Bayesian random inference (approach to statistical inference in which the probabilities of a given event happen are considered as levels of trust and no longer as frequencies), to overcome the analytical difficulties inherent in using large databases. This new approach allows Francesca Dominici, in collaboration with Harvard Medical School, to compare the efficacy in medical research in the treatment of glioblastoma (a tumor that develops between the glial cells, components of the nervous system along with neurons) and other tumors. Furthermore, her studies have directly influenced American policy on air quality and pollution, leading to the creation of new air and environmental quality standards.

Editorial work and publications

(2000) Dominici F, Samet JM, Zeger SL. Combining Evidence on Air pollution and Daily Mortality from the Twenty Largest US Cities: A Hierarchical Modelling Strategy with discussion. Journal of the Royal Statistical Society: Series A, 163(3):263-302.

(2000) Samet JM, Dominici F, Curriero F, Coursac I, Zeger SL, Fine Particulate Air Pollution and Mortality in 20 U.S. Cities: 1987-1994. New England Journal of Medicine, 343(24):1742-9.

(2004) Dominici F, McDermott A, Hastie T. Improved Semi-parametric Time Series Models of Air Pollution and Mortality. Journal of the American Statistical Association, 468:938-948.

(2006) Dominici F, Peng D, Bell M, Pham M, McDermott A, Zeger SL, Samet JM. Fine Particulates Air Pollution and Hospital Admission for Cardiovascular and Respiratory Diseases. Journal of the American Statistical Association, 295:1127-1135.

(2006) Peng R, Dominici F, Zeger SL. Reproducible Epidemiological Research. American Journal of Epidemiology, 163:783-789.

(2009) Dominici F, Fried L, Zeger SL. So Few Women Leaders: Look for the Root Causes. Academe, July-August 2009.

(2012) Wang C, Parmigiani G, Dominici F. Bayesian effect estimation accounting for adjustment uncertainty. Biometrics, (68)3:681-689.

(2014) Zigler CM, Dominici F. Uncertainty in propensity score estimation: Bayesian methods for variable selection and model averaged causal effects. Journal of the American Statistical Association, 109(505):95-107.

(2014) Dominici F, Greenstone M, Sunstein CR. Science and Regulation. Particulate matter matters. Science, 344(6181):257-9.

(2014) Bobb F, Obermeyer Z, Wang Y, Dominici F. Cause-specific risk of hospital admission related to extreme heat in older adults. Journal of the American Medical Association, 312(24):2659-2667. (Recognized in January 2016 as one out of 28 NIEHS Papers of the Year).

 

Awards and prizes

Francesca Dominici has always shown commitment to promoting diversity within the academic sphere. She co-chaired the Women's Condition Commission at John Hopkins University. In 2009 she received the Diversity Recognition Award from the Rector of John Hopkins University. In 2015 she was awarded the Florence Nightingale David Award for her contributions as a model for women and for excellence demonstrated in statistical research, in leadership of multidisciplinary groups and in education. She currently chairs the University Committee for the Advancement of Women at the University of Harvard T.H. Chan School of Public Health.

 

Maria Benedetta Donati
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STEM area: Clinical sciences and nutrition science

Competences: ematology, physiopathology, thrombosis

Keywords: blood, cancer, coagulation, eating habits, food, mediterranean diet, moles-healthy project, nutrition, telethon, thrombosis, tumor

Region: Molise


Position/Role

Head of the Laboratory of Translation and Medicine and of the Neuromed Biobanking Center, Department of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia.

Professional career

MD Degree with the Highest distinction (1968, Catholic University, Rome) specialisation in Clinical and Laboratory Haemotology (1971 same University), Ph.D. in Haemostasis Physiopathology (1973, University of Leuven, Belgium), Honoris Causa Medical Degree from two foreign Universities (Byalistok, Poland and Debrecen, Hungary), Special Mention “For Women in Science” (UNESCO-L’Oreal, Paris 2002), “100 Women Scientists “ (Fondazione Bracco, Milano 2016); “Top Italian Women Scientists”, ONDA, Milano 2016.

 

She has devoted her scientific research to the investigation of thrombosis, the process which leads to the obstruction of blood vessels and may cause major disorders such as myocardial infarction and stroke;  in particular during the first part of her scientific activity at Mario Negri Institute in Milan and subsequently in Consorzio Mario Negri Sud in the Abruzzo Region, she  has pioneered studies on cancer and thrombosis and on the treatment of some tumor types with anticoagulant drugs; in 1993 she launched the First International Group devoted to “Haemostasis and Malignancy” (within the International Society for Haemostasis and Thrombosis). More recently she studied the interaction between genetic and environmental factors as determinants of Cardiovascular Risk, and discovered, together with Licia Iacoviello, the presence of a genetic variant of a clotting factor which protects 20% of the italian population from myocardial infarction.

 

Since 2005 she is one of  the founders and coordinators of the Moli-sani study, an  epidemiological prospective project on nearly 25,000 adults  living in the Molise Region, which evaluates the beneficial effects of the Mediterranean Diet on cardiovascular health and quality of life.

Editorial work and publications

Cultured human endothelial cells generate tissue factor in response to endotoxin.

Colucci M, Balconi G, Lorenzet R, Pietra A, Locati D, Donati MB, Semeraro N.

J Clin Invest1983 Jun;71(6):1893-6. PMID:6345590

 

Polymorphisms in the coagulation factor VII gene and the risk of myocardial infarction.

Iacoviello L1Di Castelnuovo ADe Knijff PD'Orazio AAmore CArboretti RKluft CBenedetta Donati M.

N Engl J Med. 1998 Jan 8;338(2):79-85. doi: 10.1056/NEJM199801083380202

 

Thrombotic complications in childhood acute lymphoblastic leukemia: a meta-analysis of 17 prospective studies comprising 1752 pediatric patients.

Caruso V, Iacoviello L, Di Castelnuovo A, Storti S, Mariani G, de Gaetano G, DonatiMB.

Blood2006 Oct 1;108(7):2216-22. Epub 2006 Jun 27. PMID:16804111

 

Circulating Tissue Factor Levels and Risk of Stroke: Findings From the EPICOR Study.

Iacoviello L1Di Castelnuovo A2de Curtis A2Agnoli C2Frasca G2Mattiello A2Matullo G2Ricceri F2Sacerdote C2Grioni S2Tumino R2Napoleone E2Lorenzet R2de Gaetano G2Panico S2DonatiMB2.

Stroke. 2015 Jun;46(6):1501-7. doi:10.1161/STROKEAHA.115.008678. Epub 2015 Apr 30

 

Interaction between Mediterranean diet and statins on mortality risk in patients with cardiovascular disease: Findings from the Moli-sani Study.

Bonaccio M1Di Castelnuovo A2Costanzo S2Persichillo M2De Curtis A2Cerletti C2DonatiMB2de Gaetano G2Iacoviello L3Moli-sani Study Investigators.

Int J Cardiol. 2019 Feb 1;276:248-254. doi: 10.1016/j.ijcard.2018.11.117. Epub 2018 Nov 24

 

 

 

 

Eleonora Dondossola
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STEM area: Biomedical sciences and biotechnology

Competences: cellular biology, intravital microscopy

Keywords: bones, cancer, molecular therapy, prostate, tissue engineering, tumor metastases

Region: ABROAD


Position/Role

Junior Faculty at MD Anderson Cancer Center, Houston, TX

Professional career

Dondossola got her BSc in Medical and Pharmaceutical Biotechnology and her MSc in Molecular and Cellular Biotechnology at Vita-Salute San Raffaele University, where she further pursued her international PhD studies in Cell and Molecular Biology, in collaboration with the British Open University, followed by a post-doc in Molecular Oncology. She has been teaching Biochemistry and History of Cancer Research at Vita-Salute San Raffaele University since 2008. In 2011 Dondossola moved to UT MD Anderson Cancer Center in Houston, TX, USA, where she is currently working. 

Dondossola joined the American Association for Cancer Research in 2009.

Scientific results

Dondossola’s research activity focuses on the study of the tumor microenvironment, the non-malignant component that supports tumor function and progression. Her initial studies explored the role of tumor blood vessels in metastasis development and therapeutic response. She demonstrated that Chromogranin A, a circulating protein, decreases vascular permeability and inhibits the penetration of therapeutic agents, including chemotherapy and molecular drugs. She further showed that this mechanism reduces the ability of cancer cells to generate metastasis to distant organs and to the tumor itself, a process identified as tumor-self seeding (the property of circulating cancer cells to re-infiltrate their tumor of origin). Dondossola tested the provocative hypothesis that circulating tumor cells can be genetically manipulated and used as anti-cancer treatment thanks to their capacity to spontaneously home to tumors (through the self-seeding process). As a result, the application of engineered tumor cells significantly reduces the growth of both primary and metastatic tumors. Furthermore, she identified a novel population of immune cells (myeloid) that express CD13 protein and support the formation of neo-angiogenic vessels and tumor progression. 

Dondossola recently developed an interest in tissue engineering and intravital multiphoton microscopy, an approach that allows monitoring the dynamic evolution of biological processes over time. These strategies have been combined and applied to understand the mechanisms that support the progression of prostate cancer bone metastasis. She further extended these applications to the study of another non-tumor desmoplastic process, defined foreign body response.

Editorial work and publications

Eleonora Dondossola is an author/coauthor in several important scientific papers, including:

 

[2018]Dondossola E,AlexanderS, HolzapfelBM, FilippiniS, StarbuckMW, HoffmanRM, NavoneN, De-Juan-PardoEM, LogothetisCJ, HutmacherDW, Friedl P. Intravital microscopy of osteolytic progression and therapy response of cancer lesions in bone. Sci Transl Med.2018 Aug 1;10(452)

[2016] Dondossola E, Holzapfel BM, Alexander S, Filippini S, Hutmacher DW, Friedl P. Dissecting the foreign body response to biomaterials by non-linear intravital microscopy. Nat Biomed Eng. 2016 Dec 19; 1, 0007

[2016] Dondossola E, Dobroff AJ, Marchiò S, Cardó-Vila M, Hosoya H, Libutti SK, Corti A, Sidman RL, Arap W, Pasqualini R. Self-targeting of TNF-releasing cancer cells in preclinical models of primary and metastatic tumors. Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2223-8.

 [2013] Dondossola E, Rangel R, Guzman-Rojas L, Barbu EM, Hosoya H, St John LS, Molldrem JJ, Corti A, Sidman RL, Arap W, Pasqualini R.CD13-positive bone marrow-derived myeloid cells promote angiogenesis, tumor growth, and metastasis.Proc Natl Acad Sci USA. 2013 Dec 17;110(51):20717-22.

 [2012] Dondossola E, Crippa L, Colombo B, Elisabetta Ferrero and Corti A. Chromogranin A regulates tumor self-seeding and dissemination. Cancer Research, 2012 Jan 15;72(2):449-59

Awards and prizes

In 2014 she received the AMGEN Award in Basic Science Research from UT MD Anderson Cancer Center, Houston. In the same year she received the Cancer Prevention and Research Institute of Texas Individual Investigator Award. In 2015 she was awarded the Gerald B. Grindey Memorial Scholar-in-Training Award at the AACR Annual Meeting, Philadelphia, USA. In 2016 she got the Mark Walter, Brent Nicklas, Adrianne and Jerry Cohen–PCF Young Investigator Award from the Prostate Cancer Foundation. In 2017 she received the Rolanette and Berdon Lawrence Bone Research Award, The Rolanette and Berdon Lawrence Bone Disease Program of Texas, USA.

Barbara Ensoli
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STEM area: Biomedical sciences and biotechnology

Competences: clinical research, immunology

Keywords: AIDS, aids vaccine, cancer therapy, hiv, hiv vaccine, immunology

Region: Lazio


Position/Role

Director of the National HIV/AIDS Research Center - Istituto Superiore di Sanità, Rome, Italy

Professional career

Barbara Ensoli, M.D., Ph.D., graduated in Medicine and Surgery and specialized in Clinical Immunology and Allergy at the University of Rome “La Sapienza”, Italy. She then spent more than 10 years at the National Institute of Health (Bethesda, Maryland, USA), working at the National Cancer Institute. During those years she elucidated the role of the HIV-1 Tat protein in HIV pathogenesis and AIDS-associated tumors.

Her current research interests are HIV pathogenesis and the development of HIV/AIDS preventative and therapeutic vaccines, which are currently in advanced clinical phase. She has coordinated several international and national research programs in Europe and Developing countries. Among them, the EU-funded "AIDS Vaccine Integrated Project" (AVIP) and the “Program to support the Ministry of Health of South Africa in the implementation of a national program of global response to HIV & AIDS” (Italian Ministry of Foreign Affairs). She is a member of the WHO-UNAIDS Vaccine Advisory Committee and the European Molecular Biology Organisation (EMBO). She has been the Vice-President of the National AIDS Committee of the Italian Ministry of Health from 2006 to 2015 and is a Member of the Editorial Board of the Health Status Report, Ministry of Health. She has been member of Member of the Scientific Council of The European Research Council, ERC from 2013 to 2016 and Member of the HIRO (Heads of International Research Organizations) representing ERC from 2015 to 2016.

She has received many national and international scientific awards and she has been appointed as Ufficiale dell’Ordine al Merito della Repubblica Italiana in 2001 by the President of the Italian Republic Mr. A. Ciampi. Her scientific activities have resulted in more than 300 publications in peer-reviewed journals.

Scientific results

Dr. Ensoli has been involved into two main fields of research:

a)      Studies on the pathogenesis of HIV infection, aimed at developing a vaccine against HIV/AIDS, able to either protect from the disease (in HIV-uninfected individuals; preventative vaccine), or to control disease progression (in HIV-infected individuals; therapeutic immunisation);

b)      Studies on pathogenesis of AIDS-associated tumours, in particular of Kaposi’s sarcoma  and of intra-epithelial neoplasm of uterine cervix and cervical carcinoma.

 

Studies for the development of a vaccine able to prevent from HIV/AIDS disease in uninfected individuals and/or to control disease progression in seropositive patients have been based on new concepts of vaccinology that have lead to identify the Tat protein of HIV-1 as the target for immunisation strategies. This protein has, in fact, a key role in the very early phases of HIV infection since it is essential for virus replication and spreading of infection.

The significant results obtained from the basic research and, later on, the preclinical studies on non-human primates, have confirmed that the Tat-based vaccine is safe, induces humoral and cell-mediated immune responses and is able to block or significantly reduce HIV replication and transmission in vaccinated monkeys. Based on these results, phase I clinical vaccine trials with a vaccine based on the Tat protein on uninfected (ISS P-001) and on HIV-infected volunteers (ISS T-001) have begun in 2003 and completed in 2006. These studies have involved 4 clinical Italian centres and have demonstrated that the Tat vaccine candidate is safe when used in both HIV-negative and –positive individuals. Results from these studies have been published in international scientific journals.

Based on the promising results obtained in phase I clinical trials, a phase 2 clinical trial was started in 2008 in 11 Clinical Centers in Italy with the aim of evaluating immunogenicity induced by vaccination with Tat protein in HIV-positive, HAART-treated, individuals. The study has produced important results of efficacy for the therapeutic immunisation with the Tat protein, also published in international scientific journals.  

 

In parallel with these activities, a bilateral cooperation programme between Italy and South Africa has been conducted, aimed at developing local health programmes to fight HIV/AIDS. The programme has started with preliminary clinical observational studies, then followed by an advanced clinical vaccine trial sponsored by the National HIV/AIDS Research Center of the Istituto Superiore di Sanità in collaboration with the Italian Ministry of Foreign Affairs and the South African Government. The results have been confirmed the data of the phase II trial in Italy and have also been published in scientific international Journals.

Beside the advanced clinical testing of the Tat-based vaccine, second generation vaccines have been developed, in the frame of European research Programmes (An European Programme for the development of a vaccine against HIV/AIDS; AVIP). In particular, a new vaccine candidate, based on the association of the Tat protein with a modified form of the Env protein (an Env protein deleted of its V2 region, ΔV2-Env) has been developed in the frame of the European AVIP programme and of a collaboration with Novartis Vaccines&Diagnostics (one of the most important industries producing vaccines), that is able to elicit a broader immune response. This vaccine candidate , that has produced very promising results in non human primates, has been tested in a phase I clinical trial on healthy volunteers with behaviours at high risk of HIV infection (preventative vaccination).

 

Dr. Ensoli’s research in the field of tumours has lead to the discovery that HIV protease inhibitors (HIV-PI) have anti-tumour effects. Studies started from observation that incidence of HIV-associated tumours, including Kaposi’s sarcoma (KS), non-Hodkin lymphoma and the intra-epithelial neoplasm of uterine cervix (CIN) went reducing since the introduction of new combined anti-retroviral therapies (HAART), containing protease inhibitors. Results from these researchs have demonstrated that PI are molecules with strong anti-angiogenic effects, able to block the development of new blood vessels that are essential to tumour growth in numerous experimental neoplastic models, including KS and CIN, thus suggesting a possible use of these drugs in the anti-tumour  therapy, for both HIV infected patients and patients with HIV unrelated tumours.

Based on these results, two phase II clinical trials has been conducted in Italy in order to evaluate anti-tumour effects of Indinavir, one of the most common HIV-PIs, in HIV-uninfected patients with classic KS. Results from these studies have confirmed that the drug is able to control the progression of the tumour, in particular if given in the early stages of the disease. Due to these promising results, a “proof-of-concept” clinical study has been conducted, aimed at evaluating the efficacy of this class of drugs in the therapeutic treatment of patients with advanced, HIV unrelated, KS in association with conventional chemotherapy.   

The development and the conduct of these programmes in both the oncologic and infectious diseases fields, is an important example of “translational” research, from basic research to clinical advanced testing that assures that a product rapidly reaches the community.

 

 

 

Editorial work and publications

She sits on the editorial boards of Lancet Oncology, PLoS ONE, The Open AIDS Journals, Tumor Viruses, Vaccine, Development and Therapy, Journal of Clinical & Cellular Immunology, Advances in Tumor Virology, Scientific Report.

She has published more than 300 papers in international peer-reviewed journals. Among them:

 

(2016) Ensoli B, Nchabeleng M, Ensoli F, Tripiciano A, Bellino S, Picconi O, Sgadari C, Longo O, Tavoschi L, Joffe D, Cafaro A, Francavilla V, Moretti S, Pavone Cossut MR, Collacchi B, Arancio A, Paniccia G, Casabianca A, Magnani M, Buttò S, Levendal E, Ndimande JV, Asia B, Pillay Y, Garaci E, Monini P. HIV-Tat immunization induces cross-clade neutralizing antibodies and CD4+ T-cell increases in antiretroviral-treated South African volunteers: a randomized phase II clinical trial. Retrovirology, 13(1):34.

(2015) Ensoli F, Cafaro A, Casabianca A, Tripiciano A, Bellino S, Longo O, Francavilla V, Picconi O, Sgadari C, Moretti S, Pavone Cossut MR, Arancio A, Orlandi C, Sernicola L, Maggiorella MT, Paniccia G, Mussini C, Lazzarin A, Sighinolfi L, Palamara G, Gori A, Angarano G, Di Pietro M, Galli M, Mercurio VS, Castelli F, Di Perri G, Monini P, Magnani M, Garaci E, Ensoli B. HIV-1 Tat immunization restores immune homeostasis and attacks the HAART-resistant blood HIV DNA: results of a randomized phase II exploratory clinical trial. Retrovirology, 12:33.

(2012) Monini P, Cafaro A, Srivastava IK, Moretti S, Sharma VA, Andreini C, Chiozzini C, Ferrantelli F, Cossut MR, Tripiciano A, Nappi F, Longo O, Bellino S, Picconi O Fanales-Belasio E, Borsetti A, Toschi E, Schiavoni I, Bacigalupo I, Kan E, Sernicola L, Maggiorella MT, Montin K, Porcu M, Leone P, Leone P, Collacchi B, Palladino C, Ridolfi B, Falchi M, Macchia I, Ulmer JB, Buttò S, Sgadari C, Magnani M, Federico MP, Titti F, Banci L, Dallocchio F, Rappuoli R, Ensoli F, Barnett SW, Garaci E, Ensoli B. HIV-1 Tat promotes integrin-mediated HIV transmission to dendritic cells by binding Env spikes and competes neutralization by anti-HIV antibodies. PLoS One, 7:e48781.

(2003) Sgadari C, Monini P, Barillari G, and Ensoli B. Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth. The Lancet Oncology, 4:537-547.

(2002) Sgadari C, Barillari G, Toschi E, Carlei D, Bacigalupo I, Baccarini S, Palladino C, Leone P, Bugarini R, Malavasi L, Cafaro A, Falchi M, Valdembri D, Rezza G, Bussolino F, Monini P & Ensoli B. HIV protease inhibitors are potent anti-angiogenic molecules and promote regression of Kaposi’s sarcoma. Nature Medicine, 8:225-232.

(1999) Cafaro A, Caputo A, Fracasso C, Maggiorella MT, Goletti D, Baroncelli S, Pace M, Sernicola L, Koanga-Mogtomo ML, Betti M, Borsetti A, Belli R, Åkerblom L, Corrias F, Buttò S, Heeney J, Verani P, Titti F & Ensoli B. Control of SHIV89.6P-infection of cynomolgus monkeys by HIV-1 Tat protein vaccine. Nature Medicine, 5:643-650.

(1994) Ensoli B, Gendelman R, Markham P, Fiorelli V, Colombini S, Raffeld M, Cafaro A, Chang HK, Brady JN & Gallo RC. Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma. Nature, 371:674-680.

(1990) Ensoli B, Barillari G, Salahuddin SZ, Gallo RC & Wong-Staal F. Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients. Nature, 344:84-86.

(1989) Ensoli B, Nakamura S, Salahuddin SZ, Biberfeld P, Larsson L, Beaver B, Wong-Staal F & Gallo RC. AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects. Science, 243:223-226.

(1989) Ensoli B, Lusso P, Schachter F, Josephs SF, Rappaport J, Negro F, Gallo RC & Wong-Staal F. Human herpes virus-6 increases HIV-1 expression in co-infected T cells via nuclear factors binding to the HIV-1 enhancer. EMBO J. 8:3019-3027.

Awards and prizes

She has received many national and international scientific awards. Among them: “San Valentino d’Oro” International Award for  professional activity against AIDS, “Marisa Bellisario” International Award for professional activities, “Domenico Marotta”  Award for year 2000, conferred for professional merits by the National Academy of Sciences (also known as “National Academy of XL”), “Santa Caterina” Award for year 2002, “Paul Harris Fellow” International Award, conferred by the Rotary Foundation “Eminent Scientist of the year 2005 (International Research Promotion Council – World Scientist Forum International Award Science and Medicine), Melvin Jones (Lion’s Club), “The Abraham White Distinguished Science Award” (The George Washington University School of Medicine and Health Sciences - USA and University of Rome Tor Vergata), “Top Italian Women Scientist 2016” award conferred  by Onda, “AcademiaNet-Expert Database for Oustansing Female Scientists and Scholars” (EMBO). She has been appointed as Ufficiale dell’Ordine al Merito della Repubblica Italiana in 2001 by the President of the Italian Republic Mr. A. Ciampi

Elisabetta Erba
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STEM area: Natural and environmental sciences

Competences: geology

Keywords: biosphere, climate, earth, environment, geosphere, nanofossils, oceans, paleontology, soil

Region: Lombardy


Position/Role

Full Professor in Paleontology e Paleoecology at the University of Milano

Professional career

After a diploma (cum laude) in Geological Sciences in 1982, she finished a PhD in Earth Sciences in 1987. In 1987-1988 she was a post-DOC at the Geologisches Institut -.ETH, Zurich. In1990 E. Erba becomes Researcher and in 2000 Associate Professor at the University of Milan. Since 2005 she is Full Professor at the Dept. of Earth Sciences

Scientific results

Elisabetta Erba is specialist of calcareous nanofossils, the most efficient calcite producers in spite of their very small size. When they die, they fall on the sea floor and over the course of millions of years form marine sediments. Nannofossils are used for dating through biostratigraphy and for paleo-oceanographic reconstructions. Elisabetta Erba studies the interactions between geosphere, atmosphere, hydrosphere and biosphere and, in particular, major climate changes. Her research focused on the relationships between atmospheric CO2, climate and ocean ecosystems. In order to understand causes and consequences of current and future climate change it is important to introduce a geological perspective via high-resolution investigations of marine sediments.

Calcareous nannofossils  are also used by Elisabetta Erba to study the nature and origin of organic matter-rich sediments accumulated in stagnant waters, that are potential source rocks to produce oil.

 

Editorial work and publications

E.Erba has published  some 160 papers, including: 


(2018) Gambacorta G., Malinverno A. and Erba E,Orbital forcing of carbonate versus siliceous productivity in the late Albian–early Turonian (Umbria-Marche Basin, central Italy).Newsletters on Stratigraphy, Published online October 2018, DOI: 10.1127/nos/2018/0456

(2018) Bottini C. & Erba E., Mid-Cretaceous paleoenvironmental changes in the western Tethys. Climate of the Past, 14,1147–1163.

(2017) Faucher, G., Hoffmann, L., Bach, L. T., Bottini, C., Erba, E., and Riebesell, U., Impact of trace metal concentrations on coccolithophore growth and morphology: laboratory simulations of Cretaceous stress.Biogeosciences , 14: 3603-3613doi.org/10.5194/bg-14-3603-2017.
(2015) Erba E, Duncan RA, Bottini C, Tiraboschi D. Weissert H, Jenkyns HC, Malinverno A. Environmental Consequences of Ontong Java Plateau and Kerguelen Plateau Volcanism. Geological Society of America, Special Paper 511:271-303. 
(2010) Erba E, Bottini C, Weissert HJ, Keller CE. Calcareous Nannoplankton Response to Surface Water Acidification Around Oceanic Anoxic Event 1a. Science, 329:428-432.   (2006) Erba E. The first 150 million years history of calcareous nannoplankton: biosphere-geosphere interactions. Palaeogeography Palaeoclimatology Palaeoecology, 232:237-250. 
(2005) Muttoni G, Erba E, Kent DV & Bachtadse V. Mesozoic alpine facies deposition as a result of past latitudinal plate motion. Nature, 434:59-63. 
(2004) Erba E. Calcareous nannofossils and Mesozoic Oceanic Anoxic Events. Marine Micropaleontology, 52:85-106.   (2004) Erba, E, Bartolini A, Larson RL. The Valanginian "Weissert Oceanic Anoxic Event. Geology, 32:149-152.   (2004) Erba E & Tremolada F. Nannofossil carbonate fluxes during the Early Cretaceous: phytoplankton response to nutrification episodes, atmospheric CO2 and anoxia. Paleoceanography, 19. 
(2004) Weissert H & Erba E. Volcanism, CO2 and paleoclimate: a Late Jurassic-Early Cretaceous carbon and oxygen isotope record. Journal of the Geological Society of London, 161:695-702.   (1999) Larson RL & Erba E. Onset of the mid-Cretaceous greenhouse in the Barremian-Aptian: Igneous events and the biological, sedimentary and geochemical responses. Paleoceanography, 14:663-678.   (1994) Erba E. Nannofossils and superplumes: the Early Aptian nannoconid crisis. Paleoceanography, 9:483-501.

Awards and prizes

Elisabetta Erba was President of the Italian Geological Society in 2015-2017. Since 2013 she is a Member of theAccademia dei Lincei and of the Academia Europaea (section Earth and Cosmic Sciences). In 2012 she was awarded with the Tartufari Prize for Geosciences  (Accademia Nazionale dei Lincei).

 

Susanna Esposito
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STEM area: Clinical sciences and nutrition science

Competences: allergology, infectious diseases, pediatrics, pneumology

Keywords: antibiotics, infectious diseases, pediatric diseases, pediatrics, vaccines

Region: Umbria


Position/Role

President of the World Association for Infectious Diseases and Immunological Disorders (WAidid), Professor of Pediatrics, Director of the Specialty School for Pediatrics and Director of the S.C. Pediatric Clinic at the University of Perugia

 

Professional career

After graduating in Medicine and Surgery at the University of Milan in 1995, she continued her education with a specialization in Pediatrics (1999) and a next one in Infectious Diseases (2006). Two years after graduating, she was already responsible for the research laboratory of the Pediatric Clinic IV, and since 2000 for the research laboratory of the Clinical Pediatric Clinical Unit of the University of Milan, later called the High Intensity Care Unit of Pediatrics. Susanna Esposito combined her academic career with a medical career: in 2002 she is a university researcher in General and Specialized Pediatrics and since 2005 an associate professor. She also carried out research in foreign institutions: in 2007 in Dallas, Texas, at the Southwestern Medical Center of the University Hospital and Clinic, in 2009 in London, at St George's Medical Center and the following year in Burundi, Africa, at the Kiremba Hospital. From the 2009-2010 academic year, she was Professor of Pediatric Infectious Disease at the Pediatric Infectious Diseases Diploma of the University of Oxford, UK. From 2010 to 2016, she was director of the High Intensity Care Pediatric Unit at the IRCCS Ca 'Granda Foundation, Ospedale Maggiore Policlinico of the University of Milan and head of the Regional Reference Center, in Lombardy, for HIV infection and for pediatric Lyme disease. She is currently Professor of Pediatrics, Director of the School of Specialization in Pediatrics and Director of the S.C. Pediatric Clinic at the University of Perugia. She is president of the World Association for Infectious Diseases and Immunological Disorders (WAidid).

 

Scientific results

Susanna Esposito's scientific activity began during her university studies with research on pediatric infectious diseases, in particular influenza and respiratory viruses, invasive bacteria infections, tuberculosis and HIV. Her field of interest extends progressively to immunology with studies on vaccination, immune response and immunogenetics, pneumology, allergy, rheumatology and rare diseases. She coordinated several research and clinical trials on the role of viruses and bacteria in the main infections in pediatric age and studies on vaccination efficacy, tolerability and safety. She also coordinated the development of guidelines on the diagnostic-therapeutic approach to the main infectious diseases in children and the guidelines on the new vaccination calendar and on the recommended vaccinations for children. In 2012 she identified enterovirus C-117 and enterovirus C-118, two new enteroviruses, a genus of viruses resistant to chemical and physical offenses, which can survive in the environment for a long time, affecting mainly people with low immune defenses, like children and the elderly, with effects in some cases very serious. Since 2013 she has been coordinating the study group on vaccines (EVASG) of the European Society for Clinical Microbiology and Infectious Diseases.

Editorial work and publications

Since 2005 she is a member of the International Board of The Pediatric Infectious Disease Journal, since 2009 she is Associate Editor of BMC Infectious Diseases, since 2011 she is Associate Editor of Human Vaccines & Immunotherapeutics, since 2013 she is Associate Editor of Journal of Clinical Virology and she is part of Editorial Board Member of PLOS One, since 2014 she is Associate Editor of Medicine and since 2016 she is a member of the Editorial Board Member of AIMS Microbiology and of Npj Vaccines. Since 2016 she has also been editor of the magazine Edit Symposia and referee for numerous scientific journals such as Lancet, the British Medical Journal, Vaccine, the European Journal of Clinical Microbiology and Infectious Diseases and the American Journal of Physicians.

Susanna Esposito is the author of more than 1000 publications, including over 450 articles on international journals published on PubMed, and more than 1000 reports on invitation to conferences of national and international scientific societies, including:

 

(2016) Esposito S, Bonanni P, Maggi S, Tan L, Ansaldi F, Lopalco PL, Dagan R, Michel JP, van Damme P, Gaillat J, Prymula R, Vesikari T, Mussini C, Frank U, Osterhaus A, Celentano LP, Rossi M, Guercio V, Gavazzi G. Recommended immunization schedules for adults: Clinical practice guidelines by the Escmid Vaccine Study Group (EVASG), European Geriatric Medicine Society (EUGMS) and the World Association for Infectious Diseases and Immunological Disorders (WAidid). Human Vaccine Immunotherapeutics, 12:1777-1794.

(2016) Esposito S, Principi N. European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Vaccine Study Group (EVASG). Strategies to develop vaccines of pediatric interest. Expert Review of Vaccines, Epub Sep 28.

(2016) Esposito S, Guez S, Orenti A, Tadini G, Scuvera G, Corti L, Scala A, Biganzoli E, Berti E, Principi N. Autoimmunity and cytokine imbalance in inherited epidermolysis bullosa. International Journal of Molecular Science, 17(10):1625.

(2016) Esposito S, Longo MR. Guillain-Barré syndrome. Autoimmunity Review, 16(1):96-101.

(2016) Principi N, Esposito S. Gut microbiota and central nervous system development. Journal of Infection, 73(6):536-546.

(2016) Esposito S, Pietro GD. Respiratory syncytial virus vaccines: an update on those in the immediate pipeline. Future Microbiology, 11:1479-1490.

(2016) Esposito S, Di Gangi M, Cardinale F, Baraldi E, Corsini I, Da Dalt L, Tovo PA, Correra A, Villani A, Sacco O, Tenero L, Dones P, Gambino M, Zampiero A, Principi N, Ita-CAP Study Group. Sensitivity and specificity of soluble triggering receptor Expressed on Myeloid Cells-1, Midregional Proatrial Natriuretic Peptide and Midregional Proadrenomedullin for Distinguishing Etiology and to Assess Severity in Community-Acquired Pneumonia. PLoS One, 11:e0163262.

(2015) Esposito S, Piralla A, Zampiero A, Bianchini S, Di Pietro G, Scala A, Pinzani R, Fossali E, Baldanti F, Principi N. Characteristics and their clinical relevance of respiratory syncytial virus types and genotypes circulating in Northern Italy in five consecutive winter seasons. PLoS One, 10:e0129369.

(2015) Esposito S, Giavoli C, Trombetta C, Bianchini S, Montinaro V, Spada A, Montomoli E, Principi N. Immunogenicity, safety and tolerability of inactivated trivalent influenza vaccine in overweight and obese children. Vaccine, Epub Nov 19.

(2014) Esposito S, Corona F, Barzon L, Cuoco F, Squarzon L, Marcati G, Torcoletti M, Gambino M, Palù G, Principi N. Immunogenicity, safety and tolerability of a bivalent human papillomavirus vaccine in adolescents with juvenile idiopathic arthritis. Expert Review of Vaccines, 13:1387-1393.

Awards and prizes

Susanna Esposito received the "Carlo Imperato" Award in 2002, as part of the 58th National Congress of the Italian Society of Pediatrics, for the best experimental work on "Respiratory diseases of the child", in the same year she was awarded the Young Investigator Award within the III World Congress of Pediatric Infectious Diseases (Santiago, Chile). In 2004 she received the Amici di Milano Award - Gold Medals awarded with the Silver Plate by the President of the Italian Republic and the Silver Plate of the President of the Lombardy Region, as the best medical researcher. In 2008 she was awarded the SIP Member Award as best researcher in general and specialist Pediatrics within the Italian Society of Pediatrics, in 2011 the Ambassador Prize for research abroad in the medical field and in 2014 the Certificate of Merit for the commitment and professionalism over the years dedicated to the health of children by the Amici del Policlinico and Mangiagalli Association. From 2011 to 2014 she was called to chair the Italian Society of Pediatric Infectious Disease (SITIP); from 2012 to 2015 she was president of the Commission of the World Health Organization for the eradication of measles and congenital rubella and continued to participate in the work of the Commission as Past President. Since 2015 she is president of the World Association for Infectious Diseases and Immunological Disorders (WAidid).

 

 

 

 

 

 

 

 

Maria Cristina Facchini
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STEM area: Natural and environmental sciences

Competences: atmospheric science

Keywords: aerosol, atmosphere, climate, clouds

Region: Emilia-Romagna


Position/Role

Research director of the Institute of Atmospheric Sciences and Climate of the CNR, Bologna section

Professional career

Graduated in 1985 at the University of Bologna with a thesis in analytical chemistry, she obtained a PhD at the Department of Chemistry of the same university, and in the same department she became a post doc fellow. In 1987 she was a reaserch fellow at the Institute of Atmospheric Physics of the CNR in Bologna, and held this position until 1992, when she became head of the laboratory of the Regional Agency for Environmental Protection. In 1996 she entered the Institute of Physics and Chemistry of the Low and High Atmosphere of the CNR of Bologna. From 2001 to 2006 she was Senior Scientist at the Institute of Atmospheric and Oceanic Sciences of the CNR. Since 2007 she has been research director of the Institute of Atmospheric Sciences and Climate of the CNR, Bologna section.

 

Scientific results

Maria Cristina Facchini's main research interests are the physical and chemical processes in the atmospheric system such as aerosols and clouds and their effects on changes in atmospheric composition and climate. At the beginning of her scientific career she investigated the chemical properties of fog and clouds, so much so that her first important scientific result regards the organic partition of the aerosol between mist drops and interstitial air. Based on her research, she contributed to the development of a new aerosol investigation technique based on the principles of nuclear magnetic resonance. In 2001 she contributed to a joint paper on Science, where the world's leading experts in the field discussed the need to re-establish the theory of cloud formation on the basis of new discoveries concerning the solubility of aerosols and their surface tension, as well as the effects of soluble gases. Her most recent research concerns the interaction between climate and biota (in ecology, the whole of all living beings, animals and plants, which populate a given region) marine, atmospheric, aerosol.

 

 

 

Editorial work and publications

She is the author of over 150 scientific publications, including:

 

(2011) Decesari S, Finessi E, Rinaldi M, Paglione M, […] Facchini MC. Primary and secondary marine organic aerosols over the north atlantic ocean during the map experiment. Journal of Geophysical Research Atmospheres, 116(D22).

(2011) Rinaldi M, Decesari S, Carbone C, […] Facchini MC. Evidence of a natural marine source of oxalic acid and a possible link to glyoxal. Journal of Geophysical Research Atmospheres, 116(D16).

(2008) Facchini MC, Decesari S, Rinaldi M, et al. An important source of marine secondary organic aerosol from biogenic amines. Environmental Science & Technology, 42:9116-9121.

(2008) Facchini MC, Rinaldi M, Decesari S, et al. Primary submicron marine aerosol dominated by insoluble organic colloids and aggregates. Geophysical Research Letters, 35, L17814.

(2005) Kanakidou M, Seinfeld JH, Pandis SN, Barnes I, Dentener FJ, Facchini MC, et al. Organic aerosol and global climate modelling: a review. Atmospheric Chemistry and Physics, 5:1053-1123.

(2004) O’Dowd CD, Facchini MC, et al. Biogenicallydriven organic contribution to marine aerosol. Nature, 431:676-680.

(2001) Charlson RJ, Seinfeld JH, Nenes A, Kulmala M, Laaksonen M, Facchini MC. Reshaping theory of cloud formation. Science, 292:2025-2026.

(2000) Decesari S, Facchini MC, Fuzzi S & Tagliavini E. Characterization of water soluble organic compounds in atmospheric aerosol: a new approach. Journal of Geophysical Research, 105:1481-1489.

(1999) Facchini MC, Fuzzi S, Zappoli S, et al. Partitioning of the organic aerosol component between fog droplets and interstitial air. Journal of Geophysical Research, 104, 26821-26832.

(1999) Facchini MC, Mircea M, Fuzzi S & Charlson RJ. Cloud albedo enhancement by surface-active organic solutes in growing droplets. Nature, 401:257-259.

 

Awards and prizes

In 2014 she was a Thomson Reuters Highly Cited Researchers Rank, ranking of the most influential researchers and researchers in the world. In the same year she received the Haagen-Smit Prize Award. She is a member of several scientific societies, such as the European Association for Geochemistry, the European Geophysical Union, the American Aerosol Society and is one of the founders of the Italian Aerosol Association.

 

Caterina Falleni
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STEM area: Engineering

Competences: design, technological innovation

Keywords: breathalyser, design, dna, floome, freeijiis, innovation, intelligent systems, inventions, new technologies, no profit, refrigerator without electricity, robot, social innovation

Region: ABROAD


Position/Role

Design Strategist at Awake, San Francisco.

 

Professional career

She graduated in Product & Communication Design at the ISIA of Florence, where she later obtained a Master's degree in Product Design. In 2010 she spent three months in the WAACS Design & Consultancy in Rotterdam, working on various projects, from modeling to the development of innovative products.The following year she became Designer & Consultant for Cristina Fedi Interior Design in Africa, dealing with interior design for the Zalu Resort. In 2012 she won the Axelera Singularity Contest for the creation of Freeijis, a refrigeration system that does not require electricity and thanks to this award she moved to Singularity University, in the Nasa Ames research center in California. The following year she worked as executive director for the same Axelera, a non-profit association created by former students of Singularity University and by young professionals settled in Milan. The aim is to spread the understanding of technologies and to foster the development of Italian potential through collaboration, learning and practical application. Still in Milan, she collaborated with Design Group Italia and, in 2014, she became Product & Experience Design Manager of Makr Shark in Turin, where she took care of the design of the robotic bar, now installed all over the world. Since 2015 Caterina Falleni has been working as Design Strategist for Awake, a digital design agency in San Francisco.

 

Scientific results

For her numerous inventions she has been compared to Joy Mangano, the New Yorker who has patented the Miracle Mop self-wringing rotating broom. The Freeijis project, or zero emission fridge, was born in 2010 following a period of work in Africa, where Caterina Falleni studied some structures made with porous materials such as mud or terracotta. Structures that use the process called evaporative cooling, a refrigeration principle used in Africa and India, and recently applied in the West in the construction sector. A natural example of evaporative cooling is skin sweating which allows the lowering of internal body temperature. This process has been associated with materials called PCM (Phase Change Materials), microcapsules inserted in the water contained in the interspace of the refrigerator, which transform the thermal energy into kinetic energy and trigger a partial evaporation of the liquid. The internal aluminum part, aimed at preserving food, gives up energy in the form of heat to restore the balance of the system, activating the self-cooling of the core in which the food is contained. Among the other inventions that Caterina Falleni is working on, there are Floome, a breathalyzer for smartphones, and X&Y Genomics, a platform to display human DNA, so that everyone can access their genetic information.

 

 

Awards and prizes

In 2012 she received the Axelera Singularity Contest for the creation of Freeijis and, in the same year, she obtained the first place in the "What’s up Young Talents" under the High Patronage of the President of the Republic. In 2014 she won first place at the Wired Hack EXPO in Milan for Floome, a blood alcohol meter that can be interfaced with smartphones. In 2015 she obtained the "CoolIdea" award at the San Francisco SolidCon.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Roberta Fantoni
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STEM area: Physics

Competences: atomic spectroscopy, molecular spectroscopy

Keywords: laser diagnostics, laser induced processes, laser remote sensing

Region: Lazio


Position/Role

Head, Technology Application for Security and Heath Division (FSN-TECFIS) at ENEA since July 2015.

 

Professional career

Degree in Chemistry at Roma University “La Sapienza” in 1978 discussing a thesis on electron spectroscopy in the gas phase. After a period of fellowships, permanent position at ENEA in 1982 initially addressed to the participation to laser assisted uranium isotope enrichment project. At the end of the project she spent some periods of specialization abroad (Catholic University of Nijmegen - NL, ETH Ecole Polytechnique Zurich - CH). Due to her professional expertise on laser diagnostics and photochemistry,  in 1998 she became the head of the Molecular Spectroscopy Laboratory of ENEA at Frascati (FIS-SPET), keeping the charge until  2010. In 2010 she was appointed as director of the large Technical Unit “Applications of radiations” (UTAPRAD) of ENEA at Frascati. Following the last structural changes in ENEA, since 2015 to now, she became head of  Technology Application for Security and Heath Division (FSN-TECFIS) of ENEA at Frascati.

Scientific results

Scientific  activity. From the beginning of her career Dr. R. Fantoni was involved in multidisciplinary research activities and projects implying knowledge relevant to both chemistry and physics (spectroscopy and material processing). Successively, within the field of radiation-matter interactions, she carried out researches on processes with a broader applicative range,  from biology and medicine to cultural heritage. Her well consolidated scientific and technological background was time to time utilized and reshaped for  specific tasks, such as: laser applications in physical chemistry, starting from researches relevant to the laser isotope enrichment project  basically dealing with multi-photon and high resolution IR spectroscopy; laser spectroscopies and diagnostics, including infrared diode laser spectroscopy, laser Raman spectroscopy, emission spectroscopy in visible7ultriaviolet range, multiphoton-ionization spectrometry, Laser Induced  Fluorescence (LIF), Laser Induced Breakdown Spectroscopy (LIBS), Coherent AntiStokes Raman Scattering (CARS), Degenerate Four Wave Mixing (DFWM) e Laser Induced Grating Spectroscopy (LIGS); different multidisciplinary laser application relevant to microelectronics  (thin film deposition), to material science (nano-structures synthesis), to the environment (laser decomposition of liquid and gaseous pollutants) and in situ and remote characterization of cultural heritage surfaces; Organization and participation to monitoring campaigns on sea waters and cultural heritage surfaces.

Along her career Dr R. Fantoni personally established and kept contacts with scientist in European laboratory of excellence (in the Netherlands, Suisse, Romania, Slovenia and Spain) and in other countries (Russia, Egypt).

 

 

Editorial work and publications

She is the co-author of about 165 peer reviewed scientific publications, we report only 5 significant recent titles:

 (2013)  R. Fantoni, S. Almaviva, L. Caneve, F.. Colao, A. M. Popov, G. Maddaluno “Development of Calibration-Free Laser-Induced-Breakdown-Spectroscopy based techniques for deposited layers diagnostics on ITER-like tiles” Spectrochim. Acta B87, 153-160.

(2013 )L. Caneve, F. Colao, R. Fantoni, L. Fiorani "Scanning lidar fluorosensor for remote diagnostic of surfaces" Nuclear Instruments and Methods in Physics Research A 720, 164–167.      

(2014)   S. Almaviva, S. Botti, L. Cantarini,R. Fantoni, S. Lecci, A. Palucci, A. Puiu and A. Rufoloni "Ultrasensitive RDX detection with commercial SERS substrates” J. Raman Spectrosc, 45, 41–46.

(2014) V. Spizzichino, R. Fantoni “Laser Induced Breakdown Spectroscopy in Archeometry: a review of its application and future perspectives” Spectrochim. Acta B 99, 201-209.

(2018) V. Lazic, M. Vadrucci, R. Fantoni, M. Chiari, A. Mazzinghi, A. Gorghinian, Applications of laser induced breakdown spectroscopy for cultural heritage: A comparison with XRF and PIXE techniques, Spectrochim. Acta Part B 149, 1–14.

 

 

Awards and prizes

Co-winner (together with R. Barbini, F. Colao, A. Palucci, S. Ribezzo) of the Prize “Carnia Alpe Verde” for the best project aimed at protection of green areas in 1992, issued by region Friuli Venezia-Giulia.

Winner of the prize “G. Stampacchia” fort he best first work in chemistry in 1980, issued by University of Rome “La Sapienza”.

 

Ilaria Ferlenghi
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STEM area: Biomedical sciences and biotechnology

Competences: microbiology, structural biology, virology

Keywords: EMBL, iNext, meningococcus, structural biology, vaccines

Region: Tuscany


Professional career

After graduating in Biophysics at the University of Tor Vergata in 1993, she continued her studies through a specialization in Plant Biology at the C.R.I.B.I. (Interdepartmental Research Center for Innovative Sciences), at the University of Padua. She then began her research activities for her doctorate at the EMBL laboratories. In 1998 she obtained a PhD in Structural Biology at Ruprecht-Karls-Universitat in Heidelberg, Germany. During her studies she spent several periods of training abroad: in 1996 she performed a stage of 6 months in the Department of Virology of the Medical University of Vienna, in 1998 she did part of her PostDoctoral Fellow at the Howard Hughes Medical Institute, Children's Hospital, Howard Medical School in Boston, MA, USA. In 1999 she was PostDoctoral fellow in the Department of Structural Virology at the C.N.R.S. of Gif-sur-Yvette, France. At the same time (from 2000 to 2003) she collaborated with the Department of Molecular Genetics at the Ecole Normale Superiore in Paris, France. Her training then continued in Italy in 2004 at the GSK Vaccines Research Center (formerly Novartis, in Siena, Italy) firstly as a researcher, then as a Senior Research Investigator and finally in 2009 as Head of Structural Vaccinology. 

Scientific results

Her scientific interests are currently focused on the correlation between bacterial and viral surface protein structures and their functionality. She contributed to the development of the "Structural Vaccinology", a new approach that allows, starting from the knowledg of the three-dimensional structure of the surface proteins, to determine the most effective epitopes of a protein and to engineer them in order to make them more immunogenic and to use them as vaccines. This approach has been instrumental in the development of Bexsero ™, a recently approved FDA vaccine to protect against Meningococcus B infection. The same approach is currently in use in the identification of new vaccine candidates against additional human viral and bacterial pathogens. Since recent years she bacome member of the board of European Networks dedicated to the structural biology (iNext).

Editorial work and publications

Her scientific interests are currently focused on the correlation between bacterial and viral surface protein structures and their functionality. She contributed to the development of the "Structural Vaccinology", a new approach that allows, starting from the knowledg of the three-dimensional structure of the surface proteins, to determine the most effective epitopes of a protein and to engineer them in order to make them more immunogenic and to use them as vaccines. This approach has been instrumental in the development of Bexsero ™, a recently approved FDA vaccine to protect against Meningococcus B infection. The same approach is currently in use in the identification of new vaccine candidates against additional human viral and bacterial pathogens. Since recent years she bacome member of the board of European Networks dedicated to the structural biology (iNext).

Paola Fermo
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STEM area: Chemistry

Competences: analytical chemistry, environmental chemistry

Keywords: air pollution, cultural heritage, emissions, environment, pollution, water

Region: Lombardy


Position/Role

ASSOCIATIONS

Member of SCI (Divisione di Chimica Analitica e Divisione di Chimica dell’Ambiente e dei Beni Culturali)

AIAR (Italian Association of Archaeometry), ACE (Association of Chemistry and the Environment)

Secretary of the SCI Interdivisional Group of Aerosol Science and Technologies  (2009-2012)

Member of consortium INSTM (consorzio internazionale per la scienza e la tecnologia dei materiali)

Member of CRC (centro di ricerca coordinato) Beni Culturali, University of Milan (http://www.crc-beniculturali.unimi.it)

 

SCIENTIFIC COMMITTEES

Member of the scientific committee of the Workshop “Sustainable knowledge and preservation of Cultural Heritage for future generations”; 2-4/05/2016, E-MRS (Materials Research Society) Spring Meeting, Lille (France)

 

Organizer of the section entitled: Measurements for ceramics and glasses

International congress: Metrology for Archaeology, 19-21/10/2016, Torino

 

Member of the scientific committee of YOCOCU congress (Youth in Conservation of Cultural Heritage), Matera, 23-25/05/2018

 

Member of the scientific committee of SIMA (Società Italiana di Medicina Ambientale) (http://www.simaonlus.it)

Professional career

1993    Degree in Chemistry, University of Milan (110/110)

1997    PhD in Chemistry, University of Milan

1997– 1999 Technical collaborator in the Department of Inorganic, Metallorganic and   Analytical Chemistry,  University of Milan

1999 – 2014 Researcher in Analytical Chemistry, Department of Inorganic, Metallorganic and  Analytical Chemistry, University of Milan

since 2015 - Associate Professor of Analytical Chemistry, Department of Chemistry, University of Milan

National Scientific qualification (ASN) as PO:  sector 03/A1 – SSD CHIM01 (call 2016-2018, primo quadrimestre)

Scientific results

Atmospheric and environmental chemistry:

Characterization of aerosol particulate matter (PM) carried out by different analytical techniques for the quantification and speciation of main species (carbonaceous fraction and ions); analysis of specific markers for the identification of aerosol PM sources.

Effect of environmental pollution on cultural heritage: study of black crust present on historical monuments in polluted environments; indoor air quality assessment  in museums and art galleries.

Chemical characterization of biomarkers of environmental pollution (honey or plant leaves); food analysis and food safety control.

 

Analytical chemistry applied to cultural heritage:

provenance and technological study of archaeological and Renaissance ceramics, paintings, mortars, etc.; new coatings based on nano-materials for the protection of materials of artistic-historical-interest (marbles, mortars).

 

Editorial work and publications

110 scientific publications on international peer-review journals (Scopus and Web of Science) in the field of environmental and analytical chemistry as well as archaeometry; 20 conference proceeding; 16 book chapters; more than 200 communications in national and international congresses; invited speakers in national and international congresses.

h-index=28

More then Citations= 2384

applicate ai settori ambientale, beni culturali e alimentare”, 21/06/2005, Milan

 

TEACHING ACTIVITY

Adjoint Professor 2001-2013;

since 2015 Associate Professor of Analytical Chemistry (CHIM01).  Scince 1999 teaching activity for undergraduate and graduate courses leading to Bachelor of Science (BS) and Master of Science (MS) degrees in Chemistry and Industrial Chemistry

Member of the board of professors of PhD in Chemistry, University of Milan; supervisor of students (more than 60 Master’s theses in Chemistry; supervisor of 4 PhD students)

Teaching activity for PhD: 2003-2016

 

Recent Publications (2017-2018)

 

(2019) Ielpo, P., Mangia, C., Marra, G.P., Comite, V., Rizza, U., Uricchio, V.F., Fermo, P.

Outdoor spatial distribution and indoor levels of NO2 and SO2 in a high environmental risk site of the South Italy

Science of the Total Environment, 648, pp. 787-797.

 

(2018) Paola Fermo, Sara Goidanich, Valeria Comite, Lucia Toniolo, Davide Gulotta, Study and characterization of environmental deposition on marble and surrogate substrates at a monumental heritage site;Geosciences; in press

(2018) Maria Letizia Amadori, Valentina Raspugli, Valeria Comite, Paola Fermo, Francesco Maria Mini, Mauro La Russa, Yoshifumi Maekawa,

Integrated Scientific Investigations On Constitutive Materials From Me-taw-ya Temple, Pagán Valley, Burma (Myanmar),Measurement,ISSN 0263-2241,https://doi.org/10.1016/j.measurement.2018.09.004; in press

 

(2018) Amadori, M.L., Pallante, P., Fermo, P., Emami, M.A., Chaverdi, A.A., Callieri, P., Matin, E.

Advances in Achaemenid brick manufacturing technology: Evidence from the monumental gate at Tol-e Ajori (Fars, Iran)

Applied Clay Science, 152, pp. 131-142.

 

(2018) Vecchi, R., Bernardoni, V., Valentini, S., Piazzalunga, A., Fermo, P., Valli, G.

Assessment of light extinction at a European polluted urban area during wintertime: Impact of PM1 composition and sources

Environmental Pollution, 233, pp. 679-689.

 

(2018) Daellenbach, K.R., El-Haddad, I., Karvonen, L., Vlachou, A., Corbin, J.C., Slowik, J.G., Heringa, M.F., Bruns, E.A., Luedin, S.M., Jaffrezo, J.-L., Szidat, S., Piazzalunga, A., Gonzalez, R., Fermo, P., Pflueger, V., Vogel, G., Baltensperger, U., Prévôt, A.S.H.

Insights into organic-Aerosol sources via a novel laser-desorption/ionization mass spectrometry technique applied to one year of PM10 samples from nine sites in central Europe

Atmospheric Chemistry and Physics, 18 (3), pp. 2155-2174.

 

(2017) Bernardoni, V., Elser, M., Valli, G., Valentini, S., Bigi, A., Fermo, P., Piazzalunga, A., Vecchi, R.

Size-segregated aerosol in a hot-spot pollution urban area: Chemical composition and three-way source apportionment

Environmental Pollution, 231, pp. 601-611. Cited 1 time.

 

(2017) Daellenbach, K.R., Stefenelli, G., Bozzetti, C., Vlachou, A., Fermo, P., Gonzalez, R., Piazzalunga, A., Colombi, C., Canonaco, F., Hueglin, C., Kasper-Giebl, A., Jaffrezo, J.-L., Bianchi, F., Slowik, J.G., Baltensperger, U., El-Haddad, I., Prévôt, A.S.H.

Long-term chemical analysis and organic aerosol source apportionment at nine sites in central Europe: Source identification and uncertainty assessment

Atmospheric Chemistry and Physics, 17 (21), pp. 13265-13282.

 

(2017) La Russa, M.F., Fermo, P., Comite, V., Belfiore, C.M., Barca, D., Cerioni, A., De Santis, M., Barbagallo, L.F., Ricca, M., Ruffolo, S.A.

The Oceanus statue of the Fontana di Trevi (Rome): The analysis of black crust as a tool to investigate the urban air pollution and its impact on the stone degradation

Science of the Total Environment, 593-594, pp. 297-309.

 

(2017) Marabini, L., Ozgen, S., Turacchi, S., Aminti, S., Arnaboldi , F., Lonati , G., Fermo , P., Corbella , L., Valli , G., Bernardoni , V., Dell'Acqua , M., Vecchi , R., Becagli , S., Caruso, D., Corrado , L.G., Marinovich , M.

Ultrafine particles (UFPs) from domestic wood stoves: genotoxicity in human lung carcinoma A549 cells

Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 820, pp. 39-46.

 

(2017) Bozzetti, C., El Haddad, I., Salameh, D., Daellenbach, K.R., Fermo, P., Gonzalez, R., Minguillón, M.C., Iinuma, Y., Poulain, L., Elser, M., Müller, E., Slowik, J.G., Jaffrezo, J.-L., Baltensperger, U., Marchand, N., Prévôt, A.S.H.

Organic aerosol source apportionment by offline-AMS over a full year in Marseille

Atmospheric Chemistry and Physics, 17 (13), pp. 8247-8268.

 

(2017) Amadori, M.L., Del Vais, C., Fermo, P., Pallante, P.

Archaeometric researches on the provenance of Mediterranean Archaic Phoenician and Punic pottery

Environmental Science and Pollution Research, 24 (16), pp. 13921-13949.

 

(2017) Corsini, E., Vecchi, R., Marabini, L., Fermo, P., Becagli, S., Bernardoni, V., Caruso, D., Corbella, L., Dell'Acqua, M., Galli, C.L., Lonati, G., Ozgen, S., Papale, A., Signorini, S., Tardivo, R., Valli, G., Marinovich, M.

The chemical composition of ultrafine particles and associated biological effects at an alpine town impacted by wood burning

Science of the Total Environment, 587-588, pp. 223-231.

 

(2017) Pino, F., Fermo, P., La Russa, M., Ruffolo, S., Comite, V., Baghdachi, J., Pecchioni, E., Fratini, F., Cappelletti, G.

Advanced mortar coatings for cultural heritage protection. Durability towards prolonged UV and outdoor exposure

Environmental Science and Pollution Research, 24 (14), pp. 12608-12617.

 

(2017) Bigi, A., Bianchi, F., De Gennaro, G., Di Gilio, A., Fermo, P., Ghermandi, G., Prévôt, A.S.H., Urbani, M., Valli, G., Vecchi, R., Piazzalunga, A.

Hourly composition of gas and particle phase pollutants at a central urban background site in Milan, Italy

Atmospheric Research, 186, pp. 83-94.

 

(2017) Ozgen, S., Becagli, S., Bernardoni, V., Caserini, S., Caruso, D., Corbella, L., Dell'Acqua, M., Fermo, P., Gonzalez, R., Lonati, G., Signorini, S., Tardivo, R., Tosi, E., Valli, G., Vecchi, R., Marinovich, M.

Analysis of the chemical composition of ultrafine particles from two domestic solid biomass fired room heaters under simulated real-world use

Atmospheric Environment, 150, pp. 87-97. Cited 7 times.

 

(2017) Benetello, F., Squizzato, S., Hofer, A., Masiol, M., Khan, M.B., Piazzalunga, A., Fermo, P., Formenton, G.M., Rampazzo, G., Pavoni, B.

Estimation of local and external contributions of biomass burning to PM2.5 in an industrial zone included in a large urban settlement

Environmental Science and Pollution Research, 24 (2), pp. 2100-2115. 

(2017) Chiara Pietrogrande, M., Barbaro, E., Bove, M.C., Clauser, G., Colombi, C., Corbella, L., Cuccia, E., Dalla Torre, S., Decesari, S., Fermo, P., Gambaro, A., Gianelle, V., Ielpo, P., Larcher, R., Lazzeri, P., Massabò, D., Melchionna, G., Nardin, T., Paglione, M., Perrino, C., Prati, P., Visentin, M., Zanca, N., Zangrando, R.

Results of an interlaboratory comparison of analytical methods for quantification of anhydrosugars and biosugars in atmospheric aerosol

Chemosphere, 184, pp. 269-277. 

(2017) Corsini E, Ozgen S, Papale A, Galbiati V, Lonati G, Fermo P, Corbella L, Valli G, Bernardoni V, Dell'Acqua M, Becagli S, Caruso D, Vecchi R, Galli CL, Marinovich M. Insights on wood combustion generated proinflammatory ultrafine particles (UFP). Toxicology Letters, 266, 74-84.

Antonella Ferrara
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STEM area: Engineering

Competences: advanced automatic control, control engineering, robotics

Keywords: autonomous driving, control of microgrids and power networks, human-robot interaction, process control, robotics, smart mobility, vehicle control, vehicle traffic control

Region: Lombardy


Position/Role

Full Professor of Automatic Control at University of Pavia

Professional career

She got her M.Sc. in Electronic Engineering in 1987 and her PhD in Electronic and Computer Engineering in 1992. She became Assistant Professor at the University of Genova (April 1992), Associate Professor at the University of Pavia (November 1998) and Full Professor of Automatic Control always at the University of Pavia (January 2005).

Scientific results

She has been dealing with the control of complex systems (robotic systems, vehicle networks, vehicular traffic, power networks also based on renewable energy resources). She proposed new algorithms for the control of plants and processes the mathematical model of which is affected by uncertainties. She proposed new approaches to control vehicle traffic in transportation networks with the aim of reducing congestion and environmental impact. She has been working in advanced vehicle control, collaborating with major car manufacturers and coordinating the Italian research group in two European projects (PROTECTOR, ITEAM). In particular, she proposed solutions for driving assistance systems (ADAS) and autonomous driving. She has been studying human-robot interaction proposing an approach based on the joint use of conventional control methodologies and artificial intelligence (deep reinforcement learning). She published more than 380 scientific works, including 118 articles in international journals and 3 scientific books. She also contributed with chapters to 23 edited books.

Editorial work and publications

[2019]Ferrara A, Incremona G.P, Cucuzzella M. Advanced andOptimization Based Sliding Mode Control. SIAM.

 

[2018]Ferrara A, Simona S, Siri S. Freeway Traffic Modelling and Control. Springer.

 

[2017]Ferrara A, (Ed.).Sliding Mode Control of Vehicle Dynamics. IET Digital Library.

 

[2019] Regolin E, Alatorre A, Zambelli M, Victorino A, Charara A, Ferrara A. A Sliding Mode Virtual Sensor for Wheel Forces Estimation with Accuracy Enhancement via EKF. IEEE Transactions on Vehicular Technology, 68(4): 3457-3471.

 

[2018]  Sangiovanni B, Rendiniello A, Incremona G.P, Ferrara A, Piastra M. Deep Reinforcement Learning for Collision Avoidance of Robotic Manipulators, Proceedings of the European Control Conference ECC 2018, Limassol, Cyprus.

 

[2018]Canudas de Wit C., Ferrara A. A Variable-Length Cell Transmission Model for Road Traffic Systems. Transportation Research Part C: Emerging Technologies, 97: 428-455.

 

[2018]Cucuzzella M, Lazzari R, Trip S, Rosti S, Sandroni C, Ferrara A. Sliding mode voltage control of boost converters in DC microgrids, Control Engineering Practice, 73:161-170.

 

[2017]Cucuzzella M, IncremonaG.P, Ferrara A. Decentralized Sliding Mode Control of Islanded AC Microgrids with Arbitrary Topology. IEEE Transactions on Industrial Electronics, 64(8): 6706-6713.

 

[2017]Incremona G.P, Ferrara A, Magni L. MPC for Robot Manipulators with Integral Sliding Modes Generation. IEEE/ASME Transactions on Mechatronics, 22(3):1299-1307.

 

[2015]Ferrara A, Simona S, Siri S. Event-triggered model predictive schemes for freeway traffic control.Transportation Research Part C: Emerging Technologies, 58(Part C):554–567.

 

[2015]Goggia T, Sorniotti A, De Novellis L, Ferrara A, Gruber P, Theunissen J, Steenbeke D, Knauder B, Zehetner J. Integral Sliding Mode for the Torque-Vectoring Control of Fully Electric Vehicles: Theoretical Design and Experimental Assessment. IEEE Transactions on Vehicular Technology64(5):1701-1715.

 

[2012]Capisani L, Ferrara A, Trajectory Planning and Second Order Sliding Mode Motion/Interaction Control for Robot Manipulators in Unknown Environments.IEEE Transactions on Industrial Electronics, 59(8):3189 – 3198. 

Awards and prizes

IEEE North Italy Section Electrical Engineering Student Award, 1986

Senior Member of theIEEE, 2003

Outstanding Reviewer for Automatica Award, 2006

Chair of the Women in Control Committee of the IEEE Control Systems Society (2013-2016)

Member of the Board of Governors IEEE Control Systems Society (2012; 2016-2018)

Member of the European Control Association (EUCA) Council (Since 2015)

EPSON EMEA WIN-A-ROBOT Contest Award, 2019

 

Elena Ferrari
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STEM area: Computer science

Competences: computer technology

Keywords: big data, data management systems, iot, privacy, safety, social networks, social web

Region: Lombardy


Position/Role

Full professor of Computer Science at the University of Insubria in Varese.

Professional career

After graduating in Computer Science at the University of Milan in 1992, she continued her education with a PhD in Computer Science at the same university in 1998. During the summer of 1996 she carried out a period of research as a Visiting Researcher at the Department of Computer Science at George Mason University in Fairfax, Virginia. In the following two years is a visiting researcher at Rutgers University in Newark, New Jersey. In 1998 he returned to Italy and worked as assistant professor of Computer Science at the University of Milan. Later she became full professor of Computer Science at the University of Insubria in Varese.

Scientific results

Her research activities are linked to various aspects of data management systems, including web security, access control and privacy. Recently she has been involved in several research projects such as "ISocial" which develops advanced systems for the protection of privacy in social networks. She worked on the EU Euphorbia project, which provided for a series of experiments on filtering documents on the Internet according to an impartial approach. The aim was to produce a new, more powerful and flexible information review system, able to adapt to the cultural needs of each user. This system is capable of making a selection based on the semantic content of the information, and adapts to the description of the topics on a given website. She is currently involved in security and privacy issues in the IoT (Internet of Things) and Big Data areas.

Editorial work and publications

She is author of numerous publications, including:

 

(soon to be published) N. Laleh, B. Carminati, E. Ferrari. Risk Assessment in Social Networks based on User Anomalous Behaviour. IEEE Transactions on Dependable and Secure Computing.

(2015) P. Colombo, E. Ferrari. Privacy aware access control for Big Data: a research roadmap. Big Data Research, 2(4).

 

(2014) Akcora C, Carminati B, Ferrari E, Kantarcioglu M. Detecting Anomalies in Social Network Data Consumption. Social Network Analysis Mining, 4(1):231.

 

(2014) Parra-Arnau J, Perego A, Ferrari E, Fornè J & Rebollo-Monedero D. Privacy-Preserving Enhanced Collaborative Tagging. IEEE Transactions on Knowledge and Data Engineering, 26(1):180-193.

 

(2013) Carminati B, Ferrari E, Viviani M. Security and Trust in Online Social Networks, Synthesis Lectures on Information Security, Privacy and Trust. Morgan & Claypool.

(2011) Cao J, Carminati B, Ferrari E, Tan KL. CASTLE: Continuously Anonymizing Data Streams. IEEE Transactions on Dependable and Secure Computing, 8(3): 337-352.

 

(2010) Bonchi F, Ferrari E. Privacy-Aware Knowledge Discovery: Novel Applications and New Techniques. Chapman & Hall/CRC Data Mining and Knowledge Discovery Series.

 

Articles from international conferences:

 

(2016) Carminati B, Colombo P, Ferrari E & Sagirlar G. Enhancing User Control on Personal Data Usage in Internet of Things Ecosystems. Proceedings of the 13th IEEE International Conference on Services Computing, San Francisco, USA.

 

(2016) Colombo P & Ferrari E. Towards Virtual Private NoSQL Datastores. Proceedings of the32nd IEEE International Conference on Data Engineering, Helsinki, Finlandia.

 

(2014) Bahri L, Carminati B, Ferrari E. Community-based Identity Validation on Online Social Networks. Proceedings of the 34th International Conference on Distributed Computing Systems Madrid, Spagna.

 

Awards and prizes

 

In 2009 Elena Ferrari was awarded for her research in the field of privacy and security by one of the two most important international associations of reference (IEEE - Institute of Electrical and Electronic Engineers) with the Technical Achievement Award. In 2011 she obtained the Google Research Award for her work in the field of privacy in social networks, while in 2014 she received the IBM Faculty Award for her investigation on big data privacy. She is IEEE fellow and ACM (Association for Computing Machinery) Distinguished Scientist.

 

Florinda Ferreri
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STEM area: Psychology and neurosciences

Competences: clinical neurophysiology, neurology

Keywords: brain aging, brain plasticity, dementia, neuromodulation, neuroscience

Region: Veneto


Position/Role

Associate Professor of Neurology in the Department of Neuroscience at the University of Padua, Italy.

Professional career

Dr. Florinda Ferreri received honors in Medicine in 2001 and certification in Neurology in 2006 from the University Campus Bio-Medico of Rome-Italy, and PhD in Clinical Neurophysiology in 2012 from the University of Eastern Finland, Kuopio-Finland. In 2006 she was Research Assistant at the Department of Psychiatry, University of Wisconsin-Madison, USA. From 2007 to 2016 Dr. Ferreri was Neurologist Consultant with expertise in Neurophysiology, teaching and research duties at the University Hospital Campus Bio-Medico of Rome and in 2016 she was appointed Assistant Professor. As of April 2018, Dr. Ferreri is Associate Professor of Neurology in the Department of Neuroscience at the University of Padua, Italy.

Scientific results

Dr. Florinda Ferreri research activities focus on the study of the physiology of human motor cortex and its pathophysiology in neurodegenerative disorders by using highly innovative neurophysiological techniques and multimodal data collection. In 2008 Dr. Ferreri worked in an international research group that obtained the first direct control of a biomechatronic prosthetic hand via neural interfaces implanted in the peripheral nerves of an amputated patient. In recent years, Dr Ferreri’s commitment has been focused on the technological transfer towards the early diagnosis of neurological diseases and towards rehabilitation procedures with non-invasive electromagnetic stimulations of the brain.

Editorial work and publications

[2016) Ferreri F, Vecchio F, Vollero L, Guerra A, Petrichella S, Ponzo D, Määtta S, Mervaala E, Könönen M, Ursini F, Pasqualetti P, Iannello G, Rossini PM, Di Lazzaro V. Sensorimotor cortex excitability and connectivity in Alzheimer’s disease: A TMS-EEG Co-registration study. Human Brain Mapping, 37[6):2083-96.

[2015) Rossini PM, Burke D, Chen R, Cohen LG, Daskalakis Z, Di Iorio R, Di Lazzaro V, Ferreri F, Fitzgerald PB, George MS, Hallett M, Lefaucheur JP, Langguth B, Matsumoto H, Miniussi C, Nitsche MA, Pascual-Leone A, Paulus W, Rossi S, Rothwell JC, Siebner HR, Ugawa Y, Walsh V, Ziemann U. Non-invasive electrical and magnetic stimulation of the brain, spinal cord, roots and peripheral nerves: Basic principles and procedures for routine clinical and research application.An updated report from an I.F.C.N. Committee. Clinical Neurophysiology Journal,. Feb 10. Review.

[2014) Di Pino G, Pellegrino G, Assenza G, Capone F, Ferreri F, Formica D, Ranieri F, Tombini M, Ziemann U, Rothwell JC, Di Lazzaro V. Modulation of brain plasticity in stroke: a novel model for neurorehabilitation. Nature Reviews Neurology, 10(10):597-608.

[2006) Ferreri F. Curcio G. Patrizio P. De Gennaro L. Fini R. and Rossini PM. Mobile phone emission and human brain excitability. Annals of Neurology, 60(2):188-96.

[2003) Ferreri F, Pauri F, Pasqualetti P, Fini R, Dal Forno G, PM Rossini. Motor cortex excitability in Alzheimer Disease. Annals of Neurology, 53(1):102-8.

 

Debora Fino
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STEM area: Engineering

Competences: biotechnologies, chemical plants, energy, environment

Keywords: biofuels, carbon dioxide conversion, catalysis, chemical reactors, circular economy, pollutants elimination, waste reduction

Region: Piedmont


Position/Role

Professor of Chemical Plants at the Polytechnic of Turin; Waste, Water and Food Manager of the Politecnico di Torino (Green Team).

Professional career

After graduating in Chemical Engineering at the Polytechnic University of Turin, she continued her studies through a PhD program in Chemical Engineering, where she obtained the title at the same University.

She won a workplace as University Researcher in Chemical Engineering, in the scientific sector for Chemical Plants in November 2002, obtaining confirmation. From July 2010 to March 2016 she worked as Associate Professor in the same SSD. In March 2016 she became full professor of Chemical Plants, where she is currently responsible for a research group consisting of 15 young researchers and PhD students at the Department of Applied Science and Technology of the Politechnic University of Turin. She is a member of the College of Chemical and Materials Engineering a the College of Energy, her teaching activity is focused on the courses of Plants for the Chemical and Food Industry and Re-use Processes and Energy Enhancement.

Scientific results

Her scientific interests focus mainly on the catalytic treatment of Diesel emissions (eg: filtration and combustion of particulates, the removal of nanoparticles, reduction and adsorption of NOx, development of catalytic traps), on the catalytic combustion of methane (eg: development of catalytic converters for methane-fueled cars), on catalytic filters for the treatment of fumes (eg.: multi-functional systems for the removal of fly ash, NOx and dioxins from incinerators) where she obtained several industrial loans (General Motors, Officine Metallurgiche Cornaglia, Petronas, Pirelli, ....), she won national and community projects (PRIN, TOP-Expert, ADDnano, FlameSOFC, ...) and she has 2 patents. Among her environmental research projects, the systems of advanced oxidation of pollutants (eg reactors and electrocatalysts for the electrochemical oxidation of biorefractory organic pollutants, such as phenol, antibiotics and other drugs, dyes, ...; remediation of polluted soil and self-cleaning surfaces) are of particular importance. Among the research undertaken in recent years of particular importance are the results obtained regarding the analysis of waste treatment platforms, the life cycle analysis of industrial processes from a circular economy perspective, where also in the agri-food sector has collaborated with industries of reference in the sector (eg Waste Italia, Ferrero, Ago Renewables, ENI, Lavazza, AUSTEP, etc.) also obtaining important structured financing as in the case of the Innovative Agro-Food-ECOFOOD platform project coordinated by Ferrero, Research & Innovation for The Improvement of the Sustainability of the Agro-Food Chain, of which Debora Fino was responsible for all the research actions of her University. She currently coordinates the research of 2 Horizon 2020 projects funded by the European Community CELBICON (Cost-effective CO2 conversion into chemicals via combination of Capture, Electrochemical and Biochemical Conversion technologies) and BIOROBURPLUS (Advanced direct biogas fuel processor for robust and cost-effective decentralized Hydrogen production ).

 

 

Editorial work and publications

She is author of over 200 scientific publications, including:

 

(2018) Malavè A C L, Fino D, Gómez Camacho C E, Ruggeri B.  Experimental tests on commercial Sweet Product Residue (SPR) as a suitable feed for anaerobic bioenergy (H2+ CH4) production, Waste Management, 71: 626-635.

(2017) Massa A, Hernandez Ribullen S P, Lamberti A, Galletti C, Russo N, Fino D. Electro-oxidation of phenol over electrodeposited MnOx nanostructures and the role of a TiO2 nanotubes interlayer. Applied Catalysis. B, Environmental, 203: 270-281.

(2016) Negro V, Mancini G, Ruggeri B, Fino D. Citrus waste as feedstock for bio-based products recovery: Review on limonene case study and energy valorization. Bioresource Technology, 214: 806-815.

(2015) Hussain M, Deorsola F A, Russo N, Fino D, Pirone R. Abatement of CH4 emitted by CNG vehicles using Pd-SBA-15 and Pd-KIT-6 catalysts, Fuel, 149: 2-7.

(2014) Mancini G, Viotti P, Luciano A, Fino D. On the ASR and ASR thermal residues characterization of full scale treatment plant, Waste Management, 34: 448-457.

(2013) Ruggeri B, Luongo Malavè A C, Bernardi M, Fino D. Energy efficacy used to score organic refuse pretreatment process for hydrogen anaerobic production, Waste Management, 33: 2225-2233.

(2012) Bensaid S, Deorsola F A, Fino D, Russo N. After-treatment of household wood-fired stove emissions: from catalyst formulation to full-scale system, Catalysis Today, 197: 76-89.

(2011) Palmisano P, Hernandez S P, Hussain M, Fino D, Russo N. A new concept for a self cleaning household oven, Chemical Engineering Journal, 176-177: 253-259.

(2010) Bensaid S, Russo N; Fino D. Power and Hydrogen Co-generation from Biogas, Energy & Fuels, 24: 4743-4747.

(2009) Rutigliano L, Fino D, Saracco G, Specchia V, Spinelli P, Grizzaffi L. Electrochemical Oxidation process for water condensates recycling in a shuttle orbiter, Journal Of Applied Electrochemistry, 39 (11): 2239-2249.

(2008) Rutigliano L, Fino D, Saracco G, Specchia V, Spinelli P. Electrokinetic remediation of soils contaminated with heavy metals, Journal Of Applied Electrochemistry, 38: 1035-1041.

(2007) Fino D. Diesel Emission Control:Catalytic Filters for Particulate Removal, Science And Technology Of Advanced Materials, 8 (1-2): 93-100.

(2006) Cauda E, Hernandez S, Fino D, Saracco G, Specchia V. PM0.1 Emissions during Diesel Trap Regeneration, Environmental Science And Technology, 40: 5532-5537.

(2005) Fino D, Carlesi J C, Saracco G, Specchia V, Spinelli P. Deactivation and regeneration of Pt anodes for the electro-oxidation of phenol, Journal Of Applied Electrochemistry, 35(4): 405-411.

(2004) Fino D, Russo N, Saracco G, Specchia V.  A multifunctional filter for the simultaneous removal of fly-ash and NOx from incinerator flue gases, Chemical Engineering Science, 59 (22-23): 5329-5336.

(2003) Fino D, Russo N, Saracco G, Specchia V.  The role of suprafacial oxygen in some perovskites for the catalytic combustion of soot, Journal Of Catalysis, 217: 367-375.

(2002) Fino D, Saracco G, Specchia V. Filtration and catalytic abatement of diesel particulate from stationary sources, Chemical Engineering Science, 57(22-23): 4955-4966.

 

Awards and prizes

In November 2004 she was winner of the "ITALGAS AWARD - DEBUT IN THE RESEARCH" (XVII edition) for her doctoral thesis (Catalytic combustion of Diesel particulate matter). In February 2007 her article "Innovative means for the catalytic regeneration of particulate traps for diesel exhaust cleaning", Chem. Eng. Sci., 58 (3-6) (2003) 951-958, was awarded by Elsevier Science Publisher as one of the most cited articles of the journal Chemical Engineering Science during the four-year period 2003 - 2006. In December 2007 she was winner of the "SAPIO JUNIOR AWARD for ITALIAN RESEARCH" (IX Edition) for the results obtained in the research "Secondary nanoparticles from filters for the removal of Diesel particulate matter and in other application contexts". October 2009 - the article "Biogas Purification for MCFCs Applications" was awarded among the top 5 by the Scientific Organizing Committee of "HYSYDAYS 2009 - 3rd World Congress of Young Scientists on Hydrogen Energy Systems". The article was published in the International Journal of Hydrogen Energy.
June 2010 - ITWIIN Award for Italian Association of Women Inventors and Innovators, she also won of the DISTI (Science and Technology Information Innovation Innovation Center based in Bari) special prize, given the effectiveness of the presentation of potential social and economic impacts of scientific projects.
In September 2011, the European Union Women Inventors and Innovators Awards awarded her a special mention in view of the effectiveness in presenting potential social and economic effects of her scientific research by the jury of international experts, Reykjavik (Iceland). In February 2013 the article "M. Hussain, R. Ceccarelli, D.L. Marchisio, D. Fino, N. Russo, F. Geobaldo, Synthesis, Characterization and Photocatalytic Application of Novel TiO2 Nanoparticles "in Chemical Engineering Journal 157, 45-51 of 2010 was awarded as the eighth most cited article of the journal Chemical Engineering Journal in the during the period 10/2009 - 9/2010.

 

 

 

 

 

 

 

 

 

 

Serena Fonda Umani
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STEM area: Natural and environmental sciences

Competences: marine ecology

Keywords: biodiversity, carbon flows, food chain, marine biology, marine ecosystem, plankton, sea

Region: Friuli-Venezia Giulia


Professional career

Serena FONDA, was born in Trieste on 3.2.1950, she is married with a daughter. She was full Professor of Marine Ecology (University of Trieste) since 2005. Serena Fonda had a B.S. degree in Biology from the University of Trieste in 1973. In 1974 she was granted by a fellowship from the Ministry of Instruction, which lasted until 1981 when she became Researcher. Then in 1992 she became Associate Professor in Ecology at the University of Trieste. She spent several months at the SCRIPPS Institution of Oceanography (University of California, San Diego, USA) in the laboratory of prof. Farooq Azam. She had been visiting scientist at Horn Point Laboratory (University of Maryland, USA) at the College of Fishery (University of Tromso, Norway), at the Department of Zoology of the University of Athens (Greece). She has taken active part in many field researches, also as chief scientist (Mediterranean Sea, Ross Sea (Antarctica), Magellan Straights, Chesapeake Bay). She was the Director of Marine Biology Laboratory (now part of the Department of Oceanography of OGS) from 1992 until 2005. She was the President of the PhD course in Environmental Life Sciences. She acted as supervisor for 40 PhD students and > 200 undergraduate students.

Scientific results

 Her professional interest concerns marine plankton ecology (from virus to mesozooplankton), and more in general marine bio-geo-chemical fluxes. She has been acting as team leader for >20 regional, national and international research projects. PI in the Eurocean net. Member of the editorial board for 4 international scientific journals. Reviewer for >30 scientific journals, several international projects, and ANVUR. External advisor for NIB (Slovenia). One of the promoters of the Italian LTER. President of SItE (Italian Society of Ecology) in 2015 -2016. Member of the administrative board of the “Stazione Zoologica – Anton Dohrn” of Naples.

 

Editorial work and publications

Invited speaker at several international and national meetings. She published >330 scientific papers, >200 in peer-reviewed journals, > 100 ISI for a total of >4600 citations. Her personal H = 36.

Bibliography

1.      ChustG, VillarinoE, ChenuilA, IrigoienX, BizselN, BodeA, BromsC, ClausS, Fernández de Puelles1ML, Fonda-UmaniS, HoarauG, MazzocchiMG, MozetičP, VandepitteL, VeríssimoH, ZervoudakiS, BorjaA (2016) Dispersal similarly shapes both population genetics and community patterns in the marine realm. Scientific Rep. 6 (28730) DOI: 10.1038/srep28730     

2.      ZoccaratoL, CelussiM, PallaviciniA, Fonda UmaniS (2016) Aurelia auritaephyrae reshape a coastal microbial community. Front. Microbiol,7:749 doi: 10.3389/fmicb.2016.00749

3.      Di Poi E, Blason C, Corinaldesi , Danovaro R, Malisana E, Fonda Umani S(2013) Structure and interactions within the pelagic microbial food web (from viruses to microplankton) across environmental gradients in the Mediterranean Sea. Global Biogeoc. Cycles, 27: 1034 – 1045  DOI: 10.1002/2013GB004589

4.      GianiM., DjakovacT., DegobbisD., CozziS., SolidoroC., Fonda UmaniS (2012) Recent changes in the marine ecosystems of the northern Adriatic Sea. Estuar Coast Shelf S, 115: 1 – 13. doi.org/10.1016/j.ecss.2012.08.023

5.      Fonda Umani S, Malfatti F, Del Negro P (2012) Carbon fluxes in the pelagic ecosystem of the Gulf of Trieste (Northern Adriatic Sea). Estuar Coast Shelf S, 115: 170 – 186. doi: 10.1016/j.ecss.2012.04.006empty

Simonetta Gallerini
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STEM area: Chemistry

Competences: industrial chemistry, total quality management

Keywords: business model canvas, Kaizen Monozukuri WG, Lean, risk assessment, Six Sigma, Toyota Way

Region: ABROAD


Position/Role

Quality Assurance in SAGEA Centro di Saggio Srl, International Contract Research Organisation and International Consultant for TQM and Lean Six Sigma projects at COMATCH GmbH Berlin.

Professional career

After the Master Degree in Chemistry (Industrial Chemistry sector) at the University of Florence Industrial Organic Chemistry Dep. (1999) and one fellowship at the ConsorzioC.I.R.M.M.P.Consorzio Interuniversitario per la ricerca sulle Metallo-ProteineUniversity of Florence, she has many working expertise in topics related to the study and improvement of company processes and analytical methods: Pharma at the Eli Lilly Italy Medical Area, Environment at the ARPAT Dep. Waste and Soil Remediation, C.T.A. Srl Environmental Consulting.

From 2000 to 2017 Technical Consultant of the Law Court of Florence.

From 2003 to May 2008, she worked at the ALPHA ECOLOGIA Srl to reach the Accreditation ISO17025 by ACCREDIA, company processes and lab activities continuous improvement.

From 2006 she was a Certified Internal Auditor for the Quality Management System (ISO19011), skills certificated by CSQA. 

From May 2008 to February 2016 she worked in Biochemielab Srl: first as Head Lab Manager, to implement the Quality Management System with process approach, to implement the QA/QC EPA Standard Quality System, continuous improvement of the Accreditation ISO17025 by ACCREDIA, digitization lab activities; afterwards as Lead Quality Assurance Manager working to quality-environment-safety integrated system, ISO9001 and ISO14001 certification, Accreditation ISO17025 by ACCREDIA, continuous improvement of company processes.

Since March 2016, she works in SAGEA Centro di Saggio Srl, an International Contract Research Organisation in Agrifood, as Quality Assurance Manager; dealing with GLP and GEP certification as internal auditor; she has implemented the Quality Management System ISO9001, process approach of Japanese model of Total Quality Management and now she’s working to improve the company processes with the help of Lean Six Sigma methodologies.

Since 2016 she is Italian President of Food sector of AICQ (Associazione Italiana Cultura Qualità) for the Quality diffusion in the Agri-food sector and Italian vice-president of AICQ Calibration and Testing Laboratory Committee for the Quality diffusion in the laboratories.

Since 2019 she is Green Belt Six Sigma and she is an International Consultant for TQM and Lean Six Sigma Projects at the COMATCH GmbH located in Berlin.

Scientific results

Since 2000 expertise in company implementation of Japanese model of Total Quality Management(Toyota Way), continuous improvement Kaizen, company processes analyse and Lean Six Sigma Projects, company organization of MonozukuriWG. 

On 2013 she partecipated as speaker at following Conferences:

  • Quality-Day “Fare qualità oggi nel laboratorio analisi delle acque, Accreditamento delle metodiche test in cuvetta per le analisi delle acque” with title “L’esperienza per la misura del COD”, HACHLANGE-ACCREDIA, Florence
  • Plenaria Congiunta “Idrocarburi in matrici ambientali”, IDRO 2012, with title “ISO 16703:2004 e EPA 8015D 2003 due metodi a confronto per la determinazione del parametro C12-C40”, UNICHIM, Milan
  • “Validazione di un metodo interno per un laboratorio privato”, with title “Metodo interno MP015: determinazione di istamina nel pesce fresco e conservato”, ALA/ACCREDIA/ARPA Marche, Pesaro

 

Since 2016 her AICQ activity allowed to participate at many Conferences with Istituto Superiore di Sanità, ACCREDIA, AICQ-SICEV:

  • 2016-2017 Working Group AICQ/ACCREDIA to revise ISO17025 Standard, Padua 
  • 2017, Speaker and Scientific Responsible “I PRINCIPI DI BUONA PRATICA DI LABORATORIO E LA CERTIFICAZIONE DEI CENTRI DI SAGGIO” in collaboration with Istituto Superiore di Sanità, Bologna
  • 2017, Conference AICQ-ACCREDIA “LA NUOVA NORMA ISO 17025:2017 PER I LABORATORI DI PROVA E DI TARATURA”, Padua
  • 2017 Speaker and Responsible for the Seminar “FSSC22000 v.4.1: REQUISITI E COME SODDISFARLI”, AICQ-CN Milan
  • 2018 creation and validation of the Training Course AICQ-SICEV for Auditor/Lead Auditor Quality Management System (40 hours) AgriFood sector – Bio products, ISO9001, D.Lgs. n.20 23/02/2018
  • 2018, Working Group for the Training Course AICQ-SICEV “Le innovazioni della nuova ISO 19011:2018” (16 hours)
  • Since 2018 she is Member UNI/CT 003 "Agrifood commission” with the right to vote, member UNI/CT003/GL21 "Biostimulants" with the right to vote, member UNI/CT406 “Fertilizers” with the right to vote, member UNI/CT003/GL23 “Food Authenticity” with the right to vote.

Since 2019 she is one of theResponsible of the Training European Project ENVIRECA-ERASMUS+ with partnership of European Commission, AICQ, DU, FLA, HRC, CSM and EXELIA “Cooperation for innovation and the exchange of good practices, Strategic Partnerships for vocational education and training” in the HORECA sector.

Maria Cristina Gambi
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STEM area: Natural and environmental sciences

Competences: marine biology

Keywords: biodiversity, ecology, environmental factors, evolutionary biology, oceans, polychaetes, sea

Region: Campania


Position/Role

Senior investigator at the Stazione Zoologica Anton Dohrn di Napoli.

Professional career

M.C. Gambi got her Master's degree in Biological Sciences at the University of Siena in 1977 with the maximum score. From 1980 to 1982 she was a member of the Cooperative of Marine Biology, Hydrobiology and Aquaculture, "Coipa" (Rome). In 1983 she started her research activity as a scientist staff member of the Stazione Zoologica Anton Dohrn in Naples, at the Benthic Ecology Laboratory, located in Villa Dohrn, Ischia. In 1986 he held a year post-doc Fullbright fellowship at the School of Oceanography of the University of Washington (WA, USA) and at the Friday Harbor Laboratories. Since 1992 she is senior researcher (equivalent to Associate Professor) of the Stazione Zoologica. She leaded the Antarctic benthic ecology programme of the Stazione Zoologica from 1990 to 2006, and she and her collaborators participated in twelve Antarctic expeditions and two sub-Antarctic cruises with Italian, German and Spanish organizations and research ships. From 2015 to 2018 she coordinated the Villa Dohrn-Benthic Ecology Center at Ischia. In 2014 she obtained the national scientific habilitation for Ecology (full professor) and Zoology (associate professor).

Scientific results

The research of Maria Cristina Gambi aims to study the diversity and evolutionary biology and ecology of marine benthic invertebrates with special focus on polychaetes (one of the most abundant and diverse groups of benthic assemblages) and their role as bioindicators and in the functioning of coastal benthic habitats. As part of her main results, Maria Cristina Gambi described 16 species of polychaetes new to science and a new and peculiar group of detritivores (debris consumers) in the seagrass Posidonia oceanica system of the Mediterranean and the Thalassia testudinum system in the Caribbean. She identified key species of polychaetes and other invertebrates resistant to various stress factors related to climate change, in particular to ocean acidification, that can be used as models to study acclimatization and adaptation to local conditions of this stressor and other forcing environmental factors. Actually, experimental research on climate change effects on polychaetes and zoobenthic communities are carried out both in the laboratory and in situ, utilizing submerged systems characterized by of emissions of CO2 of volcanic origin from the bottom (gas vents) which cause a natural acidification of the marine water and represent natural laboratories to study future scenario of climate change and ocean acidification. The studies conducted in these systems by M.C. Gambi pionereed the world international research on the effects of ocean acidification in the benthic biota.  

 

Editorial work and publications

From2005 to 2013 Editor, and from 2014 to present Associate Editor of the International Journal Marine Ecology (Wiley-Blackwell). 

She is author of over 270 scientific publications, including some books, and has edited various special issues of Marine Ecology (Wiley-Blackwell); the most recent and relevant publications are listed below: 

(2018) Teixido N, Gambi MC, Parravicini V, Kroeker K, Micheli F, Villeger S, Ballesteros E. Functional biodiversity loss along natural CO2 gradients. Nature Communications, 9(1). DOI.10.1038/s41467-018-07592-1.

(2018) Foo SA, ByrneM, RicevutoE, Gambi MC. The carbon dioxide vents of Ischia, Italy, a natural laboratory to assess impacts of ocean acidification on marine ecosystems: an overview of research and comparisons with other vent systems. Oceanography and Marine Biology: An Annual Review, 56, 237-310

(2017) Vizzini S, Martínez-Crego B, Andolina C, Massa-Gallucci A, Connell SD, Gambi MC. Ocean acidification as a driver of community simplification via the collapse of higher-order and rise of lower-order consumers. Scientific Report 7, 4018.DOI: http://10.0.4.14/s41598-017-03802-w

(2013) Kroeker K, Micheli F, Gambi MC. Ocean acidification causes ecosystem shifts via altered competitive interactions. Nature Climate Change, 3, 156-159. 
(2013) Kroeker KJ, Gambi MC, Micheli F. Altered recovery dynamics result in homogenous assemblages in an acidified ocean. Proceedings of the National Academy of Sciences, USA (PNAS), 110 (31): 12721-12726. 
(2011) Kroeker KJ, Micheli F, Gambi MC, Martz TR. Divergent ecosystem responses within a benthic marine community to ocean acidification. Proceedings of the National Academy of Sciences USA (PNAS), 108 (35), 14515-14520. 

Awards and prizes

She is member of the Italian Society of Marine Biology (S.I.B.M.) since 1977, where she participated in the Steering Committee of the Society from 2009 to 2012 and was for various times coordinator of the Benthos Committee. She also member of the Italian Zoological Association (U.Z.I.), and the Italian Association of Oceanology and Limnology (A.I.O.L.). She has been also a member of the GOSSOE group (Group of Specialists of Southern Ocean Ecology) of the S.C.A.R.-S.C.O.R.

From 1992 to 2001 she was the national representative of the Steering Committee of the International Polychaete Association (I.P.A.) (1992-2001) and from 2001 to 2004 she has been its President.

Sara Gandini
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STEM area: Clinical sciences and nutrition science

Competences: biostatistics, epidemiology

Keywords: colon cancer, melanoma, meta analysis, vitamin d

Region: Lombardy


Position/Role

Deputy Director of the Division of Epidemiology and Biostatistics of the IEO (European Institute of Oncology) in Milan

Professional career

She graduated in Statistics at the University of Bologna in 1993, continuing her education through a specialization in Biometrics in 1995 at the University of Reading (UK). In 1996 she joined the IEO of Milan, when the Institute had just 2 years of activity behind it; there she constantly carried out research activities. In 2004 she obtained a PhD in Epidemiology at the University of Birmingham (Public Health). Since 2009 she has been Deputy Director of the Biostatistics and Epidemiology Division of the IEO in Milan and in 2014 she became a Statistic consultant for the Multimedica Ethics Committee in Milan.

 

Scientific results

Sara Gandini, within the Division of Epidemiology and Biostatistics of the IEO, provides constant advice in a wide range of sectors, including statistical analysis of experiments and clinical studies, protocol development, interpretation and discussion of results. She collaborates with researchers around the world and has conducted extensive research on cancer epidemiology, including systematic literature reviews and meta-analysis, with the aim of better understanding the aetiology of cancer. In recent years her main interest has focused on the study of melanoma and the related risk factors that led to changing the classification of the International Agency for Cancer Research in Lyon, defining exposure to the full spectrum of ultraviolet as carcinogenic. Sara Gandini has thus come to analyze the role of vitamin D within the complex system of the human body, discovering a consistent association between low presence of vitamin D and propensity to the development of colon cancer. One of the most important results is certainly the meta-analysis study which demonstrates the lowering of the mortality rate due to each cause thanks to vitamin D. She is the scientific Principal Investigator of two randomized studies that she designed and promoted to evaluate the effect of vitamin D on the prognosis of patients with melanoma and colon cancer. In general, she believes in independent research and in her career she has dealt not only with primary prevention and the study of biomarkers, including Drug repositioning, with the re-use in oncology of the active ingredient of commercial drugs (Vitamin D, Metformin, Beta-blockers ...), on which there are no economic interests and investments by pharmaceutical companies.

Editorial work and publications

Sara Gandini is the author of numerous articles in national and international journals, including:

 

(2016) Le CP, Nowell CJ, Kim-Fuchs C, Botteri E, Hiller JG, Ismail H, Pimentel MA, Chai MG, Karnezis T, Rotmensz N, Renne G, Gandini S, et al. Chronic stress in mice remodels lymph vasculature to promote tumour cell dissemination. Nature Communications, 7:10634.

(2014) Gandini S, Puntoni M, Heckman-Stoddard BM, Dunn BK, Ford L, DeCensi A, Szabo E. Metformin and cancer risk and mortality: a systematic review and meta-analysis taking into account biases and confounders. Cancer Prevention Research (Philadelphia), 7(9):867-85.

(2012) Boniol M, Autier P, Boyle P, Gandini S. Cutaneous melanoma attributable to sunbed use: systematic review and meta-analysis. British Medical Journal, 345:e4757.

(2012) Zittermann A, Iodice S, Pilz S, Grant WB, Bagnardi V, Gandini S. Vitamin D deficiency and mortality risk in the general population: a meta-analysis of prospective cohort studies.

The American Journal of Clinical Nutrition, 95(1):91-100.

(2011) Gandini S, Boniol M, Haukka J, et al. Meta-analysis of observational studies of serum 25-hydroxyvitamin D levels and colorectal, breast and prostate cancer and colorectal adenoma. International Journal of Cancer, 128(6):1414-24.

(2010) DeCensi A, Puntoni M, Goodwin P, Cazzaniga M, Gennari A, Bonanni B, Gandini S. Metformin and Cancer Risk in Diabetic Patients: A Systematic Review and Meta-analysis. Cancer Prevention Research (Philadelphia), 3(11):1451-61.

(2007) Autier P, Gandini S. Vitamin D suppl. and total mortality - A meta-analysis of randomized controlled trials. Archives of Internal Medicine, 167(16):1730-7.

(2005) Gandini S, et al. Meta-analysis of risk factors for cutaneous melanoma: II. Sun exposure. European Journal of Cancer, 41(1):45-60.

(2005) Gandini S, et al. Meta-analysis of risk factors for cutaneous melanoma: I. Common and atypical naevi. European Journal of Cancer, 41(1):28-44.

(2005) Gandini S, et al. Meta-analysis of risk factors for cutaneous melanoma: III. Family history, actinic damage and phenotypic factors. European Journal of Cancer, 41(14):2040-59.

 

Awards and prizes

In 2008 she won the Bruno Martinetto award for research on cancer prevention. In 2014 she was unanimously elected President of the independent scientific society EuroSkin that deals with primary prevention.

Cecilia Garlanda
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STEM area: Biomedical sciences and biotechnology

Competences: immunology

Keywords: cancer cure, immunology, immunopathology, infections, inflammation, preclinical studies

Region: Lombardy


Position/Role

Head of the Experimental Immunopathology Laboratory of the Humanitas Clinical Institute in Milan

 

Professional career

After graduating in Veterinary Medicine at the University of Milan in 1990, she specialized in immunopathology working in Italian and foreign laboratories, such as the Immunology Laboratory of the "Mario Negri" Institute of Pharmacological Research from 1990 to 2005, and the Department of Molecular Biology of the Grenoble Nuclear Studies Center for the two-year period 1994-1995. She is currently in charge of the Laboratory of Experimental Immunopathology at the Humanitas Clinical Institute. Her interests concern the cells of the immune system and the characterization of their biological activity, innate immunity to pathogens and regulation of inflammatory processes.

 

Scientific results

The research group in charge of Cecilia Garlanda is focused on the study of the PTX3 molecule, the innate immunity molecule involved in resistance to fungal, bacterial and viral infections, and in the regulation of inflammation. Recently the group pointed out that PTX3 creates an environment hostile to tumor growth, regulating the inflammation that is generated in the tumor microenvironment. Cecilia Garlanda also engages in pre-clinical studies and in studies aimed at the possibility of transferring the information obtained to clinical activity.

 

Editorial work and publications

Author of over 165 scientific publications, including:

 

(2015) Doni A, Musso T, Morone D, Bastone A, Zambelli V, Sironi M, Castagnoli C, Cambieri I, Stravalaci M, Pasqualini F, Laface I, Valentino S, Tartari S, Ponzetta A, Maina V, Barbieri SS, Tremoli E, Catapano AL, Norata GD, Bottazzi B, Garlanda C, Mantovani A. An acidic microenvironment sets the humoral pattern recognition molecule PTX3 in a tissue repair mode. J Exp Med, 1;212(6):905-25.

(2015) Bonavita E, Gentile S, Rubino M, Maina V, Papait R, Kunderfranco P, Greco C, Feruglio F, Molgora M, Laface I, Tartari S, Doni A, Pasqualini F, Barbati E, Basso G, Galdiero MR, Nebuloni M, Roncalli M, Colombo P, Laghi L, Lambris JD, Jaillon S, Garlanda C, Mantovani A. PTX3 is an extrinsic oncosuppressor regulating complement-dependent inflammation in cancer. Cell, 12;160(4):700-14.

(2014) Jaillon S, Moalli F,  Ragnarsdottir B, Bonavita E, Riva F,  Barbati E, Nebuloni M, Cvetko Krajinovic L, Markotic A, Valentino S,  Doni A, Tartari S, Graziani G, Montanelli A, Delneste Y, Svanborg C, Garlanda C,  Mantovani A. The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection. Immunity, 17;40(4):621-32.

(2013) Garlanda C, Dinarello CA, Mantovani A, The interleukin-1 family: back to the future. Immunity, 12;39(6):1003-18.

(2010) Moalli F, Doni A, Deban L, Zelante T, Zagarella S, Bottazzi B, Romani L, Mantovani A, and Garlanda C. Role of complement and Fcg receptors in the protective activity of the long pentraxin PTX3 against Aspergillus fumigatus. Blood, 9;116(24):5170-80.

(2007) Garlanda C, Riva F, Veliz T, Polentarutti N, Pasqualini F, Radaelli E, Sironi M, Nebuloni M, Zorini EO, Scanziani E, Mantovani A. Increased susceptibility to colitis-associated cancer of mice lacking TIR8, an inhibitory member of the interleukin-1 receptor family. Cancer Research, 1;67(13):6017-21.

(2005) Garlanda C, Bottazzi B, Bastone A, Mantovani A. Pentraxins at the crossroads between innate immunity, inflammation, matrix deposition, and female fertility. Annual Review of Immunology, 23: 337-366.

(2004) Garlanda C, Riva F, Polentarutti N, Buracchi C, Sironi M, De Bortoli M, Muzio M, Bergottini R, Scanziani E, Vecchi A, Hirsch A, Mantovani A. Intestinal inflammation in mice deficient in Tir8, an inhibitory member of the IL-1 receptor family. Proceedings of the National Academy of the Sciences of the United States of America, 101: 3522-3526.

(2002) Garlanda C, Hirsch E, Bozza S, Salustri A, De Acetis M, Nota R, Maccagno A, Riva F, Bottazzi B, Peri G, Doni A, Vago L, Botto M, De Santis R, Carminati P, Siracusa G, Altruda F, Vecchi A, Romani L, Mantovani A. Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature, 420: 182-186.

(2000) Hirsch E, Katanaev V L, Garlanda C, Azzolino O, Pirola L, Silengo L, Sozzani S, Mantovani A, Altruda F, Wymann MP. Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation. Science, 287: 1049-1053.

 

Amalia Gastaldelli
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STEM area: Biomedical sciences and biotechnology

Competences: biomedical engineering, physiopathology, translational medicine

Keywords: diabetes, liver, metabolic diseases, metabolism, obesity, pollutant endocrine disruptors, preventive medicine

Region: Tuscany


Position/Role

She is director of the Cardiometabolic Risk Laboratory and Coordinator of human metabolic research at the Clinical Physiology Institute of the CNR of Pisa, she is also Adjunct associate professor at the Division of Diabetes, University of Texas Health at San Antonio, USA.

Professional career

After graduating in 1990 in Electronic Engineering with a specialization in Bioengineering at the University of Padua, she continued her education with a PhD in Bioengineering at the Polytechnic University of Milan and a PhD in Preventive Medicine and Community Health, specialized in Human Physiology , at the University of Texas Medical Branch of Galveston, where she was a fellow from 1991 to 1995. In that period her research focused on the physiological mechanisms that regulate the metabolism of sugars, lipids and proteins using innovative techniques based on the infusion of tracers marked with stable isotopes measured in mass spectrometry, and on their kinetics’ analysis by mathematical models. In 1995 she returned to Italy to found the Stable Isotope Laboratory at the Institute of Clinical Physiology of the CNR, in the Unit of Metabolism and Nutrition of Pisa. From 2008 to 2009 she was Director of the Mass Spectrometry Laboratory of the G. Monasterio Foundation of Pisa and then in 2009 she returned as a researcher to the CNR Clinical Physiology Institute of Pisa to the CNR, where she founded the Cardiometabolic Risk Laboratory and coordinated research metabolic in humans. In addition to research, she has also been involved in the academic career since 2011: she was first Assistant, then Associate Professor at the University of Texas Health Science Center, Diabetes Division, in San Antonio; from 2006 to 2011 she was a contract professor at the Faculty of Engineering (a degree course in Biomedical Engineering) of the University of Pisa.
Since 2010 she has been a member of the board of directors of the American College of Nutrition (ACN) and she has been directing its European Chapter. In 2012 she founded the study group on non-alcoholic hepatic steatosis (NAFLD) of the European Society for the Study of Diabetes (EASD), and since then she has been leading it.

 

Scientific results

Amalia Gastaldelli is a PhD specialized in human physiology, an expert in the study of human metabolism, cardio-metabolic risk and glucose and lipid metabolism pathologies, such as insulin resistance, non-insulin-dependent diabetes and non-alcoholic hepatic steatosis. Her multidisciplinary training allowed her to carry out translational research to study human metabolism. Using tracers marked with stable isotopes and mathematical models she showed that the liver is central to proper metabolic functioning. She was among the first to show how fasting hyperglycemia in diabetic patients is mainly due to excessive hepatic glucose production by gluconeogenesis and how patients with fatty liver (NAFLD) have an altered metabolism not only in the liver, but also in the muscle and adipose tissue. She holds several European grants that study the physiopathological mechanisms of NAFLD. At the same time she was a co-investigator in many clinical trials that studied the mechanism of action of antidiabetic drugs such as: PPAR + receptor agonists (TZD), able to increase insulin sensitivity in various organs and to decrease liver fat; the agonists of the GLP-1 hormone produced by the intestine which act as incretins stimulating the production of insulin; and DPP4 enzyme inhibitors responsible for its degradation. A new line of research investigates the impact of pollutants that act as endocrine disruptors on the health of adults and children.

Editorial work and publications

Amalia Gastaldelli is an Associate Editor and a member of the Commitee for the publication of the Journal of the American College of Nutrition, she is on the Editorial Board of the World Journal of Hepatology and World Journal of Diabetes, and is a reviewer for over twenty international peer review journals. She is the author of over 200 scientific articles and book chapters including:

 

(2016) Gastaldelli A, Gaggini M, Daniele G, Ciociaro D, Cersosimo E, Tripathy D, Triplitt C, Fox P, Musi N, DeFronzo R, Iozzo P. Exenatide improves both hepatic and adipose tissue insulin resistance: A dynamic positron emission tomography study. Hepatology, 64(6), 2028-2037.

 

(2016) EASL, Marchesini G, Day CP, Dufour JF, Canbay A, Nobili V, Ratziu V, Tilg H, EASD, Roden M, Gastaldelli A, Yki-Järvinen H, Schick F, EASO, Vettor R, Frühbeck G, Mathus-Vliegen L. EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease. Journal of Hepatology, 64(6), 1388-1402.

 

(2014) Salehi M, Gastaldelli A, D'Alessio DA. Blockade of glucagon-like peptide 1 receptor corrects postprandial hypoglycemia after gastric bypass. Gastroenterology, 146(3), 669-680 e662.

 

(2013) DeFronzo RA, Tripathy D, Schwenke DC, Banerji M, Bray GA, Buchanan TA, Clement SC, Henry RR, Kitabchi AE, Mudaliar S, Ratner RE, Stentz FB, Musi N, Reaven PD, Gastaldelli A, Study AN. Prediction of diabetes based on baseline metabolic characteristics in individuals at high risk. Diabetes Care 36(11):3607-3612.

(2012) Bradley D, Conte C, Mittendorfer B, Eagon JC, Varela JE, Fabbrini E, Gastaldelli A, Chambers KT, Su X, Okunade A, Patterson BW, Klein S. Gastric bypass and banding equally improve insulin sensitivity and beta cell function. Journal of Clinical Investigation, 122(12), 4667-4674.

 

(2009) Gastaldelli A, Kozakova M, Hojlund K, Flyvbjerg A, Favuzzi A, Mitrakou A, Balkau B, Risc Investigators. Fatty liver is associated with insulin resistance, risk of coronary heart disease, and early atherosclerosis in a large European population. Hepatology, 49(5), 1537-1544.

 

(2007) Gastaldelli A, Cusi K, Pettiti M, Hardies J, Miyazaki Y, Berria R, Buzzigoli E, Sironi AM, Cersosimo E, Ferrannini E, DeFronzo RA. Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects. Gastroenterology, 133(2), 496-506.

 

(2006) Belfort R, Harrison SA, Brown K, Darland C, Finch J, Hardies J, Balas B, Gastaldelli A, Tio F, Pulcini J, Berria R, Ma JZ, Dwivedi S, Havranek R, Fincke C, DeFronzo R, Bannayan GA, Schenker S, Cusi K. A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. The New England Journal of Medicine, 355(22), 2297-2307.

 

(2004) Gastaldelli A, Ferrannini E, Miyazaki Y, Matsuda M, DeFronzo RA, San Antonio Metabolism study. Beta-cell dysfunction and glucose intolerance: results from the San Antonio metabolism (SAM) study. Diabetologia, 47(1), 31-39.  

(2000) Gastaldelli A, Baldi S, Pettiti M, Toschi E, Camastra S, Natali A, Landau BR, Ferrannini E. Influence of obesity and type 2 diabetes on gluconeogenesis and glucose output in humans: a quantitative study. Diabetes, 49(8), 1367-1373.

 

Awards and prizes

During her university career, Amalia Gastaldelli received numerous awards, including over 80 readings by invitation in national and international congresses. In 1998, she was awarded the Glaxo Wellcome / EASD Burden of Diabetes prize for the study of gluconeogenesis and in 2016 she joined the Top Italian Scientist for Biomedical Sciences. She participated in many scientific commissions for the organization of national and international congresses and for the selection of international research projects (grant), and is a member of several international scientific societies.
She is also the scientific director of the European Chapter of the American College of Nutrition (ACN), a professional organization created to promote scientific research in the field of nutritional sciences; she is president of the European study group for non-alcoholic hepatic steatosis NAFLD-EASD and member of the Steering Committee of the EGIR group (European Group for the Study of Insulin Resistance).

 

Simonetta Gentile
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STEM area: Physics

Competences: experimental physics

Keywords: atlas project, CERN, higgs boson, neutrinos, nucleons, particle physics

Region: Lazio


Position/Role

Full Professor of Experimental Physics at the La SapienzaUniversity of Rome

Professional career

After obtaining a degree in Physics at the University La Sapienza of Rome in 1974, she received a training grant at the same University from 1975 to 1981. In 1978 she graduated from the School of Specialization in Physics (Nuclear Physics)(corresponding to a nowadays PhD). From 1980 to 1982 she was a two-year research  fellow at the Division of Experimental Physics of CERN (European Organization for Nuclear Research). In 1981 she worked as researcher at the La SapienzaUniversity of Rome until 1988 when she became an associate professor at the University of Calabria. In 1992  and 1993 and in1999 and 2000 she returned to CERN as Visiting Scientist. In 1992 she moved as associate professor at University La Sapienza. Since 2011 she is  Full Professor of Experimental Physics at La Sapienza in Rome.

Scientific results

The research sector, in which Simonetta Gentile is dedicated, concerns the Experimental Physics of Elementary Particles. Her lines of investigation follow the Standard Model (the theory that describes three of the four known fundamental forces: the strong, electromagnetic and weak interactions, and all the elementary particles connected to them) or the Neutrino Physics, the structure functions of the nucleons, the properties of the intermediate bosons Z and W and the search for the Higgs bosons. It is currently part of the ATLAS project (A Toroidal LHC ApparatuS), one of six particle detectors built for the Large Hadron Collider (LHC), the particle accelerator at CERN, in Switzerland. Simonetta Gentile is also involved in research and development for particle detectors for future accelerators. During her career, she participates in experiments aimed at identifying triggers and detectors of mu-mesons (muons, sort of heavy electrons). She collaborated with the Fermi Laboratory of Batavia (Chicago) in the search for particles with charm and with NASA working  at AMS, the Alpha Magnetic Spectrometer, a detector used in particle physics installed since 19 May 2011 on the International Space Station. It is designed for the research of new types of particles (antimatter, dark matter, strange matter) through the high-precision measurement of the composition of cosmic rays. Its measures will help scientists understand the laws behind the formation of the universe.

Editorial work and publications

Publishing activities and publications she is the author of numerous international publications, including:

 

(2018) Gentile S. , ATLAS [ATLAS Collaboration, Authors: 2856], Observation of Higgs boson production in association with a top quark pair at the LHC with the ATLAS detector, Phys. Lett. B 784 (2018) 173.

(2018) Gentile S. , ATLAS [ATLAS Collaboration, Authors: 2856],  Evidence for the associated production of the Higgs boson and a top quark pair with the ATLAS detector,Phys.Rev. D97 (2018) no.7, 072003.

(2017) Gentile S. , ATLAS Search for the dimuon decay of the Higgs boson in pp collisions at √s = 13 TeV with the ATLAS detectorPhys. Rev. Lett. 119 (2017) 051802

(2016) Gentile S.,ATLAS & CMS Collaboration, Measurements of the Higgs boson production and decay rates and constraints on its couplings from a combined ATLAS and CMS analysis of the LHCppcollision data ats=7 and 8 TeV, JHEP 08 (2016) 045

(2015) Gentile S.,ATLAS Search for the associated production of the Higgs boson with a top quark pair in multilepton final states with the ATLAS detector, Physics Letters B 749 (2015) 519-541

(2013) Corcella G, Gentile S. Heavy Neutral Gauge Bosons at LHC in an Extended MSSM.Nuclear Physics B, 866:293-366.
(2012) Gentile S. Z 'production at LHC in an extended MSSM.Proceedings of Science, 36th International Conference on High Energy Physics, Melbourne, Australia.
(2012) Gentile S. Phenomenology of new heavy neutral gauge bosons in an extended MSSM. Nuovo Cimento C, 035:349-360.
(2012) Aad et al. [ATLAS Collaboration, Authors: 2932]. Observation of a new particle in the search for the Standard Model Higgs boson with the ATLAS detector at the LHC"G. Physics Letters B 716, 1.
(2010) Gentile S. Systematics in charged Higgs search in ATLAS. Proceedings of Science, Third International Workshop on Prospects for charged Higgs Discovery at colliders-CHARGED2010, Uppsala, Sweden.
(2009) Gentile S. ATLAS search for MSSM Higgs bosons decaying into SUSY cascades. ATLAS Collaboration, ATL-PHYS-PUB-2009-079.
(2009) Gentile S. The ATLAS discovery potential for MSSM neutral Higgs bosons decaying into muon, tau. supersymmetric particle pairs. Balkan Physics Letters 16:109-113. Proceedings International Conference on Particle Physics in Memoriam Ergin Arik and Her collegues, Istanbul,Turkey.
(2008) Gentile S. ATLAS MSSM Higgs search in SUSY cascade. Proceedings of Science, Prospects for Charged Higgs Discovery at Collider, Uppsala, Sweden.
(2008) Fidecaro M, Gentile S. Il tassello mancante - la particella di Higgs. Giornale di Fisica, 49(2).
(2008) Gentile S. Detect MSSM neutral Higgs bosons at LHC. Proceedings Les Rencontres de physique de La Valle d'Aoste, La Thuile, 497-518.
(2007) Gentile S, Bilokon H, Chiarella V, Nicoletti G. The ATLAS discovery potential for MSSM neutral Higgs bosons decaying to a mu+mu- pair in the mass range up to 130 GeV. The European Physical Journal C, 229-245.

 

Raffaella Giavazzi
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STEM area: Biomedical sciences and biotechnology

Competences: oncological biology, pharmacology, translational research

Keywords: angiogenesis, anticancer drugs, cancer, ovarian cancer, tumor metastases

Region: Lombardy


Position/Role

Research Coordinator, Mario Negri Institute, Milan

Professional career

She obtained a Biological Sciences degree at the University of Milan, Italy, and then the qualification to practice as a biologist. She continued her studies with a PhD in Biology and Pharmacology at the Post-graduate School of Professional Education at the Mario Negri Institute and achieved her residency in Pharmacology at the University of Milan.

She spent several years abroad, in the US, where she worked as a post-doc Fellow in the Cancer Metastasis and Treatment Laboratory, NCI-FCRDC, Frederick (MD) and as Assistant Professor at the Dept. of Cell Biology of M.D. Anderson Hospital and Tumour Institute, University of Texas in Houston.

She is Head of the Laboratory of Cancer Metastasis Therapeutics at the Mario Negri Institute for Pharmacological Research since 1986, and starting from October 2018 she is the Research Coordinator of the Mario Negri Institute in Milan.

She was President of the Italian Cancer Society (2005-2007), in the board of the European Association for Cancer Research (2008-2012) and in the Board of Directors at the University of Trento (2012-2018).

Scientific results

Raffaella Giavazzi’s research interests are in the field of tumor biology and pharmacology with a specific interest in the metastatic process and tumor angiogenesis. She is involved in the pre-clinical and clinical development of new therapeutics against cancer, with particular involvement in ovarian and pancreatic cancer.

Editorial work and publications

Raffaella Giavazzi has published approximately 200 articles in the field of Cancer Research, including:
(2018) Resovi A, Bani MR, Porcu L, Anastasia A, Minoli L, Allavena P, Cappello P, Novelli F, Scarpa A, Morandi E, Falanga A, Torri V, Taraboletti G, Belotti D, Giavazzi R. Soluble stroma-related biomarkers of pancreatic cancer.Embo Molecular Medicine, 10(8), pii: e8741, doi: 10.15252/emmm.201708741.

 (2016) Cesca M, Morosi L, Berndt A, Fuso Nerini I, Frapolli R, Richter P, Decio A, Dirsch O, Micotti E, Giordano S, D’Incalci M, Davoli E, Zucchetti M, Giavazzi R. Bevacizumab-induced inhibition of angiogenesis promotes a more homogeneous intratumoral distribution of paclitaxel, improving the antitumor response. Molecular Cancer Therapeutics,15(1):125-35.
(2014) Ricci R, Bizzaro F, Cesca M, Guffanti F, Ganzinelli M, Decio A, Ghilardi C, Perego P, Fruscio R, Buda A, Milani R, Ostano P, Chiorino G, Bani MR, Damia G, Giavazzi R. A platform of patient-derived tumor xenografts (EOC-xenografts) to recapitulate the clinicopathology and genetic alterations of ovarian cancer. Cancer Research, 74(23):6980-90.
(2013) Rovida A, Castiglioni V, Decio A, Scarlato V, Scanziani E, Giavazzi R, Cesca M. Chemotherapy counteracts metastatic dissemination induced by antiangiogenic treatment in mice.Molecular Cancer Therapeutics, 12(10):2237-47.
(2012) Moschetta M, Pretto F, Berndt A, Galler K, Richter P, Bassi A, Oliva P, Micotti E, Valbusa G, Schwager K, Kaspar M, Trachsel E, Kosmehl H, Bani MR, Neri D, Giavazzi R. Paclitaxel enhances the therapeutic efficacy of the F8-IL2 immunocytokine to EDA-fibronectin positive metastatic human melanoma xenografts. Cancer Research, 72(7):1814-24.

Awards and prizes

Researcher Career Award “Lega Italiana per la lotta contro i tumori” (2003); “Giorgio Prodi” Lecturship, Italian Cancer Society (2012); Top Italian Women Scientists 2016; Researcher Career Award “5th Simon Karpatkin Memorial Lecture” (2018).

Maria Rita Gismondo
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STEM area: Biomedical sciences and biotechnology

Competences: microbiology

Keywords: anthrax, bioemergencies, bioterrorism, ebola, infections, microbiology, migrants, pandemics, virology

Region: Lombardy


Position/Role

Associate Professor of Clinical Microbiology, Medical School, University of Milan, Italy and Director of the Depart. of Clinical Microbiology, Virology and Bioemergency. Expert of the Italian Ministry of Foreign Affairs and International  Cooperation – BWC/ISU partner coordination and engagement strategy

 

Professional career

Degree in Biology, University of Catania (Italy) Degree in Medicine and Surgery, University of Catania 

(Italy) 

Specialization in Microbiology and Virology

Intern and Junior Resident in Clinical Microbiology, London   Hospital, London, UK

Intern and Junior Resident in Oral Microbiology, London   Hospital Medical School for Dentistry

Intern in Microbiology, Tennessee University, USA

Associate Professor of Clinical Microbiology University of Catania  

Associate Professor of Clinical Microbiology University of Milan

Expert of Bioemergency at Geneve UN - BWC Implementation

 

Editorial work and publications

 270 Publications in Peer-Reviewed Journals

Awards and prizes

Angelo dell'anno

Ambrogino d'Oro - Comune di Milano

 

Monica Gori
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STEM area: Psychology and neurosciences

Competences: experimental psychology

Keywords: bracelet, learning, low vision, motor system, perception, rihabilitation, sensory system, visual disabilities, visually impaired children, visual perception

Region: Liguria


Position/Role

Tenure Track Researcher U-Vip Unit dell'Istituto Italiano di Tecnologia (ITT) di Genova, coordinator of the european projects ABBI and WeDraw

Professional career

Monica Gori graduated in Psychology at the University of Florence in 2004 (cum laude). From 2002 to 2006 she worked at the within the VisionLab of the CNR of Pisa in David Burr’s Laboratory. In 2008 she worked in Martin Banks lab (Berkeley, California). She did her PhD in January 2009 at University of Genoa on Humanoid Technologies supervised by David Burr and Giulio Sandini. Currently Monica Gori is Tenure Track Researcher, leading the Unit for people with visual disabilities (U-Vip Unit) at the Italian Institute of Technology of Genoa.

Scientific results

Monica Gori is expert of development, multisensory integration, sensorial-motor perception and visual disability. Through her research, she studies how the sensory and multi-sensorial perception skills interact during development in children with and without disabilities. The aim of her study is to exploit this knowledge to better understand brain functions, create new rehabilitation programs and to develop new technological solutions to improve the perceptual, motor and social skills of children with sensory disabilities. From 2014 to 2017 she coordinated the European ABBI project (www.abbi.eu), whose aim is precisely the development of a new technology based on sensory-motor rehabilitation for blind and low vision children. The project involves the study and creation of a wearable sound device, similar to a bracelet, also useful for creating sound networks to be placed in environments where the blind are living, thus allowing the hearing, and not the sight, to create a spatial map in which the person can move. From 2017 to 2018 she coordinated the weDRAW European project (www.wedraw.eu) in which she proposed to develop a multisensory approach and technology for learning mathematical skills at the elementary school. weDRAW involved children and teachers in Italy, UK and Ireland. WeDraw is highly interdisciplinary,  involving engineers, psychologists, pedagogics, and industrial links. The project exploits knowledge of multisensory integration in the teaching activity of elementary schools.

Editorial work and publications

Monica Gori is the author of book chapters and numerous scientific articles in international journals, including:

 

(2018) Gori, Amadeo, Campus Temporal cues influence space estimations in visually impaired individuals. iScience, vol. 6, pp. 319-326
(2018)Campus, Sandini, Concetta Morrone, & Gori. Spatial localization of sound elicits early responses from occipital visual cortex in humans. Scientific Report
(2017) Gori, Cappagli, Tonelli, Baud-Bovy, Finocchietti. Devices for visually impaired people: high technological devices with low user acceptance and no adaptability for children Neuroscience & Biobehavioral Reviews
(2017) Gori, Cappagli, Baud-Bovy, & Finocchietti. Shape Perception and Navigation in Blind Adults.Frontiers  in Psychology
(2017)Cappagli, Cocchi, & Gori. Auditory and proprioceptive spatial impairments in blind children and adults. Developmental Science, 2017
(2016)  Cuturi, Aggius-Vella, Campus, Parmiggiani, and Gori. From science to technology: orientation and mobility in blind children and adults. Neurosci and Biobe. Reviews 2016,impact factor 10.5 citations 2 (2016) Cappagli G, Gori M. Auditory spatial localization: Developmental delay in children with visual impairments. Research in Developmental Disabilities, 53-54:391-8.
(2016) Tonelli A, Brayda L, Gori M. Depth echolocation learnt by novice sighted people. PLoS ONE, 11(6):e0156654.
(2016) Vercillo T, Burr D, Gori M. Early visual deprivation severely compromises the auditory sense of space in congenitally blind children. Developmental Psychology, 52(6):847-53.
(2015) Finocchietti S, Cappagli G, Porquis LB, [...], Cocchi E, Gori M. Evaluation of the Audio Bracelet for Blind Interaction for improving mobility and spatial cognition in early blind children - A pilot study. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS.
(2015) Magnusson C, Rydeman B, Finocchietti S, [...], Baud-Bovy G, Gori M. Co-located games created by children with visual impairments. MobileHCI 2015, Proceedings of the 17th International Conference on Human-Computer Interaction with Mobile Devices and Services Adjunct.
(2015) Tinelli F, Anobile G, Gori M, [...], Cioni G, Concetta Morrone M. Time, number and attention in very low birth weight children. Neuropsychologia, 73:60-9.
(2015) Vercillo T, Gori M. Attention to sound improves auditory reliability in audio-tactile spatial optimal integration. Frontiers in Integrative Neuroscience, 9:34.
(2015) Gori M. Multisensory integration and calibration in children and adults with and without sensory and motor disabilities. Multisensory Research, 28(1-2):71-99.
(2015) Gori M, Hanganu-Opatz IL. Introduction to the special issue on multisensory development and plasticity. Multisensory Research, 28, 1-2, 31-32.
(2015) Vercillo T, Burr D, Sandini G, Gori M. Children do not recalibrate motor-sensory temporal order after exposure to delayed sensory feedback. Developmental Science, 18(5):703-712.

Awards and prizes

(2008) F1000 with the article "Gori et al. 2008; Young children do not integrate visual and haptic form information. Curr Biol, 18(9)"
(2012) TR35 Giovani Innovatori
(2015) Smart Cup Liguria October 2015 Cup for new technological solutions and start-up

 

Maria Luisa Gorno Tempini
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STEM area: Psychology and neurosciences

Competences: behavioural neurology

Keywords: Alzheimer, aphasia, dyslexia, language, learning disabilities, neuro degenerative diseases, neuroscience, reading, syntax

Region: ABROAD


Position/Role

Professor of neurology and psychiatry at University of California, San Francisco with a specialty in behavioral neurology and a PhD in neuroscience

Professional career

She specializes in understanding the neural basis of higher cognitive function with a specific interest in speech and language across the lifespan. She directs the Language Neurobiology Laboratory of the UCSF Memory and Aging Center. Dr. Gorno Tempini also co-founded the UCSF Dyslexia Center in 2015 and is a co-director of the center.

Scientific results

At the Dyslexia Center, she leads a large multidisciplinary team of clinicians and scientists with expertise in behavioral neurology, cognitive neuroscience, speech-language pathology and advanced neuroimaging techniques. Her work in neurodevelopmental disorders aims at discovering the distinct clinical and biological phenotypes of dyslexia and the best approach to diagnose and remediate them.

Editorial work and publications

Dr. Gorno Tempini has authored over 170 peer-reviewed papers on the neurobiology of language disorders in scientific journals and has been invited to speak at conferences across the globe, including the American Academy of Neurology and the Italian Senate.

Awards and prizes

She is the current recipient of multiple National Institute of Health projects grants and has received a prestigious career award for mentoring scientists and clinicians on the neurobiology of language at UCSF. In 2017, she received a Weill Institute for Neurosciences Trailblazer award to study language development in children, and in 2018, she was distinguished as the Charles Schwab Endowed Professor in Dyslexia and Neurodevelopment.

Emanuela Guidoboni
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STEM area: Natural and environmental sciences

Competences: historical seismology

Keywords: anti-seismic systems, archeology, climate, earthquakes, eedis, extreme events, history, seismic disasters, tsunamis, volcanoes

Region: Emilia-Romagna


Position/Role

Coordinator of the multidisciplinary activities of the Euro-Mediterranean Documentation Center for Extreme Events and Disasters

Professional career

After graduating in History at the University of Bologna, she has been developing research on earthquakes, tsunamis and volcanic eruptions concerning Italy and the Mediterranean area for thirty years, with a specific focus on Earth Sciences and Engineering . Emanuela Guidoboni carries out her research activity as a manager of national projects and as a scholar. From 1983 to 2007 she was President and scientific director of the research company SGA, History of Geophysics Environment of Bologna. From 2007 to 2011, she has been a senior research director at the National Institute of Geophysics and Volcanology (INGV). Since 2012 she has coordinated the multidisciplinary activities of EEDIS, the "Euro-Mediterranean documentation center for extreme events and disasters", aimed at both scientific dissemination and new research.

Scientific results

From 1983 to 1987, as part of the studies for the National Energy Plan, she directed SGA's historical research aimed at studying over 1,700 earthquakes from the ancient world to the 20th century, preparing research programs and final elaborations, managed by a bank specific data (the first in Italy). From 1987 to 1990 she directed the national GIANO project for ENEA, with the aim of studying extreme climatic events (rainfall, drought, floods and landslides) to outline a history of climate in Italy from the 11th to the 19th century. The historical sources relating to the eighteenth and nineteenth centuries were used for the AVI project (Italian Vulnerated Areas) of the IRPI-CNR, available online, together with the data entered in the ISPRA database on historic landslides. From 1987 to 2005 she directed national projects for historical research aimed at the database of the Strong Earthquake Catalog in Italy from the ancient world to the twentieth century for INGV (National Institute of Geophysics and Volcanology). In this context she has developed numerous specific researches on the evaluation of parameters connected to clusters of highly destructive earthquakes, on the characteristics of historical buildings, on pre-modern anti-seismic systems and on reconstructions from the point of view of social, economic and urban history.

 

 

Editorial work and publications

She is the author of numerous publications, including:

 

(2016) Guidoboni E. Erdbeben und Seebeben im antiken Mittelmeerraum. Gründe für einen Dialog zwischen Seismologie und Geschichte. Erdbeben in der Antike, Deutungen – Folgen – Repräsentationen, herausgegeben von Borsch J & Carrara L, Mohr Siebec, Tubingen Univ,15- 26. (2016) Guidoboni E. Effetti, rimedi e propagazione dei terremoti: Nota su un trattato (1571) e una dissertazione (1669). Storia dell’Ingegneria, a cura di S. D’Agostino, Sesto convegno Nazionale di Storia dell’Ingegneria, Napoli, 321-337.

(2015) Guidoboni E, Valensise G. On the complexity of earthquake sequences: a historical seismology perspective based on the L'Aquila seismicity (Abruzzo, Central Italy). 1315-1915. Earthquakes and Structures, 8(1):153-184. (2015) Dalai M, Guidoboni E (a cura di). La tutela alla prova dei terremoti. Il patrimonio storico e artistico fra restauri, ricostruzioni e perdite. Numero monografico di “Economia della cultura”, Il Mulino, Bologna, anno XXIV, 3, 4. (2015) Guidoboni E. Terremoti e Città in una prospettiva di lungo periodo. Economia della cultura, Il Mulino, Bologna, anno XXIV, n.3-4, 284-294. (2015) Guidoboni E. Che cosa è il Catalogo dei Forti Terremoti in Italia. Economia della cultura, Il Mulino, Bologna, anno XXIV, 3,4: 421-428.

(2015) Guidoboni E. When Towns Collapse: Images of Earthquakes, Floods, and Eruptions in Italy in the Fifteenth to Nineteenth Centuries. Wounded Cities: The Representation of Urban Disasters in European Art (XIV–XX Centuries), edited by M.Folin and M.Preti, Chap.2, Koninklijke Brill, NY– Leiden: 33-56. (2015) Guidoboni E, Terremoti e Storia trenta anni dopo. Quaderni Storici, numero monografico “Storia Applicata”, (a cura di) Torre A, 3, 753-784. (2015) Guidoboni E, Comastri A. The earthquakes of Aleppo and the region of “deadcities” (Syria) 7th–15th century. The Dead Cities of Northen Syria and their Demise , T. Riis editor, Publications of the Danish Institute of Damascus, X: 61-110.

 

She is also the author of books and monographs including:

 

Guidoboni E, Mulargia F, Teti V, (a cura di), Prevedibile / Imprevedibile. Eventi estremi nel prossimo futuro, editore Rubbettino, 2015, pp. 358.

Guidoboni E, Ciuccarelli C, Mariotti D, Comastri A, Bianchi MG, L’Etna nella Storia. Catalogo delle eruzioni dall’antichità alla fine del XVII secolo, INGV, Bononia University Press, Bologna, 2014, pp. 1152.

Guidoboni E e Valensise G (a cura di), L’Italia dei disastri. Dati e riflessioni sugli impatti degli eventi naturali (1861-2013). Centro EEDIS-INGV, Bononia University Press, Bologna, 2014, pp. 432.

 

 

 

Awards and prizes

In 2004 she was appointed member of the Academia Europaea for the multidisciplinary approach to seismic and volcanic hazards and in 2009 she published the first historical seismology manual with John Ebel: Earthquakes and Tsunamis in the Past. A Guide to Techniques in Historical Seismology (Cambridge). In 2016 she won the first Maiella Prize for Essays.

 

Paola Inverardi
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STEM area: Computer science

Competences: computer technology

Keywords: computer technology, rector, software architecture, software engineering

Region: Abruzzo


Position/Role

Dean of the University of L’Aquila.

Professional career

In 1981 she graduated in Information Science at the University of Pisa. In the same year she entered the Olivetti with the role of Researcher that she also maintained during the decade 1984-1994 at the CRN of Pisa. In 1994 she became full professor of computer science at the University of L'Aquila, where she later held various prestigious roles in university governance: from 1994 to 2000 she was Chairman of the Computer Science Degree Course and later Director of the Computer Science Department. In 2008 she became Dean of the Faculty of Mathematical, Physical and Natural Sciences of the same university. From July 2012 to September 2013 she directed the Department of Engineering and Information Sciences and Mathematics (DISIM). Paola Inverardi was elected Director of the University of L'Aquila in the 2013/2014 academic year, a position she would hold until 31 October 2019.

Scientific results

Her main interests concern software engineering, with particular attention to the area of software architectures, which include, in addition to the structure organization of the system itself, the ways in which the different parts integrate and interact to form a single unit. In this context, she was involved in the analysis and check of both behavioral and quantitative architectural properties for distributed and mobile systems based on components. She is also actively involved in collaborating with important information technology and telecommunications industries.She regularly works as reviewer for international research agencies, foreign universities and the European Commission.

 

Editorial work and publications

She is author of numerous national and international publications, including:

(2011) Cortellessa V, Di Marco A, Inverardi P. Model-Based Software Performance Analysis. Springer 2011, isbn 978-3-642-13620-7. 

(2009) Pelliccione P, Inverardi P, Muccini H. CHARMY: A Framework for Designing and Verifying Architectural Specifications. IEEE Transactions on Software Engineering, 35(3):325-346. 

(2004) Balsamo S, Di Marco A, Inverardi P, Simeoni M, Model-Based Performance Prediction in Software Development: A Survey. IEEE Transactions on Software Engineering, 30(5):295-310. 

(2004) Muccini H, Bertolino A, Inverardi P, Using Software Architecture for Code Testing. IEEE Transactions on Software Engineering, 30(3):160-171. 

(2003) Inverardi P, Tivoli M, Deadlock-free software architectures for COM/DCOM Applications. Journal of Systems and Software, 65(3):173-183. 

(2001) F Aquilani, S Balsamo, P Inverardi: Performance analysis at the software architectural design level. Performance Evaluation, 45(2):147-178. 

(2000) Inverardi P, Wolf AL, Yankelevich D, Static checking of system behaviors using derived component assumptions. ACM Transactions on Software Engineering and Methodology, 9 (3), 239-272. 

(1995) Inverardi P, Nesi M, Deciding observational congruence of finite-state CCS expressions by rewriting Theoretical Computer. Science, 139(1):315-354. 

(1995) Inverardi P, Wolf AL, Formal specification and analysis of software architectures using the chemical abstract machine model. IEEE transactions on Software Engineering, 21(4):373-386. 

(1993) Inverardi P, Mazzanti F, Experimenting with Dynamic Linking with Ada. Software: Practice and Experience, 23(1):1-14.

Awards and prizes

In May 2011 she  gained an honorary PhD from Mälardalen University in Sweden and, in 2013, the IEEE TCSE Distinguished Service Award "for outstanding and sustained contributions to software engineering community". Moreover she is also a member of the ACM Europe Council and of the European Academy.

 

 

Caterina La Porta
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STEM area: Biomedical sciences and biotechnology

Competences: biophysics, cellular biology, computational analysis, molecular biology, systems biology

Keywords: cancer stem cells

Region: Lombardy


Position/Role

Associate professor of general pathology at the University of Milan, group leader of the Molecular Oncology Lab, founding member of the Center for Complexity and Biosystems, University of Milan.

Professional career

After graduating in medicine in 1989 at the University of Milan and in 1995 she received a Ph. D. in physiology from the same university. 

From 1990 and 1991, she worked at the Institute for Pharmacological Research Mario Negri in Milan and spent nine months at the Karolinska Institutet in Sweden. From 1993 to 1994, she worked at the German Cancer Research Center (DKFZ) in Heidelberg and then in 1995 she spent five months at the Rockefeller University in New York. From 1994 to 1997 she was a fellow of  the Associazione Italiana per la Ricerca sul Cancro (AIRC). She came back to the University of Milan in 1997 and obtained tenure in 2002. 

 

Scientific results

In 2015, she co-founded the Center for Complexity and Biosystems at University of Milan, where she studies the

fundamental mechanisms driving an healthy cell to become cancerous. In the specific case of melanoma, a very aggressive tumor that is hard to treat, here research activity lead to the discovery of a cellular subpopulation denoted as cancer stem cells (CSC).  According to her research, all melanoma cells can transform into CSC when the number of CSC falls  below a critical threshold, an effect due to the activation of a complex network on non coding microRNA. The result of this mechanism is that the number of CSC inside a tumore is held constant. This discovery might lead to reconsider the conventional therapeutic approach to cancer by eliminating the CSC that are feeding tumor growth. The current objective of Caterina La Porta’s  research is now to explore if the CSC is the correct model to describe melanoma progression, using an interdisciplinary approach combining cancer biology, theoretical physics and clinical studies, and to investigate if it is a universal model that can be used

for other tumors as well. The long term goal of her research is to understand highly complex systems integrated into the human body.

An additional research line focuses on the study of neurodegenerative diseases, in particular on the understanding of protein aggregation such as beta amyloid or neuroserpin and on the development of innovative diagnostic techniques.

Editorial work and publications

She is the author of many international publications among which:

 

(2018)F. Font-Clos, S. Zapperi, C. A. M La Porta. Topography of epithelial-mesenchymal plasticity, PNAS 115 5902-5907.

 (2018) O. Chepizhko, M. C. Lionetti, C. Malinverno, G. Scita, S. Zapperi , C. A. M. La Porta

From jamming to collective cell migration through a boundary induced transition. Soft

Matter 14 (19), 3774-3782

(2018) F.Font-Clos, S. Zapperi, CAM La Porta Gene expression signature of obesity in

monozygotic twins. Physiol Meas. 39, 044008, 2018. doi: 10.1088/1361-

6579/aab85a.

(2017)F Font-Clos, S. Zapperi, C.A.M. La Porta Integrative analysis of pathway deregulation in obesity. Nature Publishing group: Systems Biology and Applications 3:18.

(2017) Z. Bertalan, S. Zapperi, C. A. M. LaPorta, Modeling mechanical control of spindle orientationof intestinal crypt stem cells Journal of Theoretical Biology 430, 103–108.

(2017)F Font, S. Zapperi, C.A.M. La Porta Integrative analysis of pathway deregulation in

obesity. Nature Publishing Journal Systems Biology and Applications 3:18 ;

doi:10.1038/s41540-017-0018-z.

(2017) C. Giampietro, MC Lionetti, G. Costantini, F. Mutti, S. Zapperi, CAM La Porta

Cholesterol impairment contributes to neuroserpin aggregation. Scientific Reports 7, 43669,

(2016)O. Chepizhko, C. Giampietro, E. Mastrapasqua., M. Nourazar, M. Ascagni, M. Sugni,

U. Fascio, L. Leggio, C. Malinverno, G. Scita, S. Santucci, M. J. Alava., S. Zapperi,

C.A.M. La Porta. Burst of activity in collective cell migration PNAS 113, 11408–11413

(2015)A. L. Sellerio, E. Ciusani, N. Bossel Ben-Moshe, S. Coco, A. Piccinini, C. R. Myers, J.

P. Sethna, C. Giampietro, S. Zapperi, C. A. M. La Porta Overshoot during phenotypic

switching of cancer cell populations Scientific Reports 5, 15464, doi:10.1038/srep15464,

(2015)A. Taloni, E. Kardash, O. U. Salman, L. Truskinovsky, S. Zapperi, C. A. M. La Porta,

Volume changes during active bleb fluctuation in cells Physical Review Letters 114, 208101,

(2014) Z. Budrikis, G. Costantini, C. A. M. La Porta, S. Zapperi, Protein accumulation in the

endoplasmic reticulum as a non-equilibrium phase transition. Nature Communications 5

3620, 2014

(2012) C. A. M. La Porta, S. Zapperi, J. P. Sethna Senescent cells in growing tumors: population dynamics in cancer stem cells. Plos Computational Biology 8, e1002316.

Cecilia Laschi
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STEM area: Computer science

Competences: biorobotics

Keywords: i-droid, neuro development bioengineering, octopus project, robot

Region: Tuscany


Position/Role

Professor at the BioRobotics Institute of Scuola Superiore Sant'Anna, Pisa, Rector’s delegate to Research, Vice-Director of the BioRobotics Institute

Professional career

After a Master Degree in Computer Science at the Unversity of Pisa in 1993, she obtained a PhD in Robotics from the University of Genova in 1998. From the following year she was Post-doc research assistant at Scuola Superiore Sant’Anna in Pisa. From 2000 to 2006 she was Assistant Professor of Biorobotics at Scuola Superiore Sant’Anna and in 2001-2002 she was visiting researcher at the Humanoid Robotics Institute of Waseda University di Tokyo, Japan. Since 2006 she was Associate Professor and since 2014 Full Professor of Biorobotics at Scuola Superiore Sant’Anna.

Scientific results

Cecilia Laschi’s research interest is Biorobotics. Starting from experiences in basic robotics, she investigated bioinspired solutions for service robotics. Recently, she worked on an ambitious project grown in a tank at the Research Centre on Sea Technologies and Marine Robotics in Livorno, where the model was a common octopus, Octopus vulgaris. Studying this cephalopod’s movement, in the OCTOPUS European project, Cecilia Laschi and her team put the basis for the biomimetics of the future: designing and developing bioinspired robots, built with soft materials. The first prototype of soft robot arm imitates the muscular structure of the octopus arm and is built with siliconic materials, thanks to novel actuators giving a contraction of the muscular structure and a special braided structure inspired to the octopus connective tissue, covered by a an artificial skin with suckers. The robot arm works in water because, similarly to the octopus, it uses the mechanics of the interaction with water, mimicking the octopus arm bending and the elongation. The technologies developed by mimicking the octopus are now finding further development in many projects on several applications, ranging from marine explorations to the biomedical field, in surgery and assistance to the elderly. This research brought to the development of the new research area of soft robotics, at international level.

Cecilia Laschi’s name is also linked to another important project: in 2007 she contributed to the birth, in Tokyo, of the “RoboCasa” joint lab of Scuola Superiore Sant’Anna and Waseda University, where Italian and Japanese researchers could work together in frontier research. Related to her expertise in humanoid robotics is the birth of iDroid01, produced by a spin-off company of Scuola Superiore Sant’Anna, RoboTech srl, that she founded. iDroid01 is the first personal robot sold in parts to assemble, in eight countries, able to speak, understand basic commands, see, move its head following sounds, show feelings and especially learn, by storing behaviour schemes.

Laschi is among the inventors of another achievement of robotics in Pisa: DustBot, the dustmen robots. DustClean, which swaps street with brushes and sprays, and DustCart, a “snowman” coloured in green or blue, with two wheels, which comes to the doorstep upon call, open its stomach-drawer, receives the garbage bag and brings it out of the historical city centre. The two Italian Wall-es – on which Laschi has been worked from 2006, also with RoboTech srl – have been already put in service in an experimental session in a small village in Tuscany.

Editorial work and publications

Cecilia Laschi is author of many publications in international scientific journals (see http://www.santannapisa.it/en/personale/cecilia-laschi for the complete list), among which:

(2019) T. George Thuruthel, B. Shih, C. Laschi, M. Tolley, “Soft robot perception using embedded soft sensors and recurrent neural networks”, Science Robotics 4(26).

(2018) M. Cianchetti, C. Laschi, A. Menciassi, P. Dario, “Biomedical applications of soft robotics”, Nature Reviews Materials, 3(6), pp.143-153.

(2018) T. George Thuruthel, Y. Ansari, E. Falotico, C. Laschi, “Control Strategies for Soft Robotic Manipulators: A Survey”, Soft Robotics 5(2), pp.149-163.

(2017) C. Laschi, “Helping robots blend into the background”, Science, 358(6360), p.169.

(2017) E. Falotico, A. Berthoz, P. Dario, C. Laschi, “Sense of movement: Simplifying principles for humanoid robots”, Science Robotics, 2(13).

(2016) Laschi C, Mazzolai B. Lessons from nature: the symbiosis of morphological computation and soft robotics. IEEE Robotics & Automation Magazine 23. 
(2016) Calisti M, Falotico E, Laschi C. Hopping on Uneven Terrains With an Underwater One-Legged Robot. IEEE Robotics and Automation Letters,1.1:461-468. 
(2016) Cianchetti M, Laschi C. Pleasant to the Touch: By Emulating Nature, Scientists Hope to Find Innovative New Uses for Soft Robotics in Health-Care Technology. IEEE Pulse, 7(3):34-37. 
(2016) Cauli N, Falotico E, Bernardino A, Santos-Victor J, Laschi C. Correcting for Changes: Expected Perception-Based Control for Reaching a Moving Target. IEEE Robotics and Automation Magazine, 23(1):63-70. 
(2015) Cianchetti M, Calisti M, Margheri L, Kuba M, Laschi C. Bioinspired locomotion and grasping in water: the soft eight-arm OCTOPUS robot. Bioinspiration & Biomimetics, 10, 035003. 
(2015) Renda F, Giorgio-Serchi F, Boyer F, Laschi C, Modelling cephalopod-inspired pulsed-jet locomotion for underwater soft robots. Bioinspiration and Biomimetics, 10(5). 
(2015) Calisti M, Corucci F, Arienti A, Laschi C. Dynamics of underwater legged locomotion: Modeling and experiments on an octopus-inspired robot. Bioinspiration and Biomimetics, 10(4). 
(2014) Renda F, Giorelli M, Calisti M, Cianchetti M, Laschi C. Dynamic Model of a Multibending Soft Robot Arm Driven by Cables. IEEE Transactions on Robotics, 30, 1109-1122. 
(2014) Laschi C, Cianchetti M. Soft Robotics: New Perspectives for Robot Bodyware and Control. Frontiers in Bioengineering and Biotechnology, 2. 
(2013) Kim S, Laschi C, Trimmer B. Soft robotics: a bioinspired evolution in robotics. Trends in Biotechnology, 31, 287-294.

Awards and prizes

Co-founder in 2004 of the “RoboTech srl” academc spin-off company of Scuola Superiore Sant'Anna, in the field of edutainment robotics. Co-author of sixteen patents, in Italy, Europe, Japan.

 

Sandra Leone
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STEM area: Physics

Competences: experimental elementary particle physics

Keywords: antiproton, atlas experiment, boson w, CERN, collision, elementary particles, fermilab, higgs boson, proton, top quark

Region: Tuscany


Position/Role

Senior researcher at National Institute for Nuclear Physics (INFN) in Pisa (Italy)

Professional career

Sandra Leone obtained a master degree in physics from Pisa University in 1990 and a PhD from the same University in 1994. After a 2 years post-doc position, in 1997 she enters INFN-Pisa as researcher in experimental high energy physics. Since 2009 she is senior researcher in the same institute. She has the full professor qualification  (required to cover full professor positions in Italy). Since 2005 she is responsible for the organization of the Pisa European Particle Physics Masterclass for high school students. She was in the local organizing committee of 6 international congresses and was in charge of the organization of INFN local scientific seminars since 2002 until 2008.

Scientific results

Sandra Leone’s field of research is experimental particle physics. In 1989 she starts studying proton-antiproton collisions in the CDF experiment at the Fermilab Tevatron Collider, in the US. In particular she studied the production mechanism of the W boson. In 1994-1995 she studied the top quark production and was part of the team which observed for the first time the top quark in the CDF experiment. From 1997 to 2001 she works with silicon detectors and studies their application in experiments at hadron colliders. In particular, she is responsible in this period of the construction and test of 161 elementary units of the ISL silicon detector for the CDF experiment. In the following years she commits herself to the study of associated production of WZ intermediate bosons and the search for the Higgs boson.

In 2013 she joins the ATLAS experiment at CERN. She takes part to the construction and test of the new laser calibration system for the ATLAS hadron calorimeter. Since 2015 she studies the robustness and longevity of photomultiplier tubes, in the context of the foreseen upgrades of the ATLAS detector. She was invited to present scientific results on behalf of her collaborations in plenary session in  15 international conferences and in several national conferences, physics schools, seminars and conference parallel sessions, like ‘ichep2016’, one of the most important conferences in the field of high energy physics, which was held in Chicago

Editorial work and publications

She is referee of international journals and co-author of more than 1000 international papers, among which:

(2016) CDF Collaboration. Measurement of the WW and WZ production cross section using final states with a charged lepton and heavy-flavor jets in the full CDF Run II data set. Physical Review D, 94, 032008.

(2012) CDF Collaboration. Evidence for a Particle Produced in Association with Weak Bosons and Decaying to a Bottom-Antibottom Quark Pair in Higgs Boson Searches at the Tevatron. Physical Review Letters, 109, 071804.

(2007) CDF Collaboration. First Measurement of the Ratio of Central-Electron to Forward-Electron W Partial Cross Sections in proton-antiproton collisions at center of mass energy of 1.96 TeV. Physical Review Letters, 98, 251801.

(1995) CDF Collaboration. Observation of Top Quark Production in proton-antiproton collisions with the Collider Detector at Fermilab. Physical Review Letters, 74, 2626.
(1992) Abe F, [...] Leone S, et al. Lepton Asymmetry in W-boson Decays from proton-antiproton Collisions at center of mass energy of 1.8 TeV. Physical Review Letters, 68, 1458.

Awards and prizes

Sandra Leone held several prominent roles in her field and was part of several committees. In 1995 she received an award for young researchers from the Italian Physics Society (SIF). Since 1998 she is referee of Physical Review Letters and Physical Review D journals. Since 2013 she is member of the editorial staff of “Scienza per tutti”, the official outreach web site of INFN. Since 2008 she acted in several occasions as independent expert  evaluator for the European Seventh Framework Program and Horizon2020. From 2006 to 2011 she was part of the INFN Equal Opportunity Committee.

Sonia Levi
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STEM area: Biomedical sciences and biotechnology

Competences: cellular biology

Keywords: iron, protein engineering, proteins

Region: Lombardy


Position/Role

Associate Professor in Applied Biology, Vita-Salute San Raffaele University and Head of the "Proteomics of Iron Metabolism" Research Unit of the San Raffaele Scientific Institute of Milan.

 

Professional career

After graduating in Biological Sciences at the University of Milan in 1982, Sonia Levi continued her training in the Department of Biomedical Sciences and Technologies of the San Raffaele Hospital. In 1984, she obtained a fellowship from the European Molecular Biology Organization at the European Molecular Biology Laboratory in Heidelberg, Germany. Two years later, she received a three-year post-doctoral research fellow to continue her research activity and, in 1989, she was hired as a researcher in the "Iron Metabolism" Research Unit of the San Raffaele Scientific Institute. In 2003, she became the head of the Proteomic of Iron Metabolism Research Unit of the San Raffaele Scientific Institute of Milan. In 2005, she got the position of Associate Professor in Applied Biology, School of Medicine, Vita-Salute San Raffaele University.

Scientific results

Sonia Levi has been interested for years in the study of iron metabolism and associated diseases. When she was at the EMBL (European Molecular Biology Laboratory), she learned the pioneering techniques of recombinant DNA applied to protein expression. After returning to Italy, she imported these new methodologies to the "Iron Metabolism" laboratory of the San Raffaele Hospital in Milan, where she has been successful in obtaining the recombinant human ferritins and their mutants, useful in the study of the assembly of complex protein structures. From 1992 to 2002, she continued her research in the "Protein Engineering" laboratory at the Department of Biotechnological Research (DIBIT) of the San Raffaele Scientific Institute where she developed eucariotic cellular models overexpressing iron proteins to analyze their biological functions. In 2001 she identified and isolated a new human ferritin located in the mitochondrion (small cellular organelle). The biological and functional characterization of this new protein is one of its main topics of interest. Her recent research is focused to clarify the relationship between iron and neurodegeneration. With this aim, she developed and studied cellular and animal models of neurodegenerative disease, like neuroferritinophaty, PKAN and Friedreich's ataxia. More recently, she is applying the technology of cellular reprogramming to obtain human neuronal models for the disorders defined as Neurodegeneration with Brain Iron Accumulation.

Editorial work and publications

Author of more than one hundred Italian and international publications including:

(2016) Orellana DI, Santambrogio P, Rubio A, Yekhlef L, Cancellieri C, Dusi S, Giannelli SG, Venco P, Mazzara PG, Cozzi A, Ferrari M, Garavaglia B, Taverna S, Tiranti V, Broccoli V, Levi S. Coenzyme A corrects pathological defects in human neurons of PANK2-associated neurodegeneration. EMBO Molecular Medicine, 8 (10): 1197-1211.

(2013) Cozzi A, Santambrogio P, Privitera D, Broccoli V, Rotundo LI, Garavaglia B, Benz R, Altamura S, GoedeJS, Muckenthaler MU, Levi S. 2013. Human L-ferritin deficiency is characterized by idiopathic generalized seizures and atipica restless leg syndrome.Journal of Experimental Medicine, 210 (9): 1779-91.

(2001) Levi, S., Corsi, B., Bosisio, M., Invernizzi, R., Volz, A., Sanford, D., Arosio, P., Drysdale, J.A Human Mitochondrial Ferritin Encoded by an Intronless Gene. Journal of Biological Chemistry, 276 (27): 24437-24440.

 (1991) Lawson, D.M., Artymiuk, P.J., Yewdall, S.J., Smith, J.M.A., Livingstone, J.C., Treffry, A., Luzzago, A., Levi, S., Arosio, P., Cesareni, G., Thomas, C.D., Shaw, W.V., Harrison, P.M. Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts Nature, 349 (6309): 541-544.

(1988) Levi, S., Luzzago, A., Cesareni, G., Cozzi, A., Franceschinelli, F., Albertini, A., Arosio, P. Mechanism of ferritin iron uptake: Activity of the H-chain and deletion mapping of the ferro-oxidase site. A study of iron uptake and ferro-oxidase activity of human liver, recombinant H-chain ferritins, and of two H-chain deletion mutants. Journal of Biological Chemistry, 263 (34): 18086-18092.

 

Awards and prizes

2016-2018 Member of the “Top Italian Women Scientist”

2016 Member of “100 esperte”

 

Rita Lorenzini
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STEM area: Physics

Competences: plasma physics

Keywords: energy, ITER, thermonuclear fusion

Region: Emilia-Romagna


Position/Role

Lead researcher at Agenzia nazionale per le nuove tecnologie, l'energia e lo sviluppo economico sostenibile (ENEA)

Professional career

I got the Master ‘s degree in Physics in 1992 from Università degli Studi di Pisa, defending a thesis in particle physics based on studies performed at CERN, in Geneva. I obtained a research fellowship from the Istituto Nazionale di Fisica della Materia (INFM) on a research program in thermonuclear fusion physics and I started my collaboration with Consorzio RFX in Padua. The collaboration was maintained also when, in1993, I obtained a permanent position at ENEA.

Between 2000 and 2002 I spent several months at Max Planck Institut für Plasmaphysik in Munich to work on the tokamak experiment ASDEX Upgrade in the framework of Mobility Program funded by EURATOM.

In 2005 I got the PhD in Energetics from Università degli Studi di Padova. From 2006 I am lead researcher, always in ENEA.

Scientific results

My activity research is in the area of thermonuclear plasma physics, which aims at producing clean energy reproducing the physics processes that occur in the stars, like the Sun, in earth laboratories.

I work mainly on the Reversed Field Pinch experiment RFX-mod, located in Padua and operated by Consorzio RFX, a consortium of CNR, ENEA, INFN, Università di Padova and Acciaierie Venete.

I participate in several international collaborations, for example with the research team of the Madison Symmetric Torus experiment (MST) in Madison, Wisconsin (USA) and with the team of Large Helical Device (LHD) located  in Toki, Japan. More recently I started a collaboration with the Joint European Torus (JET) tokamak located in Culham, in UK.

I investigate the problem of particle and energy transport in thermonuclear plasmas through data analysis and development of numerical codes. I also contribute to the organization and realization of the experiments for the collection of data.

In 2008 I partecipated to the first observation of Single Helical Axis states (SHAx), the enhanced confinement states that occur when a toroidal RFP plasma is heated by a high current.

I devoted many efforts to characterize the transport barriers  observed in SHAx states and to clarify the relationship between the transport and the magnetic turbulence.

My recent research aims at exploiting  the results of solar physics, in particular of solar flares, to advance the comprehension of SHAx states.

The other important item of research regards so called ‘isotope effect’, namely the differences between plasmas of different hydrogen isotopes. I studied the isotope effect in RFX-mod and I participate in the isotope effect studies of JET and LHD.

Recently I worked in collaboration with LHD colleagues to the development of a code able to model plasmas with multiple magnetic axes. With the help of such code, named MAxS (Multiple Axis Solver) we will be able to study energy and particle transport in presence of magnetic islands

Editorial work and publications

I act as referee for plasma and general physics journals (Nuclear Fusion, Plasma Physics and Controlled Fusion and Physical Review Letters)

I was invited tom give a lecture titled  ‘Improvement of the magnetic configuration in the Reversed Field Pinch through successive bifurcations’ to the  50th Annual Meeting of the Division of Plasma Physics, American Physical Society nel Novembre 2008 in Dallas, Texas (USA).

I have been member of the Scientific Committee of 41st European Physical Society Conference on Plasma Physics held in Belfast in 2017

Author and coauthor of 68 papers published in peer-reviewed journal.

Awards and prizes

F.  Auriemma, D. Lopez-Bruna, R.  Lorenzini, B. Momo, I. Predebon, Y. Suzuki, A. López-Fraguas, Y. Narushima, F. Sattin, D. Terranova ‘A novel approach to studying transport in plasmas with magnetic islands’ Nuclear Fusion 58, 096037 (2018)

C.F. Maggi, H.Weisen, J.C. Hillesheim, A. Chankin, E. Delabie, L. Horvath, F. Auriemma, I.S. Carvalho, G. Corrigan, J. Flanagan, L. Garzotti, D. Keeling, D. King, E. Lerche, R. Lorenzini et al  ‘Isotope effects on L-H threshold and confinement in tokamak plasmas,’ Plasma Physics and Controlled Fusion 60,125002(2018)

R. Lorenzini, F. Auriemma, A. Fassina, E. Martines, D. Terranova and F. Sattin, ‘Internal Transport Barrier Broadening through Subdominant Mode Stabilization in Reversed Field Pinch Plasmas’, Physical Review Letters  116, 185002 (2016)

R. Lorenzini, E. Martines, P. Piovesan, D. Terranova, P. Zanca, M. Zuin et al.’Self-organized helical equilibria as a new paradigm for ohmically heated fusion plasmas’, Nature Physics, 5, 570 (2009)

R. Lorenzini, D. Terranova, A. Alfier, P. Innocente, E. Martines, R. Pasqualotto, P. Zanca,'Single-Helical-Axis States in Reversed-Field-Pinch Plasmas', Physical Review Letters 101, 025005 (2008)

 

Fiorella Lo Schiavo
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STEM area: Biomedical sciences and biotechnology

Competences: cellular biology, genetics

Keywords: arabidopsis, plant senecence, plant somatic embryogenesis

Region: Veneto


Position/Role

Full Professor of Plant Physiology, University of Padua, Faculty of Science, Dept. of Biology, Padova.

Professional career

July 1974 Doctorate in Biology cum laude, University of Naples; October 1974 winner of a national competition for a doctorate fellowship at Normale Superiore, Pisa; 1975-1976 one year fellowship c/o Laboratory of Molecular Biology, Universidad Autonoma de Madrid (Prof. A. Garcia-Bellido); 1976 short EMBO fellowship Inst. of Botany, University of Nottingham (Prof. E. Cocking); 1976 Research Fellow Institute of Mutagenesis and Differentiation National Research Council, Pisa (Prof. M. Terzi); 1983-1984 Research Associate, dept. of Genetics and Plant Pathology, University of California at Berkeley (Prof. Z.R. Sung); 1986 Research Fellow, International Institute of Genetics and Biophysics, Naples; 1987-1990 Associate Professor of Plant Physiology, University of Basilicata, Faculty of Agriculture at Potenza; 1991-2000 Associate Professor of Plant Physiology, University of Padua, Faculty of Science at Padova.

Scientific results

The research activity of Prof. Lo Schiavo began with her thesis (in the field of bacterial molecular genetics at the International Institute of Genetics and Biophysics) which received special mention at the competition for the best doctoral thesis in Molecular Biology (Scoffone-Cremona prize). Subsequently she worked in Drosophila genetics (Canto Blanco University, Madrid, Spain) and plant somatic cell genetics (Pisa, Italy). In 1982 she entered in a project for the isolation and characterization of temperature-sensitive carrot cell mutants: the study of alterations in plant cell differentiation has been the object of two consecutive 3-year programmes of the European Union, that originated several publications, the core of her scientific production up to the end of the 90's. After that, she studied the action mechanism of auxin, its perception and its effects on signal transduction. Later on, she has been involved in the isolation and physiological characterization of potassium ionic channels and the definition of their functions during various plant developmental stages. Another subject presently investigated concerns the basic mechanisms of organ senescence using cell cultures as model systems and, in particular, the PCD as the final stage of cell senescence. Recently, she is investigating the role of signalling molecules as calcium and ROS induced by abiotic stresses in model plants and in a crop as rice.

 

In all these years she has been responsible of National and International research projects, has acted as scientific referee for the European Union, the National Science Foundation of USA and various journals. She is past general Secretary of the IAPTC (International Association Plant Tissue Culture). She has been a director of the Italian Society of Plant Physiology from 1995 to 2002 and from 2009 to 2014 a director of the Italian Society of Plant Biology. She has been a member of the School of Doctorate in Bioscience and Biotechnology of the University of Padova, acting as coordinator of the curriculum “Biotechnology”. Since the beginning of 2014, she is a member of the new School of Doctorate in Bioscience, acting as a coordinator of the curriculum  “Biochemistry & Biotechnology “. She is the National Representative of the FESPB since September 2012.

Editorial work and publications

She is author of more than one hundred scientific papers.

Formentin E., Sudiro C., Perin G., Riccadonna S., Barizza E., Baldoni E., Lavezzo E., Stevanato P., Sacchi G.A., Morosinotto T., Zottini M., Lo Schiavo F. (2018)  Transcriptome and cell physiological analyses in different rice cultivars provide novel insights into adaptive and salinity stress responses, Frontiers in Plant Science,  vol. 9,  p.204, DOI: 10.3389/fpls.2018.00204.

 

Teardo E, Carraretto L, Wagner S, Formentin E, Behera S, De Bortoli S, Larosa V, Fuchhs P, Lo Schiavo F, Raffaello A, Rizzuto R, Costa A, Schwarzländer M and Ildiko Szabò (2017) Physiological characterization of a plant mitochondrial calcium uniporter in vitro and in in vivo. PLANT PHYSIOLOGY vol. 173 p. 1-16  www.plantphysiol.org/cgi/ DOI: 10.1104/pp.16.01359

Teardo E, Carraretto L, De Bortolis S, Costa A, Behera S, Wagner R, Lo Schiavo F, Formentin E, Szabo I (2015) Alternative splicing-mediated targeting of the Arabidopsis Glutamate Receptor 3.5 to mitochondria organelle morphology. PLANT PHYSIOLOGY vol. n.167 n.1 p. 216-227

 

Cristina Ruberti, Alex Costa, Emanuela Pedrazzini, Fiorella Lo Schiavo, Michela Zottini (2014). FISSION1A, an Arabidopsis tail-anchored protein, is localized to three subcellular compartments. Molecular Plant 7, p. 1393–1396,  doi: 10.1 093/mp/ssu027. doi : 10.1093/mp/ssu027

L—

Marco Vescovi, Michael Riefler, Micael Gessuti, Ondrej Novak, Thomas Schmulling, Fiorella Lo Schiavo (2012). Programmed cell death induced by high levels of cytokinin in Arabidopsis cultured cells is mediated by the cytokinin receptor CRE1/AHK4 . JOURNAL OF EXPERIMENTAL BOTANY, vol. 63, p. 2825-2832

 

Awards and prizes

Special mention at the competition for the best doctoral thesis in Molecular Biology (Scoffone-Cremona prize) 1974.

Daniela Lucangeli
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STEM area: Psychology and neurosciences

Competences: developmental psychology, educational psychology

Keywords: brain plasticity, children, development, developmental disorders, dyscalculia, intelectual giftedness, learned helplessness, learning, learning disabilities, mathematics, neuroscience, numbers, psychopatology of learning, special educational needs, teaching strategies, teenagers

Region: Veneto


Position/Role

Vice Rector of the Orientation and Tutorship for the University of Padua and Full Professor of Developmental Psychology at the same university

Professional career

After graduating in Philosophy in 1988 and in Psychology in 1991 at the University of Padua, in 1997 she continued her education with a PhD on an international project in Developmental Psychology at the University of Leiden, in the Netherlands. Her career continued within the university: in 1998 she was a researcher in Developmental Psychology, in 2001 an associate professor and in 2005 a full professor of Developmental Psychology still at the University of Padua. Since 2007 she has been the director of the same university with a delegation to the Orientation and Tutorship, a role she still covers today.

 

Scientific results

Daniela Lucangeli’s main research interests concern the development and strengthening of numerical intelligence, the maturational processes in the developmental age (first and second childhood, school age and adolescence) and the learning mechanisms in typical and atypical development. She is also involved in the study of functions (language, memory, attention, emotions, metacognition, self-regulation), learning disabilities (such as dyslexia, dysorthography, dysgraphia, dyscalculia) and special educational needs. She also carries out research and studies on enhancing learning, behavioral and cognitive deficits, giftedness and high potential profiles, learning emotions and learned impotence. She has been promoting for years, with the group of researchers and scientists of the World Academy of Sciences for Learning Difficulties, a strong movement of actions for the decline of scientific research in the practices of prevention, strengthening and rehabilitation of development disharmonies. In fact, scientific research has shown that through early intervention in the different "labors" of development, it is possible to obtain the optimization of processes even in situations of possible disability (language, learning, cognitive development, etc.). The focus of her work is not only that related to the analysis of cognitive profiles and to the possible diagnosis but above all to use the best aid strategies for maximum brain plasticity. In recent times she has devoted herself to the study of circuit networks related to warm cognition and emotional learning circuits. In particular, studies aimed at highlighting the contribution of hereditary factors and cultural factors in the development of psychological processes and education. She deepens the study of cognitive functions and processes with the aim of highlighting the important implications of neuroscience in educational processes. As Director, with responsibility for tutoring, "in itinere" and "incoming" guidance from the University of Padua, she coordinates the implementation of regional and European projects aimed at guiding young people in the choice of university and professional.

Editorial work and publications

Daniela Lucangeli is editor of the journal “Difficoltà In Matematica” (Erickson) and referee for several specialized magazines. She is the author of numerous national and international publications and scientific and educational essays, including (in the last five years):

(2017) Sella F, Berteletti I, Lucangeli D, Zorzi M. Pre-school children use space, rather then counting, to infer the numerical magnitude of digits: evidence for a spatial mapping principle. Cognition, 158, 56-67. 

(2016) Sella F, Berteletti I, Lucangeli D, Zorzi M. Spontaneous non‐verbal counting in toddlers. Developmental Science, 19(2), 329-337. 

(2016) Benavides-Varela S, Butterworth B, Burgio F, Arcara G, Lucangeli D, Semenza C. Numerical Activities and Information Learned at Home Link to the Exact Numeracy Skills in 5–6 Years-Old Children. Frontiers in psychology, 7. 

(2015) Sella F, Berteletti I, Lucangeli D, Zorzi M. Varieties of quantity estimation in children. Developmental Psychology, 51(6), 758. 

(2014) Caviola S, Mammarella IC, Lucangeli D, Cornoldi C. Working memory and domain-specific precursors predicting the success in learning written subtraction problems. Learning and Individual Differences, 36, 92-100. 

(2014) Re AM, Pedron M, Tressoldi PE, Lucangeli D. Response to Specific Training for Students With Different Levels of Mathematical Difficulties. Exceptional Children, 80(3), 337-352. 

(2013) Al-Yagon M, Cavendish W, Cornoldi C, Fawcett AJ, Grunke M, Hung, LY, Jimenez JE, Karande S, van Kraayenoord CE, Lucangeli D, Margalit M, Montague M, Sholapurwala R. The Proposed Changes For DSM-5 for SLD and ADHD: International Perspectives-Australia, Germany, Greece, India, Israel, Italy, Spain, Taiwan, United Kingdom, and United States. Journal of Learning Disabilities, 46, 58-72.

(2013) Colomer C, Miranda A, Re AM, Lucangeli D. Numerical and Calculation Abilities in Children with ADHD. Learning Disabilities: A Contemporary Journal, 11(2), 1-15.  

(2013) Mammarella IC, Bomba M, Caviola S, Broggi F, Neri F. Lucangeli D, Nacinovich R. Mathematical difficulties in nonverbal learning disability or co-morbid dyscalculia and dyslexia. Developmental neuropsychology, 38(6), 418-432. 

(2013) Mammarella IC, Caviola S, Cornoldi C, Lucangeli D. Mental additions and verbal-domain interference in children with Developmental Dyscalculia (DD). Research in Developmental Disabilities, 34(9), 2845-2855.

 

Awards and prizes

 

Daniela Lucangeli is President of the Association for the National Coordination of Specialized Teachers (CNIS) and member of the Scientific Committees of numerous national and international research associations such as the Italian Association for Research and Intervention in Learning Psychopathology (AIRIPA) and the Italian Association of Psychology (AIP Development Section). Vice President for the International Development of the International Academy for Research in Learning Disabilities (IARLD). Technical member of the National Observatory for Childhood and Adolescence. Scientific component of the Technical Commission appointed by the Ministry of Education for guidelines on specific learning disorders (DSA), Bes (Special Educational Needs). And he is a member of the National Commission of the CNOP (National Council of Psychologists) "Wellness at School". Vice President of the Research Foundation HPNR (Human Potential Network Research). Scientific Director of the Learning Center (28 Centers in Italy). Scientific Director of the Gate Italy Association (Gifted and Talent Education). Scientific Manager of the Regional Research Center and Educational Services for Learning Difficulties.

Adriana Maggi
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STEM area: Biomedical sciences and biotechnology

Competences: cellular pharmacology, pharmacological biotechnologies

Keywords: aging, drugs, estrogen receptors, gender pharmacology, hepatic metabolim, menopause, metabolic diseases, neuroinflammation

Region: Lombardy


Position/Role

Coordinator of the Center of Excellence for Neurodegenerative Diseases at the University of Milan

 

Professional career

After graduating in Biological Sciences at the University of Milan in 1973, she continued her scientific interests with a scholarship at the Institute of Pharmacology and Pharmacognosy directed by Professor Rodolfo Paoletti. Winner of the Salk Institute - University of Texas Award, she continued her education initially at the Department of Pharmacology and Neurobiology of the University of Texas, in Houston, in the United States and then at the Department of Cell Biology of the Baylor College of Medicine under the guidance of Professor Bert O'Malley. Back to Italy in 1982 as a researcher, she founded and directed a University-Industry model collaboration center, the result of an initiative by the University of Milan and the Hoffman-LaRoche Pharmaceutical Company: the Milan Molecular Pharmacology Lab (MPL). At the end of the 1980s, as an associate professor, she continued her research at the Department of Pharmacological Sciences of the University of Milan. Since 2002 she has directed the Center of Excellence on Neurodegenerative Diseases of the University of Milan, an experimental center financed by a fund organized by the Ministry of University and Research in which she is directly responsible for a research group made up of 20 researchers and young graduates. From 2006 to 2014 she founded and presided over the TOP srl, a spin-off of the University of Milan. As an expert in Pharmaceutical Biotechnology she holds various ministerial positions: she is a member of the Advisory Committee of the Italian Prime Minister in the field of Biotechnology, Biosafety and Life Sciences, of the Scientific Committee "Innovative Medicine Initiative" of the European Union, of the European ESFRI Working Group for Health and Food, of the Council of the European Society for Molecular Imaging (ESMI) and delegate of the MIUR for the European Pilot Initiative on Joint Programming on Neurodegenerative Diseases of which she is Vice-President since 2010. She is currently nominated by the American Society of Endocrinology member of the Endocrine Society EU Task force for Endocrine Disrupters and collaborates with the Innovative Medicine Initiative2 as a member of the SSG Panel on Neurodegeneration.

Scientific results

The research carried out by Adriana Maggi has always focused on the study of the physiological activity performed by estrogens, with particular reference to non-reproductive organs. Initial studies are associated with the discovery that the estrogen receptor is present in all brain cells (oligodendrocytes, astrocytes, microglia and neurons), even in brain areas not associated with reproductive functions, but linked to the control of emotional activities (frontal cortex, hippocampus). More recently, the study of the anti-inflammatory activity of estrogens active in microglia has led to new hypotheses about the higher incidence of neurodegenerative diseases in female subjects and the role of sex in the response to different stimuli and ischemic insults. In order to better understand the action of estrogens, Adriana Maggi designed and created a unique model for the study of the action of these hormones in living organisms and for the identification of new drugs active through these receptors: the ERE reporter mouse Luc. This reporter system was subsequently used to generate other model systems for the study of other receptors (for example the PPAR receptor) and complex processes such as oxidative stress, inflammation, calcium transport, apoptosis and others. The availability of the ERE-Luc model for the study of estrogen receptor activity has shown for the first time that estrogen is very active in the liver in mammals. Recent studies show that in female organisms estrogens control hepatic metabolism and lipid synthesis in close relationship with reproductive activity. This action is fundamental in differentiating energy metabolism in mammals of the two sexes and the discovery made has significant significance not only for a better understanding of sex-dependent hepatic metabolism, but also for understanding the etiopathogenetic mechanisms of a series of diseases associated with aging and, in women, closely related to post-menopause.
The results of the research carried out have opened up a new way of understanding the metabolic differences between males and females, allowing the understanding of gender / gender differences in the prevalence of a very wide range of diseases that include most of the diseases associated with aging (from diabetes to neurodegenerative diseases) and in the hepatic metabolism of drugs and xenobiotics in general. Furthermore, the discovery of the relevance of estrogen activity in the liver suggests a new way to generate more effective postmenopausal hormone replacement formulas with fewer side effects.
The research activity of Adriana Maggi has been recognized and supported by numerous national and international funding bodies. On funding from the European Commission, the professor coordinated 4 European research consortia for the study of the physiology and aging of women and endocrine disruptors, and more recently her research was funded by the Nationals Institutes of Health with a RO1 grant for the study of the aging of women and ERC for the study of gender physiology.

 

 

Editorial work and publications

She is the author of more thab 200 scientific publications, 6 patents and 3 monographs- Among the most recent publications:

 

(2017) Della Torre S, Maggi A.Sex Differences: A Resultant of an Evolutionary Pressure? Cell Metabolism, 25:499-505.

(2017) Rizzi N, Rebecchi M, Levandis G, Ciana P and Maggi A. Identification of novel loci for the generation of reporter mice. Nucleic Acids Reserach, 45:e37.

(2016) Della Torre S, Mitro N, Fontana R, Gomaraschi M, Favari E, Recordati C, Lolli F, Quagliarini F, Meda C, Ohlsson C, Crestani M, Uhlenhaut NH, Calabresi L, Maggi A. An Essential Role for Liver ERα in Coupling Hepatic Metabolism to the Reproductive Cycle. Cell Reports, 15:360-71.

(2016) Villa A, Vegeto E, Poletti A, Maggi A.Estrogens, Neuroinflammation, and Neurodegeneration. Endocrine Reviews. 37:372-402.

Benedusi V, Martini E, Kallikourdis M, Villa A, Meda C and Maggi A. Ovariectomy shortens the life span of female mice. Oncotarget  (2015) 6:10801-11.

(2014) Della Torre S, Benedusi V, Fontana R, Maggi A, Energy Metabolism and reproduction, an ancestral balance to be preserved for women health. Nature Review Endocrinology, 10:13-23.

(2012) Villa A, Della Torre S, Stell A, Cook J, Brown M, Maggi A. Tetradian oscillation of estrogen receptor α is necessary to prevent liver lipid deposition. Proceedings of the National Academy of Sciences USA. 109:11806-11.

(2011) Della Torre S, Rando G, Meda C, Stell A, Chambon P, Krust A, Ibarra C, Magni P, Ciana P. and Maggi A. Amino Acid-dependent activation of liver Estrogen Receptor alpha integrates metabolic and reproductive functions via IGF-1. Cell Metabolism, 13: 205-214.

(2010) Rando G, Horner D, Biserni A, Ramachandran B, Caruso D, Ciana P, Komm B. and Maggi A. An innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals. Molecular Endocrinology, 24: 735-744.

(2009) Brufani M, Ceccacci F, Filocamo L, Garofalo B, Joudioux R, La Bella A, Leonelli F, Migneco LM, Bettolo RM, Farina PM, Ashcroft GS, Routley C, Hardman M, Meda C, Rando G, Maggi A. Novel locally active estrogens accelerate cutaneous wound healing. A preliminary study. Molecular Pharmaceutics, 6: 543-56.

(2003) Ciana P, Raviscioni M, Mussi P, Vegeto E, Que I, Parker MG, Lowik C and Maggi A. In vivo imaging of transcriptionally active estrogen receptors. Nature Medicine, 9: 82-6.

 

Awards and prizes

Adriana Maggi won many awards and recognitions during her professional career, including the Salk-Institute-University of Texas Award; the NATO Award for exchange studies, the Lecture Award of the British Endocrine Society, the Farmindustria-Telethon Research Award, the PFIZER Investigator-Initiated Research Award, the ERC Advanced Grant Award.

 

 

 

Natalia Malara
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STEM area: Biomedical sciences and biotechnology

Competences: cancer research, molecular medicine, oncology, translational medicine

Keywords: biosensors, cancer stem cells, circulating endothelial cells, circulating molecular biomarkers, circulating tumour cells, liquid biopsies, tissue regeneration

Region: Calabria


Position/Role

Senior researcher Bionem (Bio- and Nano-Engineering for Medicine) nanotechnology laboratories Experimental and Clinical Medicine Department, Magna Graecia, University of Catanzaro.

Professional career

Graduated from the University of Messina in Medicine and Surgery, she continued her studies at the Catholic University of the Sacred Heart in Rome, where she specialized in Medical Oncology. After getting her PhD in Cell and Human Biology at the University of Messina, as winner of the two-year AIRC scholarship, she has carried out her research as contract professor at the Magna Graecia University of Catanzaro. She has collaborated with the Italian Institute of Technology (IIT) of Genoa in the post-doc position, for the development of devices aimed at characterizingprognostic biomarkers in cancer patients. NM in 2005 worked as consultant for the Consulate of the Italian Embassy in Nosy-Be, Madagascar, for evaluating oncological risks linked to territorial problems, especially in paediatric age. In the project "Monitoring and early diagnosis of tumours linked to exposure to environmental toxic substances in the Calabrian population", in 2009, she worked as consultor for ARPACAL - Regional Agency for Environmental Protection of Calabria. In 2011 she was a scientific consultant for the project "Centro del Farmaco" IRCS San Raffaele Pisana in Rome. 

Since 2013 she has been appointed Scientific Director of the CHARACTEX research project (Characterization of circulating tumour cells from peripheral, medullary and cord blood, and tissue tumour cells by cytometric flow evaluation and in vitro expansion). She takes part into the national project as scientific coordinator and coordinator of the Germaneto section, Magna Graecia University, for the SCENIC project (immunophenotypic characterization of circulating endothelial cells from peripheral, medullary and cord blood by cytometric flow evaluation in standardized instrumental, reagents and protocol conditions) commissioned by Becton Dickinson (BD). In 2015 she was the scientific director of the ENDOFIRE research project, (immunophenotypic characterization of circulating endothelial cells and peripheral blood exosomes by cytometric flow evaluation in patients with atrial fibrillation) and of the observational study ENXOCORE, (immunophenotypic characterization of circulating differentiated (CEC) and progenitor endothelial cells (EPC) and peripheral blood exosomes, by cytofluorimetric evaluation, in patients with acute myocardial infarction without ST segment elevation (NSTEMI). Since 1999 she has been member of the Italian Association of Medical Oncologists (AIOM) and from 2017 she has been Member of the Royal Society of Medicine. 

In 2017 she qualified as associate professor in the scientific disciplinary sectors MED06 (Medical Oncology) and MED46 (Translational Medicine) For the academic year 2017-18 she has been director and didactic coordinator of the Post-graduate Course inScreening, diagnosis,  prognosis and efficacy assessment of in vitro drugs using liquid biopsy" at the Faculty of Medicine and Surgery, University Magna Graecia. For the academic year 2018-19 she is director and didactic coordinator of the 1st level Master in "Liquid Biopsy in Tumours and other Complex Diseases". At BionemL@b laboratory, Department of Experimental and Clinical Medicine, Magna Graecia University, she works on designing and creating devices or lab-on-chips aimed at isolating and characterizing circulating tumour cells.

Scientific results

Natalia Malara has helped to develop a neoadjuvant protocol for membrane immunomodulation in patients with lung cancer to increase the anti-tumor immune reaction (degree thesis awarded with "Fondazione Bonino-Pulejo Award") and to characterize the impact of paraphysiological mechanisms linked to aging in breast cancer biology (with particular interest on alterations of cell cycle control proteins) (2004). Furthermore, she has developed innovative protocols to isolate and characterize the subset of non-haematological cells found in the blood, aimed at defining the identity of biological marker and establishing the degree of biological conformity to the pathology. In particular, she has developed a standardized protocol for the isolation and culture of circulating tumour cells for their cytofluorimetric, morpho-immunocytochemical and genetic-mutational characterization (2018). NM has helped standardizing the normal values range ​​of different biomarkers such as circulating endothelial cells, and assessing their prognostic impact in tumour and cardiovascular pathology (2018). Author of books on  oncology (2009, 2019) and holder of national and international patents (2018), NM has developed, in the field of personalized medicine, a test that investigates the in vitro sensitivity of cancer stem cells, isolated from tissue biopsies (removal of tumour tissue) and from liquid biopsies (peripheral blood sampling), to chemotherapeutic agents (2007, 2014, 2016). She developed a protocol to isolate and expand in vitro human stem cells from different sources (adult tissues and embryonic appendages) to be used in tissue regeneration (2015). She participates and collaborates in the creation of devices with nanoscale architectures (2014) for the separation and detection of biological species for applicative purposes in clinical field, with particular interest in their use in the field of personalized preventive medicine (2018).

Editorial work and publications

Natalia Malara is author of more than 80 scientific publications, including:

[2004] Malara N, A Leotta, A Sidoti, S Lio, R D'Angelo, B Caparello, F Munao, F Pino, A Amato. Ageing, hormonal behaviour and cyclin D1 in ductal breast carcinomas. The Breast; 15(1):81-9.

[2018] Malara N, Gentile F, Coppedè N, Coluccio ML, Candeloro P, Perozziello G, Ferrara L, Giannetto M, Careri M… et al.  Superhydrophobic Lab-on-chip exploring protonation state in secretome assess personalized onset-risk of sporadic tumour. Nature Precision Oncology 2:26/2018.

[2018] Lanuti P, Simeone P, Rotta G, Almici C, Avvisati G, Azzaro R, Bologna G, Budillon A, Di Cerbo M, …Malara N …et al. Standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges. Sci Rep. Apr 11;8(1):5823. 

[2009] Malara N. “Il Tessuto Tumorale”, editore Eurolink, distributore Feltrinelli 

[2019] Gandolfo G, Temperilli F, Amoroso A. “La Medicina di Laboratorio nell’emergenza”, seconda edizione, Malara N. capitolo “Emergenze in Oncologia” e capitolo “Recenti applicazioni cliniche della citofluorimetria a flusso, in rapido sviluppo: le cellule tumorali circolanti, le cellule endoteliali circolanti, le cellule staminali circolanti” Delfino editore, Roma.

[2018]Malara N.  Method and kit for diagnosis and/or prognosis of non-haematological tumours. PCT/IB2018/051438 Brevetto Internazionale

[2007]Malara N. Test di valutazione di efficacia dei chemioterapici effettuato su tre distinte e complementari popolazioni cellulari derivate dalla massa tumorale solida.CZ2007A000004Brevetto Nazionale

[2014]Malara N, Givigliano F, Trunzo V, Macrina L, Raso C, Amodio N, Aprigliano S, Minniti A M, Russo… et al.  In vitro expansion of tumour cells derived from blood and tumour tissue is useful toredefine personalized treatment in non-small cell lung cancer patients.Journal of biological regulators and homeostatic agents 28(4):717-31.

[2016]Malara N, Trunzo V, Foresta U, Amodio N, De Vitis S, Roveda L, Fava M, Coluccio ML, Macrì R…et al. Ex-vivo characterization of circulating colon cancer cells distinguished in stem and differentiated subset provides useful biomarker for personalized metastatic risk assessment. Journal of Translational Medicine 14(1) 12/2016.

[2016]Malara N, Guzzi G, Mignogna, C, Trunzo V, Camastra C, Della Torre A, Di Vito A, Lavecchia A M… et al.  Non-invasive real-time biopsy of intracranial lesions using short time expanded circulating tumor cells on glass slide: Report of two cases.BMC Neurology 16(1) 12/2016

[2015]Malara N, Musolino G, Trunzo V, Minniti AM, Cristodoro L, Polistina M, Renzulli A, Mollace V. Novel application of mesenchymal stem cells from mammary artery. International Journal of Cardiology 182C:466-468 01/2015. 

[2014] Malara N,Coluccio ML, Limongi T, Asande M,  Trunzo V, Cojoc G, Raso C, Candeloro P, Perozziello  G….et al. Folic Acid Functionalized Surface Highlights 5-Methylcytosine-Genomic Content within Circulating Tumor Cells.Small 07/2014; 10(21). 

Awards and prizes

Of the 84 publications produced by NM only some have been chosen amonng national and international patents, books and chapters of books and scientific articles that allow to briefly review the results achieved in itinere.

[2004] Malara N, A Leotta, A Sidoti, S Lio, R D'Angelo, B Caparello, F Munao, F Pino, A Amato. Ageing, hormonal behaviour and cyclin D1 in ductal breast carcinomas. The Breast; 15(1):81-9.

[2018] Malara N, Gentile F, Coppedè N, Coluccio ML, Candeloro P, Perozziello G, Ferrara L, Giannetto M, Careri M… et al.  Superhydrophobic Lab-on-chip exploring protonation state in secretome assess personalized onset-risk of sporadic tumour. Nature Precision Oncology 2:26/2018 

[2018] Lanuti P, Simeone P, Rotta G, Almici C, Avvisati G, Azzaro R, Bologna G, Budillon A, Di Cerbo M, …Malara N …et al. Standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges. Sci Rep. Apr 11;8(1):5823. 

[2009] Malara N. “Il Tessuto Tumorale”, editore Eurolink, distributore Feltrinelli 

[2019] Gandolfo G, Temperilli F, Amoroso A. “La Medicina di Laboratorio nell’emergenza”, seconda edizione, Malara N. capitolo “Emergenze in Oncologia” e capitolo “Recenti applicazioni cliniche della citofluorimetria a flusso, in rapido sviluppo: le cellule tumorali circolanti, le cellule endoteliali circolanti, le cellule staminali circolanti” Delfino editore, Roma. 

[2018] Malara N. Method and kit for diagnosis and / or prognosis of non-haematological tumors. PCT / IB2018 / 051438 International patent

[2007] Malara N. Test of evaluation of efficacy of chemotherapeutic drugs performed on three distinct and complementary cell populations derived from the solid tumor mass. CZ2007A000004 National patent

[2014] Malara N, Givigliano F, Trunzo V, Macrina L, Raso C, Amodio N, Aprigliano S, Minniti A M, Russo… et al.  In vitro expansion of tumour cells derived from blood and tumour tissue is useful to redefine personalized treatment in non-small cell lung cancer patients. Journal of biological regulators and homeostatic agents 28(4):717-31.

[2016] Malara N, Trunzo V, Foresta U, Amodio N, De Vitis S, Roveda L, Fava M, Coluccio ML, Macrì R…et al.  Ex-vivo characterization of circulating colon cancer cells distinguished in stem and differentiated subset provides useful biomarker for personalized metastatic risk assessment. Journal of Translational Medicine 14(1) 12/2016.

[2016] Malara N, Guzzi G, Mignogna, C, Trunzo V, Camastra C, Della Torre A, Di Vito A, Lavecchia A M… et al.  Non-invasive real-time biopsy of intracranial lesions using short time expanded circulating tumor cells on glass slide: Report of two cases. BMC Neurology 16(1) 12/2016

[2015] Malara N, Musolino G, Trunzo V, Minniti AM, Cristodoro L, Polistina M, Renzulli A, Mollace V. Novel application of mesenchymal stem cells from mammary artery. International Journal of Cardiology 182C:466-468 01/2015. 

[2014] Malara N, Coluccio ML, Limongi T, Asande M,  Trunzo V, Cojoc G, Raso C, Candeloro P, Perozziello G….et al. Folic Acid Functionalized Surface Highlights 5-Methylcytosine-Genomic Content within Circulating Tumor Cells. Small 07/2014; 10(21). 

Francesca Mallamaci
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STEM area: Clinical sciences and nutrition science

Competences: nephrology

Keywords: arterial hypertension, cardiovascular complications of renal failure, dyalisis, epidemiology of kidney diseases, kidney transplant, molecular genetics of arterial hypertension, molecular genetics of kidney diseases, progressive kidney diseases, renal failure

Region: Calabria


Position/Role

Chief of the Nephrology, Dialysis and Transplantation Department of the "Bianchi-Melacrino-Morelli" Hospital in Reggio Calabria

Professional career

She graduated in Medicine at the University of Messina in 1978 and she became a Nephrology Specialist in 1983 at the same University.  She spent 2 years (1981-1982) as a Clinical Scientist at the Renal and Transplantation Unit of the Western Infirmary in  Glasgow (Scotland).

She has attended several Courses in Hypertension, Clinical Epidemiology and Molecular Genetics at the  Erasmus University in  Rotterdam (The Netherland).  In addition, she has attended many other international and High Quality Nephrology Courses. Since 2001, she is recognised by the European Society of Hypertension as a Hypertension Specialist.

Scientific results

Her fields of interest are Hypertension, CV complications in renal patients including dialysis patients, renal disease progression, Epidemiology of Renal disease and molecular genetics of renal diseases and Hypertension.  

She is involved in many national and international research studies such as "Lung Water by Ultra-Sound (US) guided treatment to prevent death and cardiovascular complications in high-risk end stage renal disease patients with cardiomyopathy (LUST STUDY)". The aim of this study is to create a database with clinical tests performed in very high-risk dialysis patients in order to investigate the impact of volume expansion  which is a well-known CV and renal risk factor.

The LUST Study is a randomized clinical trial aimed at testing whether the application of chest US may reduce mortality, heart failure,  myocardial  infarction,  progression  of  cardiac  disease  and  hospitalizations  in  dialysis  patients  with myocardial ischemia (a history of myocardial infarction with or without ST elevation or unstable angina, acute coronary  syndrome  documented  by  ECG  recordings  and cardiac  troponins  or  stable  angina  pectoris  with documented coronary artery disease by prior coronary angiography or ECG) and/or stage III-IV NYHA heart failure over a 2 years follow-up.

Francesca Mallamaci is Chairwoman of the ERA-EDTA working Group EURECA-m. She has contributed to building up a large registry of European dialysis patients in order to identify and validate traditional and non-traditional CV risk factors.

Editorial work and publications

Associate Editor/Team Editor of NDT since January 2013.

Past Editor-in-Chief of the Journal of Nephrology (December 2006 to January 2013).

She is author of a vast number of scientific papers published in national, and mainly international, high impact journals. Among them the most recent are:

(2019) Mallamaci F, Tripepi G, D'Arrigo G, Borrelli S, Garofalo C, Stanzione G, Provenzano M, De Nicola L, Conte G, Minutolo R, Zoccali C. Blood Pressure Variability, Mortality, and Cardiovascular Outcomes in Chronic Kidney Disease Patients. Clin J Am Soc Nephrol. 2019 Jan 2. [Epub ahead of print]

(2018) Mallamaci F, Tripepi R, D'Arrigo G, Porto G, Versace MC, Marino C, Sanguedolce MC, Testa A, Tripepi G, Zoccali C. Long-term blood pressure monitoring by office and 24-h ambulatory blood pressure in renal transplant patients: a longitudinal study. Nephrol Dial Transplant. 2018 Nov 23. [Epub ahead of print]

(2018) Mallamaci F, D'Arrigo G, Tripepi R, Leonardis D, Porto G, Testa A, Abd ElHafeez S, Mafrica A, Versace MC, Provenzano PF, Tripepi G, Mancini P, Zoccali C. Office, standardized and 24-h ambulatory blood pressure and renal function loss in renal transplant patients. J Hypertens. 2018 Jan;36(1):119-125.

(2017) Mallamaci F, Tripepi G. [Pulmonary congestion and hypertension in hemodialysis patients]. G Ital Nefrol. 2017 Mar;34(Suppl 69):36-40.

(2016) Mallamaci F. Highlights of the 2015 ERA-EDTA congress: chronic kidney disease, hypertension. Nephrol Dial Transplant. 2016 Jul;31(7):1044-6.

(2016) Mallamaci F, Torino C, Tripepi G. Physical exercise in haemodialysis patients: time to start. Nephrol Dial Transplant. 2016 Aug;31(8):1196-8.

(2016) Mallamaci F, Tripepi R, Leonardis D, Mafrica A, Versace MC, Provenzano F, Tripepi G, Zoccali C. Nocturnal Hypertension and Altered Night-Day BP Profile and Atherosclerosis in Renal Transplant Patients. Transplantation. 2016 Oct;100(10):2211-8.

(2015) Mallamaci F, Testa A, Leonardis D, Tripepi R, Pisano A, Spoto B, Sanguedolce MC, Parlongo RM, Tripepi G, Zoccali C. A genetic marker of uric acid level, carotid atherosclerosis, and arterial stiffness: a family-based study.American Journal of Kidney Diseases, 65(2):294-302.

(2015) Mallamaci F, Tripepi R, Leonardis D, Mafrica A, Versace MC, Provenzano F, Tripepi G, Zoccali C. Nocturnal Hypertension and Altered Night-Day BP Profile and Atherosclerosis in Renal Transplant Patients. Transplantation, 100(10):2211-8.

Awards and prizes

At least 15 abstracts written by Prof. Mallamaci were awarded at national and international conferences such as the European Renal Association (ERA-EDTA) and the Congress of the American Society of Nephrology.

Prof. Mallamaci, in her main fields of interest such as chronic renal failure, is at the 19th position in an international ranking created and periodically updated by the University of Baltimore (EXPERTSCAPE- http://expertscape.com/ex/chronic+kidney+disease). Furthermore, in this ranking, prof Mallamaci is second in a gender based analysis.

Irene Mammarella
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STEM area: Psychology and neurosciences

Competences: clinical developmental psychology, developmental neuropsychology

Keywords: autism, learning disabilities, math anxiety, non-verbal disorder

Region: Veneto


Position/Role

Associate professor of Developmental Psychology, University of Padova

Professional career

She graduated in Psychology in 2002 at the University of Padova and obtained the PhD in 2006. During her PhD she spent periods as visiting scholar at the Hospital for Sick Children (Toronto, Canada), and at the University of Gent (Belgium). In 2008 she became a Lecturer (assistant professor) in developmental psychology at the University of Padova. She has been a visiting researcher at the Universitè Catholique de Louvain-la-Neuve (Belgium) in 2013, at Liverpool John Moores University (UK) in 2017, and at the Goldsmith University of London (UK) in 2018. In 2013 she co-founded a university clinical centre specialized in diagnosis and intervention of children with neurodevelopmental disorders (Lab.D.A). Since 2017 she is the clinical supervisor of a new centre (Lab.D.A. Nord). She established and directed since 2014 a post-graduate course in Developmental disorders and psychopathologies to train specialized practitioners (University of Padova).

Scientific results

Since the beginning of her research career, she has examined the Nonverbal learning disability, a neurodevelopmental disorder characterized by low visuospatial skills and good verbal abilities. She became a leading researcher on this topic, publishing several research on peer review journals. Due to these, in 2017, she has been invited from the Columbia University, (Institute of Psychiatry, New York, USA) to be part of the international committee, aimed to include the Nonverbal learning disability in the Diagnostic and Statistical Manual (DSM 5). Her current research projects focus on studying differences and similarities of the Nonverbal learning disability and other neurodevelopmental disorders, such as ADHD and Autism spectrum disorder.

Other research interests also involve the analysis of cognitive processes (such as visuospatial working memory) in relation to academic achievement, specifically mathematics. Recently, she collaborated with the University of Cambridge (UK) in studying the development of mathematics anxiety and its relation with maths performance.

Overall, her applied scientific results, other than have been published on international peer review journals have been developed in standardized tests and intervention materials with specialized publishers.

 

Editorial work and publications

Irene C. Mammarella is Academic Editor of PlosOne and is in the Editorial board of international scientific journals, such as Educational Psychology, Learning and Individual Differences e Journal of Experimental Child Psychology.

She is author of many international publications, here are listed some of them:

[2018] Cardillo, R., Menazza, C. & Mammarella, I. C. Visuoconstructive Abilities and Visuospatial Memory in Autism Spectrum Disorder Without Intellectual Disability: Is the Role of Local Bias Specific to the Cognitive Domain Tested? Neuropsychology, 32, 822-834. doi: 10.1037/neu0000472

 

[2018] Mammarella, I. C., Donolato, E., Caviola, S., & Giofrè, D. Anxiety profiles and protective factors: A latent profile analysis.Personality & Individual Differences, 124, 201-208. doi: 10.1016/j.paid.2017.12.017

 

[2018] Mammarella, I. C., Caviola, S., Giofrè, D. & Szücs, D. The underlying structure of visuospatial working memory in children with mathematical learning disability.British Journal of Developmental Psychology, 36, 220-235 doi: 10.1111/bjdp.12202

 

[2017] Mammarella, I. C., Caviola, S., Giofrè, D., & Borella, E. Separating math from anxiety: The role of inhibitory mechanisms.Applied Neuropsychology: Child, doi: 10.1080/21622965.2017.1341836

 

[2016] Hill, F., Mammarella, I. C., Devine, A., Caviola, S., Passolunghi, M. C. & Szücs, D. Maths anxiety in primary and secondary school students: Gender differences, developmental changes and anxiety specificity.Learning and Individual Differences, 48, 45-53.

 

[2016] Mammarella, I. C., Ghisi, M., Bomba, M., Bottesi, G., Caviola, S., Broggi, F. & Nacinovich, R. Anxiety and depression in children with Nonverbal learning disabilities, reading disabilities, or typical development.Journal of Learning Disabilities, 49, 130-139.

 

[2015] Mammarella, I. C., Hill, F., Devine, A., Caviola, S., & Szücs, D. Math anxiety and developmental dyscalculia: A study on working memory processes.Journal of Clinical and Experimental Neuropsychology, 37, 878-887.

 

[2014] Mammarella, I. C., & Cornoldi, C. An analysis of the criteria used to diagnose children with Non-verbal learning disabilities (NLD).Child Neuropsychology, 20, 255-280. 

[2014] Mammarella, I. C., Giofrè, D., Caviola, S., Cornoldi, C., & Hamilton, C. Visuospatial working memory in children with Autism: The effect of semantic global organization. Research in Developmental Disabilities, 35, 1349-1356.

[2013] Mammarella, I. C., Bomba, M., Caviola, S., Broggi, F., Neri, F., Lucangeli, D., & Nacinovich, R. Mathematical difficulties in nonverbal learning disability or co-morbid dyscalculia and dyslexia.Developmental Neuropsychology, 38, 418-432.

[2013] Mammarella, I. C., Borella, E., Pastore, M., & Pazzaglia, F. The structure of visuospatial memory in adulthood.Learning and Individual Differences, 25, 99-110.

 

Awards and prizes

Irene C. Mammarella is member of several international associations: APS (Association for Psychological Science), MCLS (Mathematical Cognition and Learning Society), EARLI (European Association for Research on Learning and Instruction), IARLD (International Academy for Research in Learning Disabilities).

She is member of the Directive board of the Italian association for learning disorders (Airipa) and member of the Italian psychological association (AIP), developmental and education.

Since 2017 is member of the panel for updating the national guidelines of Specific learning disorders, organized by the Italian Association of Dyslexia (AID).

Recently, in 2018, she co-founded the Italian association of the Nonverbal learning disability (AIDNV) and the international Society for research on learning disorders (SRLD).

Giulia Manca
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STEM area: Physics

Competences: nuclear physics, particle physics

Keywords: high energy physics, particle physics, quarkonia

Region: Sardinia


Position/Role

Associate professor at the University of Cagliari and at the National Institute of Nuclear Physics.

Professional career

After graduating in Physics at the University of Cagliari in 1999, she completed her training with a PhD in Physics at Oxford University which she obtained in 2003. In the same year she continued her studies with a post-doc in England again, first at Oxford and then at the University of Liverpool. From 2000 to 2006, she worked as a Scientific Associate with the Fermilab laboratory in Chicago, in the United States. In 2007, she returned to Italy, to Cagliari, as a researcher at the INFN (National Institute of Nuclear Physics) and, the following year, at the University. From 2012 to 2013 she collaborated with the CERN laboratory in Geneva. In 2015 she won an ERC Consolidator Grant with the CNRS (Center National de la Recherche Scientifique) and moved to Orsay, Paris, until the end of 2016. In 2016 she was also visiting professor at the University of Cambridge, UK. In 2017 she became associate professor at the University of Cagliari. She is currently involved in the study of heavy ion physics with the LHCb experiment at CERN and leads a research team of six post-docs, two students and two researchers divided between Orsay and Cagliari.

Scientific results

In 2002, together with her colleagues from the CDF experiment (Collider Detector at Fermilab) she observed the decay of the W and Z bosons (fundamental particles of the Standard Model) into electrons and measured the production cross section and the ratio for the first time to that energy, publishing the work in her PhD thesis. In 2003 she worked with a group of 14 people dedicated to the research of chargino and neutralino supersymmetric particles in their leptonic decay, coming to coordinate them and publishing the best world limit at that time on their mass and production cross section. In 2007 she became a member of the LHCb (Large Hadron Collider beauty) collaboration – the LHC accelerator experiment of the CERN, that aims to measure the parameters of the CP-violation and decays and rare phenomena related to hadrons in which the beauty quark can (b quark) can be found - at CERN in Geneva. She participated in several studies on the production of associated states of quark-antiquark (quarkonia) by publishing several works on the subject and collaborating with expert theorists of the field. From 2009 to 2013 she became the person responsible for that physics in the experiment. In 2015 she founded a new research group within LHCb opening the way to precision measurements of Quark Gluon Plasma at high speed, her current field of research.

Editorial work and publications

She is author of numerous national and international publications, including:

2017) Aaij R, Manca G et al. [LHCb Collaboration]. Study of prompt D0 meson production in pPb collisions at=5 TeV, Journal of High Energy Physics, 1710, 090.

(2014) Manca G. Review on quarkonia production at LHC, International Journal of Modern Physics A, 29, 1430014.

(2013) Aaij R, Manca G et al. [LHCb Collaboration]. Production of J/ and¡mesons inpp collisions at=8 TeV, Journal of High Energy Physics, 1306, 064.

(2013)A.A. Alves Jr., G. Manca et al. [LHCb Muon Collaboration]. Performance of the LHCb muon system, Journal of Instrumentation, 8, P02022.

(2012) Aaij R, Manca G et al. [LHCb Collaboration]. Measurement of¡production inpp collisions at=7 TeV, European Physical Journal C, 72, 2025.

(2011) Aaij R, Manca G et al. [LHCb Collaboration] Measurement of J/ production inpp collisions at=7 TeV. European Physical Journal C, 71, 1645.

(2010) Anelli M, Manca G et al. [LHCb Muon Collaboration]. Performance of the LHCb muon system with cosmic rays, Journal of Instrumentation ,5, P10003.

(2007) Aaltonen T, Manca G et al. [CDF Collaboration]. Search for chargino-neutralino production in pp collisions at=1.96 TeV,  Phys. Rev. Lett. 99 191806.

(2008) Aaltonen T, Manca G et al. [CDF Collaboration]. Search for supersymmetry in pp collisions at=1.96 TeV Using the tri-lepton signature of Chargino-Neutralino production, Physical Review Letters, 101, 251801.

(2005) D. Acosta, G. Manca et al. [CDF Collaboration]. First measurements of inclusive W and Z cross-sections from Run II of the Tevatron collider, Physical Review Letters, 94, 091803.

(2007) Abulencia A, Manca G et al. [CDF Collaboration]. Measurements of inclusive W and Z cross-sections in pp collisions at=1.96 TeV,Journal of Physicc G, 34,2457.

She is a reviewer of the journals Journal of High Energy Physics and European Physical Journal.

Awards and prizes

In 2005 she won the Particle Physics and Astronomy Research Council fellowship for two years. In 2015 she gained a 5 years ERC Consolidator Grant for a total of 1.9 million euros. Since 2016 she is part of the AcademyNet network.
She is on the list of Top Italian Scientists since 2012.

 

Claudia Manzi
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STEM area: Psychology and neurosciences

Competences: social psychology

Keywords: ethnicity, family, identity, prejudice, religion, transition, violence

Region: Lombardy


Position/Role

Associate Professor of Social Psychology at the Università Cattolica in Milan

Professional career

After graduating in Philosophy with a specialization in Human Sciences at the Università Cattolica of Milan in 1999, she continued her education at the same university with a PhD in Social and Developmental Psychology, during which she collaborated in research and training activities of the University Center for Studies and Research on the Family. From 2003 to 2005 she was a research fellow in Social Psychology at the Department of Psychology of the Università Cattolica of Milan. From the following year until 2016 she was a researcher in Social Psychology at the Faculty of Education of the Università Cattolica. In 2008 she was a visiting professor at the University of Tennessee, in the Child and Family Studies department and in 2016 she held the same position in the department of Psychology at the University of Sussex. In 2009 she was selected as a consultant at the Research Methods and Data Analysis office of the United Nations (UN), Office of Internal Oversight Services (New York). Since 2016 she is associate professor of Social Psychology at the Faculty of Education of the Università Cattolica of Milan.

Scientific results

Claudia Manzi studies identity construction and development processes, in particular identity motivations, adult identity, identity related to transition, ethnic prejudice, family differentiation, cross-cultural psychology. She collaborated on these issues with the Universidad de los Andes, Bogotá, in Colombia, in 2007, for a study on identity changes in transition periods, and in the same year with the Center for the Study of Youth and Political Violence, 'University of Tennessee, where she participated in the final phase of data analysis and publication of the results of a project coordinated by the World Health Organization's Program for Child and Adolescent Health and Development. Since 2008 she has participated in the international research team for the cross-cultural research project "Motivated identity construction in cultural context" funded by the Economic and Social Research Council (ESRC). Finally, since 2014 she is a member of the international research team "World Relationship Study", funded by the Japan Society for the Promotion of Science.

 

Editorial work and publications

Since 2011 Claudia Manzi is a member of the Editorial Board of the Encyclopaedia of Quality of Life Research (Ed. A. Michalos), Springer of New York and referee of international journals of excellence as Journal of Personality, Journal of Marriage and Family, Journal of Adolescence, Journal of Early Adolescence, Self and Identity, Psychology of Individual Differences, Social Psychology.

She is the author of numerous national and international publications including:

 

(2017) Manzi C, Roccato M, Paderi F, Vitrotti S, Russo S. The social development of right-wing authoritarianism: The interaction between parental autonomy support and societal threat to safety. Personality and Individual Differences, 109: 1-4.

 

(2015) Manzi C, Roccato M, Russo S. What buffers right-wing authoritarian responses to threat? An experimental study to test the moderation of meaning. Personality and Individual Differences, 83:117-121.

 

(2015) Manzi C, Parise M, Iafrate R, Sedikides C, Vignoles VL. In so far as you can be part of me: The influence of intrusive parenting on young adult couple identity. Self & Identity, 14: 5, 570-582.

 

(2014) Manzi C, Brambilla M. Identity change. In A. Michalos (Eds.). Encyclopedia of Quality of Life Research, Dordrecht, Netherlands, Springer, 2167-2168.

 

(2014) Manzi C, Ferrari L, Rosnati R, Benet-Martinez V. Bicultural Identity Integration of Transracial Adolescent Adoptees: Antecedents and Outcomes. Journal of Cross Cultural Psychology, 45(6):888-904.

 

(2013) Brambilla M, Manzi C, Regalia C, Verkuyten M. Religiosity and Prejudice: Different Patterns for Two Types of Religious Internalization. The Journal of Social Psychology, 153:486-498.

 

(2011) Scabini E, Manzi C. Family Processes and Identity. In S. J. Schwartz, K. Luyckx, and V. L. Vignoles (Eds), Handbook of Identity Theory and Research, New York: Springer, 565-584.

 

(2010) Manzi C. Identità adulta nella letteratura psicosociale. In E. Marta, C. Regalia (Eds.), Identità in relazione. Le sfide odierne dell'essere adulto. Milano: The McGraw-Hill Companies, 17-31.

 

(2010) Manzi C, Vignoles V, Regalia C. Accommodating a new identity: Possible selves, identity change, and well-being across two life-transitions. European Journal of Social Psychology, 40:970-984. 

(2006) Manzi C, Vignoles V, Regalia C, Scabini E. Cohesion and enmeshment revisited: Family differentiation, identity, and psychological well-being in two European cultures. Journal of Marriage and the Family, 68: 673-689.

 

Awards and prizes

Since 2007 Claudia Manzi has been a member of the European Association of Social Psychology, since 2009 of the Society for Personality and Social Psychology and since 2014 of the Italian Association of Psychology, section of Social Psychology.

 

Lucia Margheriti
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STEM area: Natural and environmental sciences

Competences: seismology, structure of the interior of the Earth

Keywords: earthquakes, local amplification effects, magnitude, seismic anisotropy, seismic series

Region: Lazio


Position/Role

Senior researcher at the National Institute of Geophysics and Volcanology (Istituto Nazionale di Geofisica e Vulcanologia, INGV), National Earthquake Centre; Responsible for data analysis for seismic surveillance and monitoring

Professional career

After graduating in Geology at the University of Rome La Sapienza in 1991, she continued her studies through a specialization scholarship (1992-1993) in Seismology at the United States Geological Survey in Menlo Park, CA, USA. In 1994 she continued her specialization at the University of L'Aquila, Department of Physics and then at the National Institute of Geophysics (ING) of Rome, which in 2000 became the National Institute of Geophysics and Volcanology (INGV). She developed her skill as researcher at INGV first on a temporary position, and then on a permanent position. In 2003 she became senior researcher and started coordinating projects and researchers’ groups.

Since 1998 she participated to the seismic surveillance, first as a seismologist in charge of the ipocentral locations, with the target of alerting the Civil Protection, a service interrupted during the maternity periods in 2000 and 2002; then, in 2015, she qualified also as a tsunami alert operator and finally, today, she works in the shifts as responsible of the communication to the Civil Protection Department (DPC).

From 2007 to 2014 she coordinated a research group consisting of 25 researchers studying geodynamics and the structure of the interior of the Earth. Between 2009 and 2013 she was the coordinator of the mobile seismic network of the National Earthquake Center and she was involved in the organization of earthquake emergency response activities. Since 2014 she is responsible for a group (about 25 persons) of technicians and researchers working on data analysis for surveillance and seismic monitoring.

She coordinated important national and international projects involving Italian, European and US institutions and universities such as the RETREAT project (2002-2007), the Messina 1908-2008 project (2007-2009), the INGV-DPC Test project sites for detailed multidisciplinary monitoring (2007-2009), the AlpArray project (2015-2018). She is responsible for some of the activities that INGV carries out for the DPC and of the agreement between INGV and the Civil Protection Agency of the Lazio Region. She always participated in the INGV outreach activities with the schools, the public and the media.

Scientific results

Her scientific interests have focused in recent years, on the analysis of seismic sequences for the characterization of active fault systems and for understanding the possible variation of the earth's Crust physical parameters during the occurrence of the sequences themselves. For 15 years, she has been dealing with the analysis of shear wave splitting to define the seismic anisotropy and the state of deformation of the Crust and of the Earth's Mantle. This analysis allows to characterize the crustal fracture field and to define its relations with the active stress field and with the presence of fluids. The characterization of the seismic anisotropy, when done on waves that travel in the Earth's Mantle, allows us instead to formulate geodynamic models on a regional scale: the subduction zone of the southern Tyrrhenian Sea, where the Ionic plate deeps below the Calabrian arc, was the first region of the Earth's mantle where was observed a toroidal flow of the mantle at the edges of the subducting plate (Civello and Margheriti 2004).

During the years of her training she studied site effects: how the seismic waves are amplified and modified by the surface geology especially when there are incoherent deposits, irregular topographical conformation of the area interested by seismic shaking. In 1993, she was among the pioneers in using the recordings of environmental vibrations (seismic noise) to characterize the response of sites that had recorded the 1989 San Francisco earthquake.

 

Editorial work and publications

She is the author of about 70 international scientific publications, including:

 

(2016) Baccheschi P, Pastori M, Margheriti L, Piccinini D. Shear wave splitting of the 2009 L'Aquila seismic sequence: fluid saturated microcracks and crustal fractures in the Abruzzi region (Central Apennines, Italy). Geophysical Journal International, 204 (3): 1531-1549.doi: 10.1093/gji/ggv536

(2014) Margheriti L, Lucente FP, Park J, Pondrelli S, Levin V, Steckler MS, Baccheschi P, Salimbeni S. Large-scale coherent anisotropy of upper mantle beneath the Italian peninsula comparing quasi-Love waves and SKS splitting. Journal of Geodynamics, DOI: 10.1016/j.jog.2014.07.007

(2014) Govoni A, Marchetti A, De Gori P, Di Bona M, Pio Lucente F, Improta L, Chiarabba C, Nardi A, Margheriti L, Piana Agostinetti N, Di Giovambattista R, Latorre D, Anselmi M, Ciaccio MG, Moretti M, Castellano C, Piccinini D. The 2012 Emilia seismic sequence (Northern Italy): Imaging the thrust fault system by accurate aftershocks location Tectonophysics. http://dx.doi.org/10.1016/j.tecto.2014.02.013

(2013) Salimbeni S, Pondrelli S, Margheriti L. (2013). Hints on the deformation penetration induced by subductions and collision processes: Seismic anisotropy beneath the Adria region (Central Mediterranean).Journal of Geophysical Research: Solid Earth, DOI: 10.1002/2013JB010253

(2011) Baccheschi P, Margheriti L, Steckler M S & Boschi E. Anisotropy patterns in the subducting lithosphere and in the mantle wedge: A case study—The southern Italy subduction system. Journal of Geophysical Research, 116, B08306.

(2010) Lucente FP, Gori PD, Margheriti L, Piccinini D, Bona MD, Chiarabba C, Agostinetti NP. Temporal variation of seismic velocity and anisotropy before the 2009 MW 6.3 L'Aquila earthquake. Italy: Geology, 38:1015–1018, doi: 10.1130/G31463.1.

(2004) Civello S and Margheriti L. Toroidal mantle flow around the Calabrian slab (Italy) from SKS splitting, Geophysical Reserach Letters, 31, L10601, doi:10.1029/2004GL019607.

(2000) Margheriti L, Azzara MR, Cocco M, Delladio A and Nardi A. Analysis of borehole broad-band recordings: Test sute in the Po basin, Northern Italy. Bulletin of the Seismological Society of America, 90, 6:1454-1463.

(1996) Margheriti L, Nostro C, Cocco M and Amato A. Seismic anisotropy beneath the northern Apennines (Italy) and its tectonic implications. Geophysical Reserach Letters, 23; 20:2721-2724.

(1994) Margheriti L, Boatwright J, Wennerberg L. A comparison of Coda and S-wave spectral ratios as estimates of site response in the Southern San Francisco Bay area. Bulletin of the Seismological Society of America, 84, 6:1815-1830.

 

Daniela Mari
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STEM area: Clinical sciences and nutrition science

Competences: geriatrics

Keywords: cardiovascular risk, centenarians, degenerative diseases, dna, elders, genes, longevity, longevity genetic bases

Region: Lombardy


Position/Role

Head of U.O.C. of Geriatrics of the IRCCS Foundation Ca ’Granda Maggiore Hospital of the Policlinico of Milan

 

Professional career

After obtaining a degree in Medicine and Surgery, at the University of Milan, from 1976 she continued her training as a researcher in Internal Medicine until 1991. From 2007 to 2010 she directed the experimental research laboratory on aging of the IRCCS Istituto Auxologico Italian and University of Milan and of the Department of Medical and Rehabilitative Sciences with Geriatric-Cardio-Vascular specialization of the IRCCS Istituto Auxologico Italiano. Until 2014 she was responsible for the School of Specialization in Geriatrics, and for the Master's Degree in Rehabilitation Sciences of the Health Professions. Since 2010 she has directed the U.O.C. (complex operative unit) of Geriatrics of the IRCCS Foundation Ca ’Granda Ospedale Maggiore Policlinico of Milan in agreement with the University of Milan. Daniela Mari is also an associate professor of Geriatrics at the University of Milan, at the Department of Clinical and Community Sciences. Responsible U.O.C. of Geriatrics of the IRCCS Foundation Ca ’Granda Maggiore Hospital of the Policlinico of Milan.

Scientific results

Daniela Mari has been leading the Milan research group that studies cardiovascular risk factors and their genetic variants in longevity and centenarians, and neurodegenerative diseases in the elderly for many years. During the period spent as head of the experimental research laboratory on aging of the Italian Auxological Institute of Milan, Daniela Mari and colleagues focus on the study of the genetic bases of longevity, investigating the characteristics of a large number of seventy-year-old children of centenarians. To this end they also resort to DNA methylation analysis, or to an epigenetic modification of DNA, a process which consists in the binding of a methyl group (a carbon atom bound to three hydrogen atoms) to a nitrogenous base. They also investigate the dose-effectiveness relationship of oral anticoagulant therapy (TAO) in the elderly, genetic and non-genetic risk factors in cerebrovascular diseases and the influence of obesity and metabolic status on aging and age-related diseases.

 

Editorial work and publications

Daniela Mari is Associate Editor in the Editorial Board of the Journal of Gerontology & Geriatrics (JGG).

She is also the author of numerous national and international scientific publications, including:

 

(2016) Esposito S, Mari D, Bergamaschini L, et al. Pneumococcal colonization in older adults. Immunity & Ageing, 13(1).

(2016) Abbate C, Trimarchi PD, Rotondo E, Mari D, et al. Spontaneous confabulations in amnestic-mild cognitive impairment due to Alzheimer’s disease: a new (yet old) atypical variant?. Neurocase.

(2016) Muscogiuri D, Mari D, et al. 25 Hydroxyvitamin D Deficiency and Its Relationship to Autoimmune Thyroid Disease in the Elderly. International Journal of Environmental Research and Public Health, 13(9):850.

(2016) Abbate C, Caputo L, Damanti S, Mari D, et al. Reversible Parkinson's Dementia Associated with Withdrawal of Androgen-Deprivation Therapy for Prostate Cancer. Journal of the American Geriatrics Society.

(2016) Arosio B, Casati M, Gussago C, Mari D, et al. Adenosine Type A2A Receptor in Peripheral Cell from Patients with Alzheimer’s Disease, Vascular Dementia, and Idiopathic Normal Pressure Hydrocephalus: A New/Old Potential Target. Journal of Alzheimer's disease, 54(2):1-9.

(2016) Ogliari G, Smit RAJ, van der Spoel E, Mari D, et al. Thyroid Status and Mortality Risk in Older Adults With Normal Thyrotropin: Sex Differences in the Milan Geriatrics 75+ Cohort Study. The Journals of Gerontology Series A Biological Sciences and Medical Sciences.

(2016) Dionigi Rossi P, Bilotta C, Consonni D, Mari D, et al. Predictors of clinical events occurring during hospital stay among elderly patients admitted to medical wards in Italy. European Journal of Internal Medicine, 32.

(2016) Gussago C, Arosio B, Guerini F, Mari D, et al. Impact of vitamin D receptor polymorphisms in centenarians. Endocrine.

(2016) Oldoni E, Fumagalli GG, Serpente M, Mari D, et al. PRNP P39L Variant is a Rare Cause of Frontotemporal Dementia in Italian Population. Journal of Alzheimer's disease: JAD, 50(2).

(2015) Hovath S, Pirazzini C, Bacalini MG, Mari D, et al. Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring. Aging, 7(12).

 

Awards and prizes

Daniela Mari obtained a grant from the MIUR, the Ministry of Health and the Lombardy Region for studies on haemostasis, the genetics of aging and longevity. Since 2010  she has been a member of the Regional table for the appropriateness in Medicine and of the "Fundamental Group" Regional Technical Table of the Directorate General for Health of the Lombardy Region. In 2012 she received the position of "Scientific Expert" of the French Agence Nationale de la Recherche for the review of research projects. Since 2013 she has been member of the register of auditors for the evaluation of ministerial programs and research products (ANVUR), since the same year she is part of the European Commission's Action-Group A3 “European Innovation Partnership on Active and Healthy Aging: Action For Prevention Of Functional Decline And Frailty ”. Daniela Mari is also a partner in the European study: MID- FRAIL Study FP7-Health 2011.

 

 

 

 

 

 

 

 

 

 

 

 

 

Luisa Donatella Marini
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STEM area: Mathematics

Competences: mathematics for scientific computing

Keywords: elasticity, electromagnetism, finite elements, fluid dynamics, numerical methods for partial differential equations, plate bending, semiconductor devices, virtual elements

Region: Lombardy


Position/Role

Full Professor of Numerical Analysis at the University of Pavia

Professional career

After graduating in Mathematics at the University of Pavia in 1970 she has been fellow first, and then Researcher of C.N.R. at the Istituto di Analisi Numerica in Pavia (now IMATI-CNR) from 1973 to 1990.  Since 1990 she is Full Professor of Numerical Analysis, at the Faculty of Science of the University of Genova until 1993, and then at the Engineering Faculty of the University of Pavia.

Scientific results

The field of interest of Luisa Donatella Marini is, generally speaking, the analysis of numerical schemes for the solution of elliptic partial differential equations (of second and fourth order) by means of different kinds of finite element methods: conforming, non-conforming, hybrid, mixed, and equilibrium. More specifically, she applied finite element techniques for the treatment of problems coming from various applications: semiconductor device simulation, electromagnetism, fluid-dynamics, structural mechanics. Particular emphasis was given to the approximation of non-coercive problems, which lead to develop various techniques for stabilizing Galerkin formulations, for applications to domain decomposition methods with non-matching grids, and to advection dominated problems. In the last decade she was particularly interested in developing and analyzing schemes based on Discontinuous Galerkin methods, for the discretization of various applied problems, such as Darcy flows, advection-diffusion problems, and Reissner-Mindlin model for plate problems. The more recent production is devoted to a new technique, the Virtual Element Method, for the discretization of Pde's  with applications.

 

Editorial work and publications

L. Donatella Marini serves or has served as Associate Editor of various journals:  SISC (SIAM Journal on Scientific and Statistical Computing) from 1988 to 1993,  CMAME (Computer Methods in Applied Mechanics and Engineering) since 2001,  IMA Journal of Numerical Analysis, since 2017, the Italian Journal of Pure and Applied Mathematics since 2008, and is member of the Advisory Board of CAMES (Computer Assisted Methods in Engineering and Sciences) since 2014.  She is also reviewer for other numerous important international journals, and evaluator for national and international proposals.

She authored over 100 publications on international journals. Several of her journal articles are among the most cited in mathematics. Below five selected publications. For a complete list I refer to my webpage: http://arturo.imati.cnr.it/marini

[2002] Unified analysis of Discontinuous Galerkin Methods for Elliptic Problems. SIAM Journal on Numerical Analysis, 39(5):1749-1779 (with Arnold DN, Brezzi F, Cockburn B). 

[1985] Marini LD. Two families of mixed finite elements for second order elliptic problems. Journal of Numerical Mathematics, 47:217-235 (with Brezzi F, Douglas J jr.,).

[2013] Basic principles of Virtual Element Methods. Mathematical Models and Methods in Applied Sciences, 23(1):199-214 (with Beirão da Veiga L, Brezzi F, Cangiani A, Manzini G, Russo A.). 

[2013]Virtual Elements for linear elasticity problems, SIAM J. Numer. Anal. 51(2):794-812 (with  Beirão da Veiga L, Brezzi F).

[2014] The Hitchhiker's Guide to the Virtual Element Method, Math. Models Methods. Appl. Sci. 24(8):1541-1573 (with Beirão da Veiga L, Brezzi F, Russo A).

Awards and prizes

She was awarded the Turner-Kirk Distinguished Visiting Fellowship for the GCS programme at the Isaac Newton Institute (Cambridge, UK), July-December 2019, is Member of the scientific committee of the 20th International Conference on Finite Elements in Flow Problems (FEF 2019, Chicago), is representative of SIMAI (The Italian Society of Applied and Industrial Mathematics) in the General Assembly and Managing Board of the European Community on Computational Methods in Applied Sciences (ECCOMAS) since 2014,  has been Chair of the committee for the ICIAM (The International Council for Industrial and Applied Mathematics)  Collatz prize in 2015. In 2010 she was elected a member of the European Academy of Science (EURASC), where she also serves as a member of the scientific committee of the Division of Mathematics (March 2018-March 2021). She has been member of the Committee for PhD programs at the University of Pavia from 1999 to 2009, and then Director of the Doctoral School of  “Scienze e Tecnologie A. Volta” of the University of Pavia from 2009 to 2013. In 2012 she delivered the inaugural lecture for the opening of the academic year at the University of Pavia.

Maria Marsella
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STEM area: Natural and environmental sciences

Competences: geodesy, geology, geomatics, volcanology

Keywords: hydrogeological risk, natural risks, territory, volcanology

Region: Lazio


Position/Role

Associate Professor of Geodesy and Geomatics in the degree courses in Civil Engineering, Safety and Civil Protection and Aerospace at the University of Rome La Sapienza. CEO of SurveyLAb srl.

Professional career

After graduating in Physics in 1987 with a thesis on the LAGEOS satellite mission for the study of Earth’s crust movements in the Mediterranean Area, she continued her education with a PhD in Geodetic and Topographical Sciences at the University of Bologna, discussing a thesis on Spatial Geodesy Techniques (SLR and GPS) applied to the Study of Deformations. In 1992 she became a researcher at the University of Rome “La Sapienza”. From 2003 to 2005 she was Visiting Scientist at the USGS in Reston (Virginia), where she worked on projects for the integration of GPS/INS data for the georeferencing of data acquired through aerial surveys. Since 2001 she is associate professor at the Faculty of Civil and Industrial Engineering of the University of Rome “La Sapienza” (qualified as Ordinary since 2012). During her academic career she taught Higher Education courses on Image Analysis Remote Sensing Techniques and GIS and on Aerial survey techniques for natural disasters and was a member of the Teaching Board of the PhD in Geoinformation of the University of Tor Vergata. She currently participates in the PhD in Infrastructure and Transport Engineering of Sapienza University.

In 2008 she founded the spin-off of Sapienza Survey Lab dedicated to the development of innovative systems for the control of the territory and civil infrastructures using in situ sensors and satellite observations (GNSS and DInSAR). He is currently CEO of Survey Lab.

Scientific results

Maria Marsella's main activity is research on geodetic and geomatic techniques for land monitoring and civil infrastructure protection. She is an expert in the acquisition and processing of earth observation data with optical and SAR sensors and spatial geodesy data.She carried out studies and research for the development of interpretative and forecasting models in areas subject to hydrogeological risk and in active volcanic areas, basing on the integration of aerial and satellite remote sensing data with in situ measurements.She coordinated numerous research projects funded by national bodies such as the MIUR, the Italian Space Agency, the Civil Protection Department of the National Institute of Geophysics and Volcanology, and European projects under the EU programs FP7 and H2020.

 

Editorial work and publications

She is author of more than one hundred publications, including:

(2016) Scifoni S, Bonano M, Marsella M, Sonnessa A, Tagliafierro V, Manunta M. On the joint exploitation of long-term DInSAR time series and geological information for the investigation of ground settlements in the town of Roma (Italy). Remote Sensing of Environment, 182:113-127 3.

(2015) Palenzuela JA, Marsella M, Nardinocchi C, Pérez JL, Fernández T. Landslide detection and inventory by integrating LiDAR data in a GIS environment. Landslides, 12(6):1035-1050,9.

(2015) Marsella M, D’Aranno PJV, Scifoni S, Sonnessa A, Corsetti M. Terrestrial laser scanning survey in support of unstable slopes analysis: the case of Vulcano Island (Italy). Natural Hazards, 78(1):443-459,5.

(2012) Marsella M, Baldi P, Coltelli M, Fabris M.The morphological evolution of the Sciara del Fuoco since 1868: reconstructing the effusive activity at Stromboli volcano. Bulletin of Volcanology, 74,1:231-248.

(2009) Proietti C, Coltelli M, Marsella M, Fujita E. A quantitative approach for evaluating lava flow simulation reliability: LavaSIM code applied to the 2001 Etna eruption. Geochemistry Geophysics Geosystems,10,9.

(2008) Manunta M, Marsella M, Zeni G, Sciotti M, Atzori S, Lanari R. Two-scale surface deformation analysis using the SBAS-DInSAR technique: a case study of the city of Rome Italy.International Journal of Remote Sensing, 29,6:1665-1684.

(2008) Baldi P, Coltelli M, Fabris M, Marsella M, Tommasi P. High precision photogrammetry for monitoring the evolution of the NW flank of Stromboli volcano during and after the 2002-2003 eruption. Bulletin of Volcanology, 70,6:703-715.

(2007) Vicari A, Herault A, Del Negro C, Coltelli M, Marsella M, Proietti C. Modeling of the 2001 lava flow at Etna volcano by a cellular automata approach. Environmental Modelling & Software, 22,10:1465-1471.

(2005) Baldi P, Fabris M, Marsella M, Monticelli R. Monitoring the morphological evolution of the Sciara del Fuoco during the 2002 - 2003 Stromboli eruption using multi-temporal photogrammetry. ISPRS, Journal of Photogrammetry and Remote Sensing, 59,4:199-211.

(2002) Baldi P, Bonvalot S, Briole P, Coltelli M, Gwinner K, Marsella M, Puglisi G, Remy D. Validation and comparison of different techniques for the derivation of digital elevation models and volcanic monitoring (Vulcano Island Italy). International Journal of Remote Sensing, 23,22:4783-4800.

 

Awards and prizes

In 2017 she was called to join the Scientific Technical Committee for the Government Commissioner for the rebuilding in the territories affected by the 24 August 2016 earthquake at the Presidency of the Council of Ministers. In March 2016 Survey Lab, of which she was CEO, won the H2020 SME Instrument-Phase II-Space Call with the IMODI project (Monitoring by using satellites the stability of buildings and infrastructure). From 2011 to 2014 she was an expert for the Research Quality Assessment (VQR-ANVUR). Between 2002 and 2013 she was an expert evaluator of projects for the Aeronautics and Space Call of the European Commission's FP6 and FP7 framework programmes for technological development. In 2002 and 2003 and again in 2017 she collaborated with the National Civil Protection Department for the management of the Stromboli Emergencies 2002-03 and 2017. She is a member of the Management Board of the Aerospace Research Center of Sapienza (CRAS).

 

Mirella Mastretti
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STEM area: Computer science

Competences: artificial intelligence, computer technology, cybernetic physics, electronics, mathematical modeling, network engineering

Keywords: big data, cybernetics, innovation, management, nanotechnologies, SMEs, strategy, women

Region: Lombardy


Position/Role

Member of the Board of Directors of "Azienda Farmacie Comunali" of Cornaredo (Milano) 

Mathematics and computer science professor 

Founding partner and vice-President of an association to support female entrepreneurship (SMEs and startups) 

Innovation ambassadress

Professional career


 After the graduation in computer science, under the guidance of Prof. Giovanni degli Antoni, she continues her studies with a specialization in cybernetics / artificial intelligence and electronic systems engineering. Since 1989 she has been a researcher at the Central Research Laboratory of an important and innovative Italian telecommunications company. Then she started her contribution to some international standardization committees, in particular the one related to the VHDL language. Since 1993 she has been manager of R&D projects on areas related to logical synthesis automation tools, using expert systems, neural networks, fuzzy logic and project coordinator, in an international context, for the research and application of video encoding and decoding algorithms. Since 2000 she has been responsible for Multimedia Content Delivery projects and Network Architectures. In 2013 he coordinated activities related to telemedicine and energy saving for the smart city in collaboration with Monzino and Milano Ricerche Cardiology Center. In 2014 she won a public selection for titles for a Collaboration with the University of Milan at the Department of Pharmacological and Biomolecular Sciences. In 2013 she founded, with a group of colleagues, an association of women (Talent4Rise, which, under her direction, would become a founding member of the Triulza Foundation, civil society pavillon for EXPO2015). The aim is to provide visibility to female STEM talents. She held the position of Chairwoman and member of the General Council of the Triulza Foundation until 2016. Next she was appointed Chairwoman Emerita and Vice President and, during the same period, she was appointed as Strategic Marketing Director for an ICT company. Since 2014 she has been a member of the Board of Directors of an in-house company of a municipality in the Milan hinterland that groups together local pharmacies.
 

Scientific results

For about 30 years Mirella Mastretti has been dealing with innovative areas both as a researcher and a teacher of advanced training, and as manager in academia, civil society and ICT companies contexts. Her activities involved the coordination of funded projects at national and international level. Member of international scientific and standardization committees, she contributed to the VHDL language definition, to original logical synthesis tools (patented) implementation and to innovative algorithms for audio/video, AI (Artificial Intelligence) applications and neural networks. 

She always managed projects and opportunities to liven up the debate on innovation in health and life-science, the role of science and technology in the society, with particular focus on methods, tools and technologies, to ensure a good quality of life and assistance for chronic or elderly people and for inclusive training; all this has been carried out in a context of "sharing economy" that sees the collaboration between companies, the academic world and the third sector

Editorial work and publications

Some papers
 [1990] Antoniazzi S., Mastretti M. An Interactive Environment for Hardware/Software System Design at the Specification Level. Microprocessing and Microprogramming, vol. 30.
 [1991] Antoniazzi S., Mastretti M. An Architectural Design Support Environment for High- Performance Digital Systems. Microprocessing and Microprogramming, vol.32.
 [1995] Mastretti M., Sturlesi M. Tomasello S. Static Analysis of VHDL Code: Simulation Efficiency and Complexity. Proceedings VHDL: Champions of the Second Generation, San Diego, California.
 [1996] Mastretti M., Sturlesi M., Tomasello S. Quality Measures and Analysis: A Way to improve VHDL Models, Hardware Component Modeling. Kluwer Academic Publisher.
 [1998] Mastretti M., Paolillo E., Di Bello P., Mercandalli D. Technologies for the Information Society, Developments and Opportunities, IOS Press.
 [1999] Boscolo M., Mastretti M., Paolillo E. Technology as the Catalyst of Users' Acceptance in Electronic Commerce. Flexible Working, New Network Technologies, pp. 121-132.
 Books
 [1996] M. Mastretti, Current Issues in Electronic Modeling. Kluwer Academic Publisher
 
[2015] M. Mastretti, Best Practices for EXPO2015: Tecniche Nuove 
 
[2016] M. Mastretti, Impresa che funziona - come finanziare ricerca e innovazione con i fondi pubblici -  Sandit.
 
 

Awards and prizes

"Milano Ricerche" Award 1989 -  Lombardy Region Project Award (SURE - SMAU Milano 2012) -  Milan Chamber of Commerce Award (Rise2Up 2014) -  Appointment to "digital champion", ambassadress of innovation, by Riccardo Luna, on behalf of the Italian Prime Minister (2015) - Appointment of President Emeritus of T4R (2016) 

Barbara Mazzolai
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STEM area: Engineering

Competences: biorobotics, robotic engineering

Keywords: bio-inspired engineering, robot

Region: Tuscany


Position/Role

Coordinator of the Micro-BioRobotics Center (CMBR) in Pontedera, at the Italian Institute of Technology (IIT) of Genoa, and Vice Director with responsibility for the operation of the IIT Network Centers.

 

Professional career

After graduating in Biological Sciences at the University of Pisa in 1995, she joined the Biophysics Institute of the National Research Council (CNR), where she worked on environmental issues and in particular on mercury pollution. From 1997 to 1998 she attended a master in Environmental Management and Control (EMAS) at the Sant’Anna High School in Pisa (SSSA), with an internship at the Office for Foreign Risks of Civil Responsibility and Accidents, of Assicurazioni Generali SpA of Trieste. The following year she was a research assistant at the Research Center in Microengineering (CRIM Lab) of the Sant'Anna High School in Pisa, a position she held until 2004. From the same year until 2009 she was a Biomedical Engineering Researcher at the same Sant’Anna High School. In November 2009 she became Team Leader at the Micro Bio-Robotics Center in Pontedera of the Italian Institute of Technology (IIT) in Genoa, and in February 2011 she was appointed Coordinator. In 2011 she obtained a research doctorate in Microsystems Engineering at the Tor Vergata University of Rome.

 

Scientific results

Barbara Mazzolai’s research field is soft and bioinspired robotics, an evolution of robotics that involves the use of non-rigid materials inspired by the living world, in particular invertebrate animals and plants. During her time at the CRIM Lab of the Sant'Anna High School, she founded a new research area specifically dedicated to microtechnologies and robotics applicable to the environment and agri-food, playing the role of project manager of European projects such as Octopus, aimed at developing a soft robot inspired by Octopus vulgaris, and DustBot, a network of autonomous robots that can be used to collect door-to-door waste and improve urban hygiene. Arriving at the head of IIT's Micro Bio-Robotics Center, she founded a new research line in the field of bio-inspired robotics and soft robotics called "Plantoid", which aims at the realization for the first time in the world of robots inspired by movements, to the sensorial and communication skills of plants and their roots for soil exploration and environmental monitoring.

 

 

Editorial work and publications

Barbara Mazzolai is a member of the editorial group of various scientific journals, including Bioinspiration & Biomimetics, Soft Robotics, Biomimetics, Robotics & Automation Letters, Frontiers in Bionics and Biomimetics, Micro-BioRobotics.

She is the author of numerous publications in international scientific journals, such as:

(2016) Laschi C, Mazzolai B, Cianchetti M. Soft robotics: Technologies and systems pushing the boundaries of robot abilities. Science Robotics, 1:(1). 

(2016) Larson C, Peele B, Li S, Robinson S, Totaro M, Beccai L, Mazzolai B, Shepherd R. Highly stretchable electroluminescent skin for optical signaling and tactile sensing. Science, 351(6277): 1071-1074. 

(2016) Argiolas A, Puleo GL, Sinibaldi E, Mazzolai B. Osmolyte cooperation affects turgor dynamics in plants. Scientific Reports, 6. 

(2016) Mazzolai B, Mattoli V. Robotics: Generation soft. Nature, 536 (7617), 400-401.

(2014) Sadeghi A, Tonazzini A, Popova L, Mazzolai B. A Novel Growing Device Inspired by Plant Root Soil Penetration Behaviors. PLoS ONE, 9:(2). 

(2014) Sinibaldi E, Argiolas A, Puleo GL, Mazzolai B. Another lesson from plants: the forward osmosis-based actuator. PLoS ONE, 9(7): e102461. 

(2014) Tramacere F, Kovalev A, Kleinteich T, Gorb SN, Mazzolai B. Structure and mechanical properties of Octopus vulgaris suckers. Journal of the Royal Society Interface, 11: 91, 20130816. 

(2013) Tramacere F, Beccai L, Kuba M, Gozzi A, Bifone A, Mazzolai B. The Morphology and Adhesion Mechanism of Octopus vulgaris suckers. PLoS ONE, 8(6): e65074. 

(2012) Mazzolai B, Margheri L, Cianchetti M, Dario P, Laschi C. Soft robotic arm inspired by the octopus. II. From artificial requirements to innovative technological solutions. Bioinspiration & Biomimetics, 7 025005. 

(2011) Mazzolai B, Mondini A, Corradi P, Laschi C, Mattoli V, Sinibaldi E, Dario P. A Miniaturized Mechatronic System Inspired by Plant Roots. IEEE Transaction on Mechatronics, 16(2), 201-212

Awards and prizes

In 2010 Barbara Mazzolai received the "Marisa Bellisario" award for the scientific and management activity of the "DustBot" project, in 2013 she was awarded the Pio Manzù Prize with the Medal of the Senate of the Italian Republic for her commitment as a scientist for the creation of technologies that open new paths to sustainable development. In 2015 she received, for the same reasons, the Genoa international award: a woman out of the chorus.

 

 

 

 

 

Hila Meller
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STEM area: Computer science

Competences: cybersecurity

Keywords: cloud, cybersecurity, identity management, support women in tech

Region: Lombardy


Position/Role

Vice President, Security Europe, BT (British Telecom)

Professional career

Hila has a bachelor degree in Computer Science and Mathematics from Bar Ilan University and an MBA in High Tech and innovation from the Technion institute.

2003 - 2008 She worked at Avnet Information Security in many different roles, the last one as Vice President Products and Services. 

In 2008 she worked at the start-up Eurekify as Vice President EMEA (Europe Middle East and Africa).

2009 - 2015 She worked at CA Technologies initially covering the role of Solutions Sales  Director EMEA and later that of Head of Security Strategy EMEA.

2016 - 2018 She worked at HP Enterprise Security Services as Head of South Europe.

In March 2018 she joined BT to lead a pan-European team of Security experts that are tasked with protecting some of the most important and complex organizations globally against the changing and evolving cyber threats.

 

Scientific results

Hila Meller has developed a significant experience along the years applying methods of Cyber Security both in military and defence environments as well as in the commercial and civilian space.

She is recognized as one of the first pioneering experts of Security for ERP systems, acting as a special Security advisor for more than 30 projects.

She developed a significant experience in the area of Identity and Access Management, contributing to the creation of a start-up which was later acquired by CA Technologies.

 

In BT she gained additional experience related to Cyber Intelligence use cases and the application of Artificial Intelligence in Cyber Security scenarios.

 

She is often invited to attend as keynote speaker at Information Technology conferences and trade exhibitions. Some past examples include: RSA Conference in San Francicso, Kuppinger Cole EIC conference in Munich, Cyberweek in Tel Aviv, Security summit in Milan  and Forum PA in Romea.

 

Editorial work and publications

Webinar - global security roundtable: perspectives, threats and risks per region

https://www.globalservices.bt.com/en/aboutus/events/security-roundtable-perspectives-threats-and-risks-per-region 

Masterclass: how to address risk and master security in 2019

https://www.globalservices.bt.com/en/aboutus/events/masterclass-how-to-address-risk-and-master-security2

 

Blog/ Article - Don’t let security cloud your views on digital transformation

https://www.globalservices.bt.com/en/insights/blogs/do-not-let-security-cloud-your-views-on-digital-transformation

Foreign Spies and Facebook: The Undeniable Truth

https://www.rsaconference.com/videos/foreign-spies-and-facebook-the-undeniable-truth

The Day After Tomorrow: Security Challenges of the Future

https://www.kuppingercole.com/watch/eic13_keynote_meller

Awards and prizes

2005 – Security Project of the year. The people magazine www.pc.co.il

Deny Menghini
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STEM area: Psychology and neurosciences

Competences: developmental neuropsychology

Keywords: developmental disorders, dyslexia, dyslexia therapy, genetic syndromes, language, learning

Region: Lazio


Position/Role

From 2010, she has a permanent contract as Psychologist and Psychotherapist at the Child Neuropsychiatric Unit of the Scientific Institute for Research and Healthcare Bambino Gesù Children’s Hospital.

Professional career

After her Master Degree in Developmental Psychology and Education at “La Sapienza” in Rome, she attended a Diploma Course in Psychopathology of Learning at the University of San Marino. Since 1998, she has been carrying out clinical and research activities at the Scientific Institute for Research and Healthcare Bambino Gesù Children’s Hospital. In 2004, she got a Ph.D in Cognitive Science and Rehabilitation. In 2016 she took a postgraduate diploma in Cognitive Behavior Therapy and in 2018, she got a national qualification as Full Professor in General Psychology, Psychobiology, and Psychometry.

Scientific results

Her field of interests concerns the link between behavior and brain in several neurodevelopmental disorders, such as specific learning disorders, language disorders, attention deficit hyperactivity disorder and intellectual disabilities. She is now coordinating a research team on the study of innovative rehabilitative perspectives as the use of non-invasive brain stimulation for neurodevelopmental disorders.  She has produced over than sixty peer-reviewed publications, several books and chapters for the neuropsychological assessment of children with neurodevelopmental disorders

Editorial work and publications

Costanzo F, Rossi S, Varuzza C, Varvara P, Vicari S, Menghini D. Long-lasting improvement following tDCS treatment combined with a training for reading in children and adolescents with dyslexia. Neuropsychologia. 2018. doi: 10.1016/j.neuropsychologia.2018.03.016.

Menghini D, Armando M, Calcagni M, Napolitano C, Pasqualetti P, Sergeant JA, Pani P, Vicari S. The influence of Generalized Anxiety Disorder on Executive Functions in children with ADHD. Eur Arch Psychiatry Clin Neurosci. 2018;268(4):349-357.

Costanzo F, Menghini D, Casula L, Amendola A, Mazzone L, Valeri G, Vicari S.Transcranial Direct Current Stimulation Treatment in an Adolescent with Autism and Drug-Resistant Catatonia. Brain Stimul. 2015; 8(6):1233-5.

Menghini D, Finzi A, Benassi M, Bolzani R, Facoetti A, Giovagnoli S, Ruffino M, Vicari S. Different underlying neurocognitive deficits in developmental dyslexia: a comparative study. Neuropsychologia. 2010;48(4):863-72.

Menghini D, Hagberg GE, Caltagirone C, Petrosini L, Vicari S. Implicit learning deficits in dyslexic adults: an fMRI study. Neuroimage. 2006;33(4):1218-26.

 

Awards and prizes

In 1998, she obtained the Fellowship Award granted by Pio Sodalizio dei Piceni (Rome).In 2010, she won a Grant by the Foundation Jerome Lejeune for studying the cerebral correlates of Down Syndrome. In 2012, she was funded by the Ministry of Health (Young Italian Researchers Grant) for studying innovative therapeutic approaches in neurodevelopmental disorders.

Giuseppina Micela
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STEM area: Physics

Competences: astronomy

Keywords: ESA (European Space Agency), extrasolar planets, harps-n, ISA (Italian Space Agency), space missions, star crowns, star formation, star-planet interaction, young stars

Region: Sicily


Position/Role

Director of research at Istituto Nazionale di Astrofisica, Osservatorio Astronomico di Palermo

Professional career

Physics degree at the Palermo University (1983)

CNR fellowship (1985), to spend a period at Harvard Smithsonian Center for Astrophysics - Cambridge (MA).

Scholarship from the Institute for Interdisciplinary Applications of Physics of the CNR (1986-87).

PhD in Physics at the University of Palermo (1991) with a thesis on the background emission in the band 0.16-3.5 keV.

From 1991, astronomer at the Astronomical Observatory of Palermo. She spent a period at the Department of Astronomy and Astrophysics of the University of Chicago thanks to a CNR / NATO Senior scholarship.

Today she is a Director of research and from 2012 to 2017 she was director of the Palermo Astronomical Observatory, a research facility of the National Institute of Astrophysics.

Giusi Micela has been member of several scientific teams for the study of the ESA space missions (Eddington, Plato, EChO, ARIEL) and of national and international projects from ground and from space. She has been the national responsible of the project funded by MIUR “A Way to Other Worlds – WOW”.  Moreover, she won a few EU programs, that allowed several European scientists to work at the Palermo Observatory. She is a member of the board of the Fundacion Galileo Galilei, of the board of the Gal Hassin, and of the International Advisory Committee of the Institute of Space Sciences (IEEC-CSIC), in Barcelona. Finally, she is member of the board of the PhD  Physics course at the Palermo University.

 

Scientific results

Her scientific activity is focused on the study of the physics of the upper stellar atmosphere and related themes. In particular, she was among the first researchers to carry out researches on the coronae of young stars through observations of open clusters and star formation regions with space missions (Einstein, Rosat, Chandra, XMM/Newton), determining how the high energy radiation in these stars is much more intense than today in the Sun. She has then dealt with the young stars, including star-forming regions and physical processes that govern the formation of stars in various bands of energy, and young stars in the solar neighborhood, highlighting how the region around the Sun was the site of a star formation episode over the last billion years.

Today, she works on extra-solar planets, in particular on the search of rocky planets around stars smaller than the Sun and on the study of star-planet interactions. She is co-investigator of the HARPS-N spectrograph at the Telescopio Nazionale Galileo, today the best instrument for the search of exoplanets in the northern hemisphere.  Finally, she is co-principal Investigator and Italian responsable for the ARIEL mission, an ESA mission for the observations of exo-planetary atmospheres.

Editorial work and publications

Giuseppina Micela is author of more than 300 papers published on international journals. In addition, she carries out activities of dissemination of astronomy, and in particular has published the book "Birth and death of the stars" for the series "Farsi un’idea" of “Il Mulino”. Selected papers are:

1.       [2016]Affer L, Micela G, Damasso M, Perger M, Ribas I et al.,  HADES RV program with HARPS-N at the TNG. GJ 3998: An early M-dwarf hosting a system of super-Earths, Astronomy & Astrophysics,  593, 117..

2.       [2013] Pepe F, Cameron Collier A, Latham, DW, Molinari E, Udry S, Bonomo A, Buchhave LA, Charbonneau,D, Cosentino R, Dressing CD, Dumusque X, Figueira P, Fiorenzano AFM, Gettel S, Harutyunyan A, Haywood RD, Horne K, Lopez-Morales M, Lovis C, Malavolta L, Mayor M, Micela Get al,An Earth-sized planet with an Earth-like density,  Nature, 503, 7476, 377-380.

3.        [2008]Penz T, Micela G,Lammer H, Influence of the evolving stellar X-ray luminosity distribution on exoplanetary mass lossAstronomy and Astrophysics, 477, 309-314.

4.        [2003] Favata F, Micela, G, Stellar Coronal Astronomy, Space Science Reviews, 108, 577-708.

5.       [1993]Micela G,Sciortino S, Favata F, Stellar birthrate in the Galaxy – Constraints from X-ray flux-limited surveys,Astrophysical Journal, 412, 618-624.